ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-4.PDB
Scoring matrix: NBP2_1SEM-4_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.62
Foldx random average score for Saccharomyces cerevisiae: 19.588

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 1023265
Proteins after disorder filtering: 3055
 Total fragments: 67215
Proteins after pattern filtering: 1602
 Total fragments: 15725
Proteins after MINT filtering: 7
 Total fragments: 192


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.62

2.11

0.00

Best peptides

MIPRRFRHMR

0.00

-6.55

-8.66

         
Interactors      
Q01389

APKREAPKPP

10.40

-5.90

-8.01

EPSTPSRPVP

11.77

-4.74

-6.85

SPSYPSIFRR

12.20

-3.74

-5.85

P53933

VRTRRRPPPP

8.30

-8.86

-10.97

RTRRRPPPPP

10.16

-9.61

-11.72

PPPLPNRQLP

10.58

-6.05

-8.16

P48562

SPLNPYRPHH

9.59

-6.56

-8.67

QPQRTAPKPP

10.16

-5.57

-7.68

QTMRQAPKRP

11.00

-6.68

-8.79

Q03497

IPSRPAPKPP

8.60

-6.28

-8.39

LPPIPPTKSK

11.53

-2.36

-4.47

KFIPSRPAPK

12.35

-3.50

-5.61

Q12469

RPHRLAPSAP

12.06

-5.30

-7.41

RLAPSAPATK

14.47

-1.73

-3.84

ELKPFPRPSD

14.80

-2.29

-4.40

P25293

APTPHNTPAS

15.99

-2.67

-4.78

TPHNTPASVL

17.06

-0.80

-2.91

DNAPTPHNTP

18.00

0.02

-2.09

P08018

HPTRPNVAPH

9.77

-5.32

-7.43

IVDGPPPRLP

11.88

-4.65

-6.76

PPPRLPSDKF

12.08

-2.14

-4.25

 


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