ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-14.PDB
Scoring matrix: NBP2_1GCQ-14_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.06
Foldx random average score for Saccharomyces cerevisiae: 15.514

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 969335
Proteins after disorder filtering: 2916
 Total fragments: 39372
Proteins after pattern filtering: 1338
 Total fragments: 5196
Proteins after MINT filtering: 7
 Total fragments: 73


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.06

-2.52

0.00

Best peptides

IHKRIHKHR

0.00

-9.74

-7.22

         
Interactors      
Q01389

SPSYPSIFR

9.36

-6.49

-3.97

TPSRPVPPD

12.05

-9.28

-6.76

KRSKPLPPQ

12.31

-6.55

-4.03

P53933

VAPPPLPNR

12.48

-6.98

-4.46

PPPIPSTQK

13.26

-8.44

-5.92

PPPLPNRQL

13.62

-7.39

-4.87

P48562

NPYRPHHNM

3.98

-12.48

-9.96

APKRPDADV

8.98

-10.13

-7.61

PKPPISAPR

12.12

-7.87

-5.35

Q03497

HKPKVKPSK

12.33

-6.07

-3.55

FPSKNPLKN

12.79

-6.91

-4.39

LPPIPPTKS

13.28

-9.04

-6.52

Q12469

PFPRPSDDD

10.30

-9.30

-6.78

LKPFPRPSD

14.81

-3.61

-1.09

HRLAPSAPA

14.87

-2.37

0.15

P25293

TPHNTPASV

13.33

-4.75

-2.23

P08018

APRRPLSTQ

8.33

-10.72

-8.20

RAPRRPLST

9.88

-6.15

-3.63

PPPRLPSDK

10.39

-10.38

-7.86

 


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