ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-16.PDB
Scoring matrix: NBP2_1SEM-16_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.78
Foldx random average score for Saccharomyces cerevisiae: 17.956

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 916438
Proteins after disorder filtering: 3184
 Total fragments: 60812
Proteins after pattern filtering: 1542
 Total fragments: 8668
Proteins after MINT filtering: 7
 Total fragments: 106


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.78

0.78

0.00

Best peptides

RFPRPSRRY

0.00

-2.82

-3.60

         
Interactors      
Q01389

YPQTPSYYY

8.35

-3.42

-4.20

RYPQTPSYY

10.18

-3.60

-4.38

RPVPPDSSY

12.20

-2.80

-3.58

P53933

PPPIPSTQK

11.52

-1.39

-2.17

YNDLPMELP

13.45

-3.46

-4.24

KRVAPPPLP

14.10

-3.54

-4.32

P48562

NPYRPHHNM

9.92

-4.72

-5.50

KPPISAPRA

10.16

-2.20

-2.98

QFPRGPMHP

11.05

-3.62

-4.40

Q03497

KPKVKPSKP

11.26

-5.34

-6.12

KQHKPKVKP

11.55

-4.35

-5.13

IPSRPAPKP

11.66

-5.15

-5.93

Q12469

PHRLAPSAP

14.66

-3.26

-4.04

LAPSAPATK

14.75

-0.12

-0.90

PSAPATKNH

16.26

-2.33

-3.11

P25293

NAPTPHNTP

16.41

-1.36

-2.14

P08018

PPRLPSDKF

8.91

-4.67

-5.45

RAPRRPLST

12.32

-2.84

-3.62

PPPRLPSDK

13.09

-2.31

-3.09

 


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