ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-10.PDB
Scoring matrix: NBP2_1YN8-10_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.33
Foldx random average score for Saccharomyces cerevisiae: 18.045

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 1338769
Proteins after disorder filtering: 3342
 Total fragments: 106333
Proteins after pattern filtering: 1641
 Total fragments: 13710
Proteins after MINT filtering: 7
 Total fragments: 164


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.33

5.53

0.00

Best peptides

RPIRGWWW

0.00

-4.75

-10.28

         
Interactors      
Q01389

RPVPPDSS

9.18

0.21

-5.32

KPLPPQLL

9.94

1.49

-4.04

YPQTPSYY

10.73

0.04

-5.49

P53933

RPPPPPIP

7.48

-0.60

-6.13

RVAPPPLP

8.71

-0.20

-5.73

RRRPPPPP

10.53

-1.49

-7.02

P48562

QFPRGPMH

6.05

-5.44

-10.97

NPYRPHHN

9.03

1.47

-4.06

FPRGPMHP

9.22

1.37

-4.16

Q03497

PKVKPSKP

9.98

1.79

-3.74

GKFIPSRP

9.99

0.50

-5.03

KPSKPEAK

10.22

0.71

-4.82

Q12469

PFPRPSDD

11.04

1.43

-4.10

KPFPRPSD

11.88

1.13

-4.40

HRLAPSAP

13.05

3.20

-2.33

P25293

PHNTPASV

13.31

3.17

-2.36

P08018

RPNVAPHK

7.11

-3.96

-9.49

RAPRRPLS

9.67

-1.96

-7.49

APRRPLST

10.48

-0.02

-5.55

 


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