ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-1.PDB
Scoring matrix: NBP2_1GCQ-1_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 24.93
Foldx random average score for Saccharomyces cerevisiae: 21.152

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 1369385
Proteins after disorder filtering: 3173
 Total fragments: 85280
Proteins after pattern filtering: 1601
 Total fragments: 15981
Proteins after MINT filtering: 7
 Total fragments: 185


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

24.93

0.50

0.00

Best peptides

FRRHRWRRRF

0.00

-8.11

-8.61

         
Interactors      
Q01389

KRSKPLPPQL

12.26

-10.83

-11.33

GRRYPQTPSY

14.23

-6.52

-7.02

PSSSPPPIPK

14.79

-5.41

-5.91

P53933

VRTRRRPPPP

11.31

-10.81

-11.31

TRRRPPPPPI

11.75

-8.88

-9.38

RRRPPPPPIP

12.16

-7.34

-7.84

P48562

FQNIGPAPRP

12.45

-9.73

-10.23

QTMRQAPKRP

13.16

-10.06

-10.56

MRQAPKRPDA

13.40

-12.08

-12.58

Q03497

HKQHKPKVKP

12.09

-8.81

-9.31

HKPKVKPSKP

12.74

-5.28

-5.78

FIPSRPAPKP

13.90

-9.74

-10.24

Q12469

ELKPFPRPSD

15.82

-5.79

-6.29

LKPFPRPSDD

16.58

-7.19

-7.69

RLAPSAPATK

17.32

-5.25

-5.75

P25293

PTPHNTPASV

18.72

-5.28

-5.78

DNAPTPHNTP

20.82

-2.68

-3.18

P08018

PLSTQHPTRP

12.40

-11.42

-11.92

STQHPTRPNV

14.63

-7.93

-8.43

IVDGPPPRLP

15.68

-10.31

-10.81

 


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