ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-12.PDB
Scoring matrix: NBP2_1SEM-12_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.34
Foldx random average score for Saccharomyces cerevisiae: 8.164

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 871711
Proteins after disorder filtering: 3091
 Total fragments: 47348
Proteins after pattern filtering: 1536
 Total fragments: 10045
Proteins after MINT filtering: 6
 Total fragments: 132


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

10.34

-2.07

0.00

Best peptides

RYMMRMWK

0.00

-5.52

-3.45

         
Interactors      
Q01389

PSYPSIFR

4.67

-4.08

-2.01

SSPPPIPK

4.69

-3.31

-1.24

RSKPLPPQ

4.92

-4.16

-2.09

P53933

RRRPPPPP

4.07

-4.88

-2.81

VAPPPLPN

4.77

-4.52

-2.45

DLPMELPH

4.84

-4.03

-1.96

P48562

VAKPKKPA

4.93

-4.25

-2.18

PYRPHHNM

5.45

-4.80

-2.73

IGPAPRPP

5.59

-4.03

-1.96

Q03497

KVKPSKPE

4.53

-3.90

-1.83

KSFPSKNP

5.31

-3.44

-1.37

HKPKVKPS

5.60

-3.80

-1.73

P08018

DGPPPRLP

5.18

-4.49

-2.42

GPPPRLPS

5.22

-5.00

-2.93

TQHPTRPN

5.24

-7.48

-5.41

Q12469

ELKPFPRP

4.90

-3.61

-1.54

LKPFPRPS

5.19

-4.67

-2.60

KPFPRPSD

6.18

-3.87

-1.80

 


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