ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-10.PDB
Scoring matrix: NBP2_1SEM-10_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.75
Foldx random average score for Saccharomyces cerevisiae: 14.597

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 1020375
Proteins after disorder filtering: 3226
 Total fragments: 57336
Proteins after pattern filtering: 1514
 Total fragments: 7854
Proteins after MINT filtering: 7
 Total fragments: 100


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.75

-1.02

0.00

Best peptides

RPRRCRWP

0.00

-5.99

-4.97

         
Interactors      
Q01389

RPVPPDSS

10.27

-4.82

-3.80

FPNLTPNS

10.45

-3.75

-2.73

RSKPLPPQ

10.65

-4.00

-2.98

P53933

RPPPPPIP

8.25

-6.08

-5.06

RRRPPPPP

10.20

-6.01

-4.99

RVAPPPLP

11.05

-4.82

-3.80

P48562

QFPRGPMH

8.38

-4.42

-3.40

SAPRAPYP

9.14

-3.77

-2.75

NPYRPHHN

9.84

-3.72

-2.70

Q03497

FPSKNPLK

7.79

-2.87

-1.85

RPAPKPPS

9.84

-6.37

-5.35

KPKVKPSK

10.24

-2.93

-1.91

Q12469

KPFPRPSD

10.65

-2.66

-1.64

RLAPSAPA

12.40

-3.58

-2.56

PSAPATKN

12.40

-2.52

-1.50

P25293

TPHNTPAS

13.73

-1.74

-0.72

P08018

RPNVAPHK

5.00

-7.07

-6.05

RAPRRPLS

6.81

-7.15

-6.13

PPPRLPSD

9.71

-3.53

-2.51

 


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