ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-18.PDB
Scoring matrix: NBP2_1SEM-18_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 21.4
Foldx random average score for Saccharomyces cerevisiae: 19.301

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 910564
Proteins after disorder filtering: 3124
 Total fragments: 65390
Proteins after pattern filtering: 1499
 Total fragments: 8531
Proteins after MINT filtering: 7
 Total fragments: 96


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

21.40

2.56

0.00

Best peptides

RPPIPSIFFR

0.00

-1.91

-4.47

         
Interactors      
Q01389

RYPQTPSYYY

10.50

-3.89

-6.45

SPSYPSIFRR

11.05

-1.96

-4.52

ASPSYPSIFR

11.85

-1.17

-3.73

P53933

RPPPPPIPST

13.60

-0.78

-3.34

PPPIPSTQKP

13.69

-0.53

-3.09

RRPPPPPIPS

15.62

-5.43

-7.99

P48562

NPYRPHHNMI

11.80

-1.64

-4.20

LNPYRPHHNM

13.24

-1.57

-4.13

PSPSPLNPYR

13.58

-0.72

-3.28

Q03497

LPPIPPTKSK

10.15

-3.82

-6.38

FPSKNPLKNS

13.55

-5.55

-8.11

KPSKPEAKSK

14.04

-4.00

-6.56

Q12469

RPHRLAPSAP

16.23

-2.70

-5.26

APSAPATKNH

16.36

-1.55

-4.11

LAPSAPATKN

16.96

-0.67

-3.23

P25293

TPHNTPASVL

18.08

1.51

-1.05

NAPTPHNTPA

18.58

-0.63

-3.19

P08018

PPRLPSDKFS

10.79

-5.05

-7.61

PPPRLPSDKF

15.31

1.25

-1.31

APRRPLSTQH

16.62

-2.26

-4.82

 


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