ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-19.PDB
Scoring matrix: NBP2_1GCQ-19_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.35
Foldx random average score for Saccharomyces cerevisiae: 15.733

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 908193
Proteins after disorder filtering: 3083
 Total fragments: 43822
Proteins after pattern filtering: 1429
 Total fragments: 6217
Proteins after MINT filtering: 6
 Total fragments: 72


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.35

-0.08

0.00

Best peptides

RRSKMGFHW

0.00

-3.37

-3.29

         
Interactors      
Q01389

RPVPPDSSY

8.66

-7.24

-7.16

KRSKPLPPQ

8.94

-6.25

-6.17

RRYPQTPSY

9.00

-6.71

-6.63

P53933

PPPIPSTQK

13.64

-6.13

-6.05

RRRPPPPPI

14.42

-9.56

-9.48

PPLPNRQLP

14.45

-7.96

-7.88

P48562

RQAPKRPDA

11.24

-3.09

-3.01

NPYRPHHNM

12.17

-6.53

-6.45

GVAKPKKPA

12.24

-4.27

-4.19

Q03497

KKSFPSKNP

10.05

-8.90

-8.82

KPSKPEAKS

10.18

-4.68

-4.60

KQHKPKVKP

11.04

-8.30

-8.22

P08018

PRLPSDKFS

12.23

-3.19

-3.11

PRRPLSTQH

12.36

-3.57

-3.49

APRRPLSTQ

12.51

-5.48

-5.40

Q12469

HRLAPSAPA

13.35

-4.29

-4.21

RLAPSAPAT

13.57

-5.00

-4.92

LKPFPRPSD

14.69

-5.63

-5.55

 


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