ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-25.PDB
Scoring matrix: NBP2_1GCQ-25_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.54
Foldx random average score for Saccharomyces cerevisiae: 14.154

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5077
 Total fragments: 962257
Proteins after disorder filtering: 2942
 Total fragments: 39998
Proteins after pattern filtering: 1451
 Total fragments: 8426
Proteins after MINT filtering: 6
 Total fragments: 100


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.54

-0.93

0.00

Best peptides

HRKPIPPRN

0.00

-10.26

-9.33

         
Interactors      
Q01389

RSKPLPPQL

8.70

-6.18

-5.25

RYPQTPSYY

9.10

-7.94

-7.01

REAPKPPAN

9.38

-4.43

-3.50

P53933

APPPLPNRQ

6.31

-8.95

-8.02

RRRPPPPPI

7.95

-9.70

-8.77

RRPPPPPIP

10.17

-10.52

-9.59

P48562

LNPYRPHHN

6.59

-7.35

-6.42

PYRPHHNMI

9.41

-7.89

-6.96

PRGPMHPNN

9.43

-8.80

-7.87

Q03497

PLPPIPPTK

8.28

-7.25

-6.32

SFPSKNPLK

8.38

-6.86

-5.93

VKPSKPEAK

8.81

-8.01

-7.08

P08018

TRPNVAPHK

7.21

-10.18

-9.25

PRRPLSTQH

8.88

-9.40

-8.47

RAPRRPLST

11.20

-6.35

-5.42

Q12469

ELKPFPRPS

8.81

-5.61

-4.68

APSAPATKN

12.57

-1.71

-0.78

KPFPRPSDD

12.99

-4.39

-3.46

 


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