ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-28.PDB
Scoring matrix: NBP2_1GCQ-28_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 24.92
Foldx random average score for Saccharomyces cerevisiae: 19.930

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 1050914
Proteins after disorder filtering: 2936
 Total fragments: 42227
Proteins after pattern filtering: 1427
 Total fragments: 7441
Proteins after MINT filtering: 7
 Total fragments: 91


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

24.92

-0.37

0.00

Best peptides

RRRFFTWPHR

0.00

-8.51

-8.14

         
Interactors      
Q01389

SPSYPSIFRR

12.61

-11.00

-10.63

PQTPSYYYDR

13.09

-5.83

-5.46

SRTEPSTPSR

14.20

-10.73

-10.36

P53933

RVAPPPLPNR

8.44

-12.82

-12.45

RPPPPPIPST

12.88

-12.37

-12.00

PPPPIPSTQK

14.23

-8.21

-7.84

P48562

KQPQSPLSSQ

14.56

-7.10

-6.73

NPYRPHHNMI

14.87

-11.32

-10.95

RTAPKPPISA

15.68

-7.48

-7.11

Q03497

LPPIPPTKSK

11.89

-9.21

-8.84

KPSKPEAKSK

12.34

-9.09

-8.72

QHKPKVKPSK

12.83

-8.26

-7.89

Q12469

RLAPSAPATK

11.66

-9.07

-8.70

LKPFPRPSDD

18.86

-6.87

-6.50

PFPRPSDDDY

19.61

-5.40

-5.03

P25293

PHNTPASVLN

18.22

-6.70

-6.33

PTPHNTPASV

19.30

-7.84

-7.47

P08018

RAPRRPLSTQ

13.06

-9.19

-8.82

PTRPNVAPHK

15.31

-5.85

-5.48

GPPPRLPSDK

15.46

-8.10

-7.73

 


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