ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-20.PDB
Scoring matrix: NBP2_1GCQ-20_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.93
Foldx random average score for Saccharomyces cerevisiae: 14.455

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 883445
Proteins after disorder filtering: 3062
 Total fragments: 45898
Proteins after pattern filtering: 1338
 Total fragments: 5026
Proteins after MINT filtering: 6
 Total fragments: 62


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.93

-3.29

0.00

Best peptides

RRPFPGRHW

0.00

-8.21

-4.92

         
Interactors      
Q01389

YPQTPSYYY

7.05

-6.18

-2.89

KRSKPLPPQ

9.51

-9.99

-6.70

RPVPPDSSY

9.81

-10.35

-7.06

P53933

PPPIPSTQK

11.53

-6.14

-2.85

VAPPPLPNR

14.30

-5.86

-2.57

P48562

NPYRPHHNM

7.85

-10.76

-7.47

MRQAPKRPD

10.82

-6.95

-3.66

GQFPRGPMH

11.12

-4.74

-1.45

Q03497

KPSKPEAKS

10.19

-7.06

-3.77

HKPKVKPSK

10.97

-6.89

-3.60

KKSFPSKNP

11.31

-9.35

-6.06

P08018

APRRPLSTQ

10.11

-8.18

-4.89

TRPNVAPHK

10.65

-6.48

-3.19

PRLPSDKFS

11.75

-6.12

-2.83

Q12469

LKPFPRPSD

10.15

-6.35

-3.06

PFPRPSDDD

13.24

-5.53

-2.24

RLAPSAPAT

13.44

-6.71

-3.42

 


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