ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-13.PDB
Scoring matrix: NBP2_1YN8-13_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 20.87
Foldx random average score for Saccharomyces cerevisiae: 16.314

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 863043
Proteins after disorder filtering: 2927
 Total fragments: 36202
Proteins after pattern filtering: 1415
 Total fragments: 7121
Proteins after MINT filtering: 6
 Total fragments: 83


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

20.87

1.13

0.00

Best peptides

RRRRHPFY

0.00

-6.47

-7.60

         
Interactors      
Q01389

RYPQTPSY

9.98

-2.22

-3.35

YPQTPSYY

10.09

-3.82

-4.95

RPVPPDSS

11.27

-4.92

-6.05

P53933

RPPPPPIP

8.56

-7.72

-8.85

RVAPPPLP

9.37

-5.35

-6.48

RRRPPPPP

9.59

-5.10

-6.23

P48562

NPYRPHHN

10.66

-6.86

-7.99

RGPMHPNN

11.68

-4.03

-5.16

APKRPDAD

11.78

-5.17

-6.30

Q03497

IPSRPAPK

10.53

-7.15

-8.28

RPAPKPPS

11.03

-5.09

-6.22

GKFIPSRP

11.90

-4.50

-5.63

P08018

RAPRRPLS

6.08

-8.56

-9.69

HPTRPNVA

10.65

-6.30

-7.43

RPNVAPHK

10.97

-5.51

-6.64

Q12469

LKPFPRPS

12.98

-4.04

-5.17

PFPRPSDD

13.68

-3.67

-4.80

RLAPSAPA

13.82

-3.82

-4.95

 


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