ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-1.PDB
Scoring matrix: NBP2_1SEM-1_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 24.55
Foldx random average score for Saccharomyces cerevisiae: 21.263

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 1230335
Proteins after disorder filtering: 3069
 Total fragments: 68587
Proteins after pattern filtering: 1599
 Total fragments: 16016
Proteins after MINT filtering: 7
 Total fragments: 184


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

24.55

-2.83

0.00

Best peptides

WPRHRRRHRR

0.00

-8.19

-5.36

         
Interactors      
Q01389

SPSYPSIFRR

10.63

-5.97

-3.14

EPSTPSRPVP

13.15

-6.06

-3.23

APKREAPKPP

14.63

-8.95

-6.12

P53933

VRTRRRPPPP

13.41

-11.86

-9.03

PPPLPNRQLP

14.77

-10.01

-7.18

RVAPPPLPNR

15.54

-9.09

-6.26

P48562

PPISAPRAPY

12.40

-12.39

-9.56

SPLNPYRPHH

12.94

-9.24

-6.41

TNGQFPRGPM

14.04

-9.89

-7.06

Q03497

HKQHKPKVKP

12.67

-7.88

-5.05

IPSRPAPKPP

12.97

-9.06

-6.23

HKPKVKPSKP

13.70

-8.89

-6.06

Q12469

LKPFPRPSDD

16.01

-8.55

-5.72

ELKPFPRPSD

16.48

-9.82

-6.99

RPHRLAPSAP

16.67

-9.44

-6.61

P25293

TPHNTPASVL

19.95

-6.39

-3.56

APTPHNTPAS

20.93

-4.90

-2.07

NAPTPHNTPA

21.24

-5.20

-2.37

P08018

PLSTQHPTRP

13.56

-9.76

-6.93

PPPRLPSDKF

14.92

-7.53

-4.70

HPTRPNVAPH

16.70

-8.45

-5.62

 


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