ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-5.PDB
Scoring matrix: NBP2_1GCQ-5_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.33
Foldx random average score for Saccharomyces cerevisiae: 19.095

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 935164
Proteins after disorder filtering: 3074
 Total fragments: 59621
Proteins after pattern filtering: 1603
 Total fragments: 14582
Proteins after MINT filtering: 7
 Total fragments: 178


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.33

4.04

0.00

Best peptides

MIWRPPRNHW

0.00

-9.67

-13.71

         
Interactors      
Q01389

PSSSPPPIPK

12.50

-5.00

-9.04

SRPVPPDSSY

12.54

-5.03

-9.07

KRSKPLPPQL

12.98

-9.99

-14.03

P53933

RTRRRPPPPP

10.67

-9.32

-13.36

KRVAPPPLPN

11.24

-4.97

-9.00

RVAPPPLPNR

11.34

-7.43

-11.47

P48562

YHHQGPSPSP

9.98

-5.97

-10.00

FQNIGPAPRP

10.67

-6.31

-10.34

TNGQFPRGPM

10.78

-6.14

-10.18

Q03497

FIPSRPAPKP

9.58

-6.86

-10.90

EQPLPPIPPT

13.08

-4.16

-8.20

FPSKNPLKNS

13.10

-4.43

-8.46

Q12469

LAPSAPATKN

15.30

-5.32

-9.36

ELKPFPRPSD

15.30

-4.30

-8.34

PHRLAPSAPA

15.36

-3.37

-7.41

P25293

DNAPTPHNTP

15.50

-3.95

-7.99

PHNTPASVLN

15.80

-3.32

-7.36

NAPTPHNTPA

18.41

-4.02

-8.05

P08018

RAPRRPLSTQ

11.30

-7.66

-11.70

IVDGPPPRLP

11.39

-6.63

-10.66

PPPRLPSDKF

13.36

-7.55

-11.59

 


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