ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-14.PDB
Scoring matrix: NBP2_1SEM-14_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.9
Foldx random average score for Saccharomyces cerevisiae: 16.331

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 992521
Proteins after disorder filtering: 2881
 Total fragments: 33083
Proteins after pattern filtering: 1281
 Total fragments: 4531
Proteins after MINT filtering: 7
 Total fragments: 56


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.90

-2.77

0.00

Best peptides

RWHRRFKHM

0.00

-10.45

-7.68

         
Interactors      
Q01389

KRSKPLPPQ

13.72

-7.67

-4.90

FPNLTPNST

13.92

-7.99

-5.22

RYPQTPSYY

14.07

-5.61

-2.84

P53933

PPPLPNRQL

11.96

-8.29

-5.52

PPPIPSTQK

12.22

-6.52

-3.75

RRRPPPPPI

14.51

-8.05

-5.28

P48562

NPYRPHHNM

9.25

-11.04

-8.27

APKRPDADV

12.74

-7.93

-5.16

KPPISAPRA

12.78

-7.25

-4.48

Q03497

HKPKVKPSK

12.30

-5.86

-3.09

LPPIPPTKS

12.83

-8.01

-5.24

KPSKPEAKS

13.22

-5.88

-3.11

Q12469

PFPRPSDDD

15.29

-5.16

-2.39

KPFPRPSDD

15.50

-3.76

-0.99

RLAPSAPAT

16.23

-5.70

-2.93

P25293

PHNTPASVL

14.93

-6.04

-3.27

TPHNTPASV

15.03

-4.34

-1.57

P08018

RAPRRPLST

10.37

-7.43

-4.66

PPPRLPSDK

11.42

-8.72

-5.95

APRRPLSTQ

13.17

-7.39

-4.62

 


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