ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-16.PDB
Scoring matrix: NBP2_1GCQ-16_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.91
Foldx random average score for Saccharomyces cerevisiae: 22.060

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 1015951
Proteins after disorder filtering: 3247
 Total fragments: 91249
Proteins after pattern filtering: 1606
 Total fragments: 12277
Proteins after MINT filtering: 7
 Total fragments: 133


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.91

2.76

0.00

Best peptides

FHRLKSREG

0.00

-2.39

-5.15

         
Interactors      
Q01389

KSASPPASP

14.48

0.13

-2.63

APTKPNPQG

14.62

-3.26

-6.02

SGRRYPQTP

15.16

-3.85

-6.61

P53933

YNDLPMELP

13.53

-2.43

-5.19

RRPPPPPIP

14.60

-4.13

-6.89

TRRRPPPPP

15.04

-6.40

-9.16

P48562

QFPRGPMHP

10.98

-2.98

-5.74

PSPLNPYRP

12.20

-4.60

-7.36

TAPKPPISA

12.54

-4.05

-6.81

Q03497

GKFIPSRPA

9.54

-3.33

-6.09

KKSFPSKNP

11.88

-2.93

-5.69

KQHKPKVKP

12.34

-4.09

-6.85

Q12469

PHRLAPSAP

13.15

-1.79

-4.55

HRLAPSAPA

14.93

-0.46

-3.22

PFPRPSDDD

15.34

0.04

-2.72

P25293

NAPTPHNTP

14.31

-0.42

-3.18

APTPHNTPA

19.87

-1.05

-3.81

PTPHNTPAS

21.79

1.03

-1.73

P08018

QHPTRPNVA

11.64

-1.98

-4.74

LSTQHPTRP

14.68

-3.68

-6.44

HPTRPNVAP

14.97

-2.89

-5.65

 


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