ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-10.PDB
Scoring matrix: NBP2_1GCQ-10_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.98
Foldx random average score for Saccharomyces cerevisiae: 14.919

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5078
 Total fragments: 915290
Proteins after disorder filtering: 3236
 Total fragments: 64060
Proteins after pattern filtering: 1622
 Total fragments: 11705
Proteins after MINT filtering: 7
 Total fragments: 140


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.98

-0.62

0.00

Best peptides

RPRKPRRP

0.00

-10.52

-9.90

         
Interactors      
Q01389

RPVPPDSS

7.25

-7.43

-6.81

KPLPPQLL

7.58

-5.65

-5.03

EPSTPSRP

8.78

-5.05

-4.43

P53933

RPPPPPIP

4.94

-9.16

-8.54

RVAPPPLP

6.08

-6.70

-6.08

RRRPPPPP

7.00

-8.38

-7.76

P48562

MRQAPKRP

6.88

-7.13

-6.51

SPLNPYRP

7.76

-5.67

-5.05

FPRGPMHP

8.66

-5.06

-4.44

Q03497

GKFIPSRP

6.53

-5.36

-4.74

PKVKPSKP

7.34

-5.43

-4.81

KPSKPEAK

7.40

-5.84

-5.22

Q12469

PFPRPSDD

10.48

-3.64

-3.02

HRLAPSAP

10.87

-3.99

-3.37

APSAPATK

11.02

-3.53

-2.91

P25293

PHNTPASV

13.12

-3.19

-2.57

APTPHNTP

14.12

-1.45

-0.83

TPHNTPAS

14.38

-1.83

-1.21

P08018

APRRPLST

7.83

-5.14

-4.52

PPRLPSDK

8.55

-5.01

-4.39

HPTRPNVA

8.69

-5.09

-4.47

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER