ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-21.PDB
Scoring matrix: NBP2_1GCQ-21_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 20.05
Foldx random average score for Saccharomyces cerevisiae: 18.412

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 1231693
Proteins after disorder filtering: 2999
 Total fragments: 48549
Proteins after pattern filtering: 1142
 Total fragments: 3015
Proteins after MINT filtering: 6
 Total fragments: 37


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

20.05

-1.17

0.00

Best peptides

EWRMGRPTRR

0.00

-4.39

-3.22

         
Interactors      
Q01389

RSKPLPPQLL

14.18

-3.93

-2.76

RRYPQTPSYY

15.44

-4.38

-3.21

QFPNLTPNST

15.74

-5.91

-4.74

P53933

VSYPGNPTSR

11.93

-4.77

-3.60

PPPPIPSTQK

13.90

-3.98

-2.81

APPPLPNRQL

15.28

-5.58

-4.41

P48562

PLNPYRPHHN

12.51

-3.50

-2.33

PYRPHHNMIN

13.93

-6.29

-5.12

PRAPYPSNQN

14.65

-2.57

-1.40

Q03497

THAPTTPNRT

13.02

-5.30

-4.13

PLPPIPPTKS

15.74

-4.92

-3.75

FPSKNPLKNS

16.64

-2.94

-1.77

P08018

TQHPTRPNVA

15.05

-2.84

-1.67

GPPPRLPSDK

17.07

-2.46

-1.29

RAPRRPLSTQ

17.39

-5.88

-4.71

Q12469

RLAPSAPATK

14.83

-3.56

-2.39

LAPSAPATKN

17.60

-2.75

-1.58

PSAPATKNHD

17.98

-3.85

-2.68

 


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