ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-11.PDB
Scoring matrix: NBP2_1YN8-11_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.97
Foldx random average score for Saccharomyces cerevisiae: 9.882

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2186688
Proteins after random average filtering: 5078
 Total fragments: 938369
Proteins after disorder filtering: 3192
 Total fragments: 55144
Proteins after pattern filtering: 1543
 Total fragments: 9269
Proteins after MINT filtering: 6
 Total fragments: 100


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.97

-0.72

0.00

Best peptides

YPPLHPY

0.00

-7.43

-6.71

         
Interactors      
Q01389

YPQTPSY

4.28

-7.23

-6.51

FPNLTPN

6.23

-5.36

-4.64

SKPLPPQ

6.40

-5.21

-4.49

P53933

RRPPPPP

5.13

-5.78

-5.06

RPPPPPI

5.26

-6.32

-5.60

RRRPPPP

5.30

-6.78

-6.06

P48562

NPYRPHH

5.36

-5.21

-4.49

RGPMHPN

6.09

-6.92

-6.20

FPRGPMH

6.65

-4.45

-3.73

Q03497

FPSKNPL

5.16

-5.54

-4.82

RPAPKPP

5.62

-5.37

-4.65

LPPIPPT

6.07

-6.38

-5.66

P08018

RAPRRPL

5.99

-7.46

-6.74

RPNVAPH

6.34

-6.34

-5.62

PPPRLPS

6.96

-7.31

-6.59

Q12469

LKPFPRP

6.26

-5.62

-4.90

KPFPRPS

8.00

-4.59

-3.87

RLAPSAP

8.64

-3.88

-3.16

 


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