ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1ZUY-9.PDB
Scoring matrix: MYO5_1ZUY-9_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.76
Foldx random average score for Saccharomyces cerevisiae: 9.520

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3213509
Proteins after random average filtering: 7178
 Total fragments: 1992711
Proteins after disorder filtering: 4738
 Total fragments: 81762
Proteins after pattern filtering: 2036
 Total fragments: 6660
Proteins after MINT filtering: 41
 Total fragments: 302

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.76

0.43

0.00

Best peptides

RKWIPPWS

0.00

-5.50

-5.93

         
Interactors      
P53145

NEPLLPPL

7.00

-6.08

-6.51

LLPPLPGQ

7.72

-3.67

-4.10

PLLPPLPG

7.79

-4.12

-4.55

P39113

RGPRRPQK

6.17

-4.92

-5.35

GAPPPPPH

9.13

-4.29

-4.72

PRRPQKNR

9.37

-2.46

-2.89

P40073

PQQQPSHT

6.95

-4.39

-4.82

GYPQQQPS

8.95

-2.82

-3.25

P25604

PKPKSPHL

4.68

-3.84

-4.27

PLPPKPKS

6.59

-4.58

-5.01

QAPSLPPK

8.76

-3.31

-3.74

P25623

PKTVPISI

7.02

-4.50

-4.93

PLPVEPAS

7.44

-3.23

-3.66

PSEVPPST

8.01

-3.68

-4.11

Q05933

FRGPAYPS

8.53

-2.72

-3.15

TFPVDPNT

9.01

-2.69

-3.12

RGPAYPSN

9.05

-2.47

-2.90

P38822

PEVPPPRR

6.41

-6.39

-6.82

Q12451

LLPWLPPT

6.32

-3.90

-4.33

PKHAPPPV

7.97

-4.28

-4.71

HAPPPVPN

8.93

-4.61

-5.04

P15891

KEPVKTPS

6.38

-4.55

-4.98

PEKKPKEN

7.35

-6.62

-7.05

AAPPPPPR

8.33

-5.04

-5.47

P48562

KQPQSPLS

5.06

-4.94

-5.37

TAPKPPIS

6.13

-5.84

-6.27

PAPRPPSS

6.26

-4.79

-5.22

P40341

NDPSNPVS

8.98

-1.38

-1.81

Q08912

YTPSWGPS

6.80

-1.95

-2.38

P17555

PRPKKPST

7.55

-3.61

-4.04

PKKPSTLK

8.54

-3.06

-3.49

Q12342

LETPSTPS

8.32

-1.55

-1.98

P47068

PSSNPFFR

6.94

-4.37

-4.80

PEPISPET

6.95

-2.88

-3.31

PLPRAPPV

7.74

-4.58

-5.01

P04050

YSPTSPNY

5.95

-3.74

-4.17

YSPTSPSY

7.01

-3.57

-4.00

YSPTSPAY

7.08

-3.41

-3.84

P40450

PKLFPRLS

5.46

-4.51

-4.94

AAPAPPPL

8.08

-4.09

-4.52

SSPKLFPR

8.25

-3.85

-4.28

P40453

PSWKPPDL

5.70

-4.38

-4.81

KVPEPPSW

7.55

-4.49

-4.92

WKPPDLPI

8.50

-2.77

-3.20

Q12168

PVPKPNID

7.03

-5.97

-6.40

PYFPQFRS

7.28

-3.47

-3.90

DDPYFPQF

7.82

-2.61

-3.04

P41832

ETPPPPPL

8.81

-2.22

-2.65

PAPPMMPA

9.13

-3.27

-3.70

P36006

KKPKNPGG

6.51

-4.29

-4.72

GQPKDPKF

7.54

-4.66

-5.09

PKNPGGLS

9.07

-3.19

-3.62

P38753

PSNLPIQH

7.88

-5.53

-5.96

PVMPPQRQ

7.91

-3.72

-4.15

PVPGPALY

7.92

-4.61

-5.04

P38237

PFVPPPNV

7.73

-3.47

-3.90

FQIPSKPE

8.65

-3.06

-3.49

QIPSKPEN

9.23

-3.22

-3.65

P34245

FGPWPGPA

7.41

-3.76

-4.19

YSTPFGPW

7.72

-2.80

-3.23

PWPGPAEC

9.29

-3.07

-3.50

Q01389

SRPVPPDS

5.54

-3.79

-4.22

SKPLPPQL

6.25

-6.29

-6.72

ASPTSPKS

6.79

-2.72

-3.15

Q03306

RLPNSAPS

5.63

-3.40

-3.83

PFRIPSST

7.13

-4.08

-4.51

PSSPPPIS

7.38

-4.21

-4.64

P34758

QLPLEPLK

6.12

-5.67

-6.10

LEPLKPTA

6.59

-5.49

-5.92

LQPLKPTA

6.75

-4.91

-5.34

P53933

RRPPPPPI

5.29

-5.36

-5.79

DLPMELPH

7.82

-3.72

-4.15

VAPPPLPN

9.04

-3.63

-4.06

P32381

TEPPMNPL

9.30

-3.77

-4.20

Q00453

YFPHPMPS

5.08

-5.72

-6.15

SAPIPLPH

7.26

-4.86

-5.29

NLPISTPA

7.43

-3.72

-4.15

P40021

PLPPPARS

5.32

-5.85

-6.28

ISPNLPTT

8.25

-2.43

-2.86

FLPSTPSQ

9.04

-2.42

-2.85

Q12446

PLPQLPNR

6.55

-4.70

-5.13

SAPIPPTL

6.81

-4.95

-5.38

PFPVPQQQ

6.91

-5.62

-6.05

Q01560

YYPPPPPG

5.51

-6.62

-7.05

QEPQVPQE

7.95

-4.31

-4.74

PSNAPIYE

8.48

-3.69

-4.12

P00950

FDVPPPPI

6.61

-3.99

-4.42

DVPPPPID

8.48

-3.82

-4.25

P53735

LVPPPPRT

5.62

-5.05

-5.48

KLVPPPPR

6.66

-5.45

-5.88

P33334

LDNPMVPS

7.35

-2.04

-2.47

FDPSLNPI

7.64

-3.33

-3.76

GLPPPPPG

7.89

-5.33

-5.76

P40523

PLAPPPHG

5.91

-4.41

-4.84

PVGVPPLA

6.35

-5.87

-6.30

PLASPTHY

7.02

-3.54

-3.97

P40563

PSERPKRR

5.38

-5.46

-5.89

RAPPPVPK

6.90

-5.23

-5.66

VTPKVPER

8.61

-1.51

-1.94

P53094

KLPPLPLT

6.05

-4.61

-5.04

LKLPPLPL

6.27

-3.58

-4.01

AFPQSPIR

7.20

-4.02

-4.45

P37370

QMPKPRPF

5.48

-6.13

-6.56

PKPRPFQN

6.05

-5.34

-5.77

KSPPPPPS

6.49

-4.40

-4.83

Q03900

PSGAPKLK

8.16

-3.91

-4.34

HLPNTPSG

8.79

-2.83

-3.26

 


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