ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-25.PDB
Scoring matrix: NBP2_1SEM-25_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.42
Foldx random average score for Saccharomyces cerevisiae: 14.994

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 874292
Proteins after disorder filtering: 2804
 Total fragments: 39880
Proteins after pattern filtering: 1473
 Total fragments: 9833
Proteins after MINT filtering: 6
 Total fragments: 125


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.42

-1.16

0.00

Best peptides

HRRRRPPFM

0.00

-8.98

-7.82

         
Interactors      
Q01389

RYPQTPSYY

8.83

-6.91

-5.75

PKREAPKPP

9.72

-6.77

-5.61

STPSRPVPP

9.84

-4.92

-3.76

P53933

RRRPPPPPI

6.10

-8.13

-6.97

RTRRRPPPP

6.29

-8.31

-7.15

TRRRPPPPP

7.05

-8.52

-7.36

P48562

PYRPHHNMI

7.56

-3.14

-1.98

LNPYRPHHN

7.79

-6.84

-5.68

TMRQAPKRP

8.15

-5.51

-4.35

Q03497

FIPSRPAPK

8.11

-6.17

-5.01

VKPSKPEAK

8.99

-7.57

-6.41

SFPSKNPLK

9.61

-5.86

-4.70

P08018

PRRPLSTQH

7.66

-7.23

-6.07

TRPNVAPHK

9.38

-8.08

-6.92

RAPRRPLST

10.93

-5.33

-4.17

Q12469

PHRLAPSAP

11.80

-4.45

-3.29

LKPFPRPSD

12.50

-2.99

-1.83

ELKPFPRPS

12.84

-3.67

-2.51

 


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