ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-20.PDB
Scoring matrix: NBP2_1SEM-20_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.54
Foldx random average score for Saccharomyces cerevisiae: 15.694

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 953297
Proteins after disorder filtering: 3035
 Total fragments: 44420
Proteins after pattern filtering: 1375
 Total fragments: 5252
Proteins after MINT filtering: 7
 Total fragments: 70


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.54

-2.96

0.00

Best peptides

RRRRPGHRM

0.00

-8.00

-5.04

         
Interactors      
Q01389

YPQTPSYYY

8.90

-5.61

-2.65

KRSKPLPPQ

9.56

-8.45

-5.49

RPVPPDSSY

10.02

-9.09

-6.13

P53933

PPPLPNRQL

11.22

-5.77

-2.81

YNDLPMELP

12.20

-5.97

-3.01

PPPIPSTQK

14.65

-3.84

-0.88

P48562

NPYRPHHNM

7.31

-8.21

-5.25

MRQAPKRPD

11.47

-4.17

-1.21

FPRGPMHPN

12.14

-5.70

-2.74

Q03497

KKSFPSKNP

10.46

-4.84

-1.88

KPSKPEAKS

10.57

-4.99

-2.03

HKPKVKPSK

10.67

-5.45

-2.49

Q12469

LKPFPRPSD

11.25

-6.31

-3.35

RLAPSAPAT

14.03

-7.51

-4.55

HRLAPSAPA

14.43

-2.26

0.70

P25293

PHNTPASVL

15.14

-1.64

1.32

NAPTPHNTP

15.16

-3.97

-1.01

P08018

PPRLPSDKF

11.20

-5.92

-2.96

APRRPLSTQ

12.49

-6.11

-3.15

HPTRPNVAP

13.39

-8.23

-5.27

 


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