ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-8.PDB
Scoring matrix: NBP2_1GCQ-8_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.93
Foldx random average score for Saccharomyces cerevisiae: 12.709

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 882058
Proteins after disorder filtering: 3028
 Total fragments: 47271
Proteins after pattern filtering: 1547
 Total fragments: 10183
Proteins after MINT filtering: 7
 Total fragments: 123


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.93

-2.52

0.00

Best peptides

HWRPRPPR

0.00

-6.30

-3.78

         
Interactors      
Q01389

STPSRPVP

8.03

-7.75

-5.23

RSKPLPPQ

8.55

-7.50

-4.98

TEPSTPSR

8.57

-6.98

-4.46

P53933

APPPLPNR

4.47

-9.46

-6.94

RRRPPPPP

7.04

-7.39

-4.87

TRRRPPPP

7.47

-6.22

-3.70

P48562

LNPYRPHH

7.70

-7.01

-4.49

QAPKRPDA

8.49

-6.79

-4.27

PSPLNPYR

8.80

-5.52

-3.00

Q03497

FIPSRPAP

5.85

-7.72

-5.20

HAPTTPNR

7.89

-7.03

-4.51

KPKVKPSK

8.13

-8.21

-5.69

Q12469

KPFPRPSD

8.34

-10.05

-7.53

ELKPFPRP

10.49

-6.20

-3.68

LKPFPRPS

11.18

-3.97

-1.45

P25293

APTPHNTP

12.37

-3.56

-1.04

P08018

PRRPLSTQ

7.75

-6.39

-3.87

RAPRRPLS

8.16

-6.98

-4.46

QHPTRPNV

8.20

-7.97

-5.45

 


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