ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-23.PDB
Scoring matrix: NBP2_1SEM-23_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 18.72
Foldx random average score for Saccharomyces cerevisiae: 14.666

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2186688
Proteins after random average filtering: 5078
 Total fragments: 955663
Proteins after disorder filtering: 3096
 Total fragments: 39729
Proteins after pattern filtering: 1188
 Total fragments: 3947
Proteins after MINT filtering: 7
 Total fragments: 48


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

18.72

-2.02

0.00

Best peptides

RRRRRRR

0.00

-4.56

-2.54

         
Interactors      
Q01389

APTKPNP

11.80

-5.01

-2.99

TPSRPVP

12.03

-5.53

-3.51

EAPKPPA

12.58

-2.00

0.02

P53933

PPPLPNR

10.07

-5.79

-3.77

LPMELPH

13.19

-4.72

-2.70

DLPMELP

13.75

-3.94

-1.92

P48562

SPLNPYR

10.36

-5.03

-3.01

QFPRGPM

10.74

-4.67

-2.65

NPYRPHH

10.79

-4.72

-2.70

Q03497

PKVKPSK

9.96

-6.29

-4.27

FPSKNPL

10.93

-4.10

-2.08

HKPKVKP

11.50

-4.06

-2.04

Q12469

LKPFPRP

10.75

-5.62

-3.60

PFPRPSD

12.81

-3.84

-1.82

P25293

PTPHNTP

14.48

-3.34

-1.32

P08018

RAPRRPL

8.27

-6.77

-4.75

APRRPLS

8.48

-4.88

-2.86

PPRLPSD

10.29

-5.33

-3.31

 


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