ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-8.PDB
Scoring matrix: NBP2_1SEM-8_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.89
Foldx random average score for Saccharomyces cerevisiae: 10.855

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 876583
Proteins after disorder filtering: 2964
 Total fragments: 46473
Proteins after pattern filtering: 1537
 Total fragments: 9951
Proteins after MINT filtering: 7
 Total fragments: 124


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

13.89

-2.31

0.00

Best peptides

HRRPRPRR

0.00

-8.08

-5.77

         
Interactors      
Q01389

RSKPLPPQ

6.90

-7.20

-4.89

STPSRPVP

6.95

-8.25

-5.94

SPPPIPKT

7.26

-7.73

-5.42

P53933

APPPLPNR

4.29

-8.79

-6.48

RRRPPPPP

4.49

-6.24

-3.93

TRRRPPPP

5.02

-6.21

-3.90

P48562

LNPYRPHH

4.86

-7.46

-5.15

QAPKRPDA

7.21

-6.51

-4.20

PRAPYPSN

7.27

-6.86

-4.55

Q03497

FIPSRPAP

4.86

-7.78

-5.47

KPKVKPSK

6.16

-7.75

-5.44

VKPSKPEA

6.45

-6.82

-4.51

Q12469

KPFPRPSD

6.72

-6.50

-4.19

ELKPFPRP

6.94

-5.95

-3.64

LKPFPRPS

8.57

-4.15

-1.84

P25293

TPHNTPAS

10.28

-4.25

-1.94

P08018

PRRPLSTQ

5.50

-4.79

-2.48

QHPTRPNV

6.74

-7.48

-5.17

RAPRRPLS

6.78

-7.21

-4.90

 


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