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Matrix information:
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ADAN-name: NBP2_1SEM-21.PDB
Scoring matrix: NBP2_1SEM-21_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 19.22
Foldx random average score for Saccharomyces cerevisiae: 18.014 Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
Proteins belonging to other specie: 0
Nš of interactions described: 20
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
Total fragments: 2171454
Proteins after random average filtering: 5078
Total fragments: 1227001
Proteins after disorder filtering: 3034
Total fragments: 48716
Proteins after pattern filtering: 1196
Total fragments: 3124
Proteins after MINT filtering: 6
Total fragments: 36
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAGGAAAA |
19.22
|
-0.09 |
0.00 |
| Best peptides |
EWRFRRPTMK |
0.00
|
-2.11 |
-2.02 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q01389 |
REAPKPPANT |
14.98
|
-3.46 |
-3.37 |
|
RSKPLPPQLL |
15.62
|
-2.66 |
-2.57 |
|
RRYPQTPSYY |
15.83
|
-2.45 |
-2.36 |
| P53933 |
PPPPIPSTQK |
12.73
|
-2.99 |
-2.90 |
|
VSYPGNPTSR |
13.60
|
-2.39 |
-2.30 |
|
APPPLPNRQL |
16.95
|
-3.41 |
-3.32 |
| P48562 |
PLNPYRPHHN |
13.92
|
-4.54 |
-4.45 |
|
LNPYRPHHNM |
14.67
|
-3.92 |
-3.83 |
|
PRGPMHPNNS |
15.55
|
-1.83 |
-1.74 |
| Q03497 |
PLPPIPPTKS |
13.95
|
-3.09 |
-3.00 |
|
TGLPGSPQVS |
14.58
|
-1.38 |
-1.29 |
|
KVKPSKPEAK |
14.77
|
-0.51 |
-0.42 |
| P08018 |
GPPPRLPSDK |
14.56
|
-1.81 |
-1.72 |
|
TQHPTRPNVA |
16.16
|
-2.24 |
-2.15 |
|
RAPRRPLSTQ |
17.02
|
-2.29 |
-2.20 |
| Q12469 |
RLAPSAPATK |
11.77
|
-2.52 |
-2.43 |
|
LAPSAPATKN |
17.92
|
-2.13 |
-2.04 |
|
