ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-27.PDB
Scoring matrix: NBP2_1SEM-27_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 15.78
Foldx random average score for Saccharomyces cerevisiae: 13.779

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 941379
Proteins after disorder filtering: 3078
 Total fragments: 59100
Proteins after pattern filtering: 1594
 Total fragments: 13535
Proteins after MINT filtering: 7
 Total fragments: 174


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

15.78

-2.07

0.00

Best peptides

MRRPRRIRR

0.00

-7.59

-5.52

         
Interactors      
Q01389

SSSPPPIPK

7.29

-5.16

-3.09

KRSKPLPPQ

8.14

-5.31

-3.24

KREAPKPPA

8.55

-5.62

-3.55

P53933

RRRPPPPPI

5.59

-6.25

-4.18

RPPPPPIPS

5.76

-6.92

-4.85

RRPPPPPIP

6.15

-6.19

-4.12

P48562

MRQAPKRPD

6.93

-6.62

-4.55

RTAPKPPIS

8.18

-4.82

-2.75

ISAPRAPYP

8.61

-6.40

-4.33

Q03497

QHKPKVKPS

7.18

-5.87

-3.80

SRPAPKPPS

9.01

-5.51

-3.44

PSRPAPKPP

9.15

-5.88

-3.81

Q12469

ELKPFPRPS

7.60

-5.81

-3.74

KPFPRPSDD

9.45

-3.74

-1.67

LKPFPRPSD

10.17

-3.37

-1.30

P25293

APTPHNTPA

9.95

-5.72

-3.65

P08018

LSTQHPTRP

8.51

-7.12

-5.05

VDGPPPRLP

8.65

-5.10

-3.03

DGPPPRLPS

8.96

-5.49

-3.42

 


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