ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-9.PDB
Scoring matrix: NBP2_1GCQ-9_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 20.46
Foldx random average score for Saccharomyces cerevisiae: 16.596

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 891915
Proteins after disorder filtering: 2975
 Total fragments: 37129
Proteins after pattern filtering: 1442
 Total fragments: 7816
Proteins after MINT filtering: 6
 Total fragments: 97


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

20.46

-2.58

0.00

Best peptides

RRWRPPKW

0.00

-12.42

-9.84

         
Interactors      
Q01389

TPSRPVPP

9.34

-7.80

-5.22

KRSKPLPP

11.14

-7.88

-5.30

YPQTPSYY

11.57

-6.77

-4.19

P53933

TRRRPPPP

7.80

-8.99

-6.41

RVAPPPLP

10.77

-9.28

-6.70

RPPPPPIP

10.89

-10.96

-8.38

P48562

QFPRGPMH

7.84

-9.50

-6.92

NPYRPHHN

9.40

-7.72

-5.14

APKRPDAD

9.72

-8.01

-5.43

Q03497

IPSRPAPK

8.11

-9.21

-6.63

PKVKPSKP

11.08

-7.89

-5.31

FPSKNPLK

12.04

-6.35

-3.77

P08018

RAPRRPLS

6.72

-10.71

-8.13

HPTRPNVA

9.07

-10.12

-7.54

APRRPLST

9.27

-8.18

-5.60

Q12469

PFPRPSDD

11.08

-7.11

-4.53

LKPFPRPS

13.18

-6.50

-3.92

ELKPFPRP

14.80

-6.10

-3.52

 


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