ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1ZUY-4.PDB
Scoring matrix: MYO5_1ZUY-4_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.17
Foldx random average score for Saccharomyces cerevisiae: 18.692

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1357823
Proteins after disorder filtering: 4362
 Total fragments: 78553
Proteins after pattern filtering: 2257
 Total fragments: 19769
Proteins after MINT filtering: 44
 Total fragments: 1360

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.17

-1.88

0.00
Best peptides

HKPRRFRDRW

0.00

-2.49

-0.61
         
Interactors      
P53145

NEPLLPPLPG

14.03

-4.11

-2.23

PLPGQPPLIN

14.07

-6.78

-4.90

PPLPGQPPLI

14.10

-6.33

-4.45
P39113

HRGPRRPQKN

10.36

-5.42

-3.54

ASHRGPRRPQ

11.54

-3.74

-1.86

SHRGPRRPQK

12.21

-4.39

-2.51
P40073

QFDGYPQQQP

17.20

-2.33

-0.45

FDGYPQQQPS

18.08

-1.42

0.46

GYPQQQPSHT

18.59

-3.38

-1.50
P25604

LKPPLPPPPP

8.77

-5.66

-3.78

NTPPLPPKPK

11.88

-5.02

-3.14

LPPPPPPQPA

12.00

-6.67

-4.79
P25623

LPKTVPISIS

13.60

-6.51

-4.63

KTKPLPVEPA

13.88

-3.30

-1.42

DTPPLPPHAT

14.59

-3.44

-1.56
Q05933

TKFRGPAYPS

10.53

-3.06

-1.18

FRGPAYPSNS

12.37

-5.64

-3.76

FPVDPNTDRM

13.88

-6.60

-4.72
P53094

FKSSAFPQSP

10.62

-6.15

-4.27

YPLKLPPLPL

12.47

-6.56

-4.68

LNVPLPPQTR

12.86

-4.52

-2.64
Q12451

PKHAPPPVPN

11.29

-5.75

-3.87

QPHLLPWLPP

12.63

-6.09

-4.21

APKHAPPPVP

13.48

-8.00

-6.12
P15891

APPPPPRRAT

12.19

-4.56

-2.68

PPPPPRRATP

12.92

-7.76

-5.88

SAAPPPPPRR

13.75

-4.19

-2.31
P48562

QFPRGPMHPN

9.52

-4.11

-2.23

SPLNPYRPHH

11.58

-5.76

-3.88

QPQRTAPKPP

11.87

-7.95

-6.07
P40341

PPPPPPPPPK

11.18

-8.25

-6.37

NNSRNIPPPP

12.69

1.16

3.04

NIPPPPPPPP

12.75

-7.11

-5.23
Q08912

PKGPPPPPPP

10.89

-7.25

-5.37

HPKGPPPPPP

11.27

-7.97

-6.09

PPPPPPPDEK

11.97

-7.43

-5.55
P17555

SKSGPPPRPK

10.17

-5.08

-3.20

KSGPPPRPKK

12.67

-3.84

-1.96

PRPKKPSTLK

12.83

-4.55

-2.67
Q12342

RKAKAPPPPP

10.53

-6.46

-4.58

AKAPPPPPPP

10.78

-6.06

-4.18

APPPPPPPPP

12.60

-7.65

-5.77
P47068

PLPRAPPVPP

11.26

-6.13

-4.25

DPSSNPFFRK

12.47

-4.36

-2.48

TAPPLPRAPP

12.77

-4.17

-2.29
P38822

PAPEVPPPRR

13.91

-5.14

-3.26

APEVPPPRRS

14.08

-5.40

-3.52

DRGPAPEVPP

15.15

-5.44

-3.56
P04050

LPVPPPPVRP

12.11

-6.19

-4.31

CLPVPPPPVR

13.52

-5.00

-3.12

PPPPVRPSIS

14.12

-7.30

-5.42
P40450

LPPPPPPPPP

11.27

-9.29

-7.41

LPQLPPPPPP

12.04

-9.13

-7.25

PPPPPPPLPQ

12.41

-8.15

-6.27
P40453

LRKRPPPPPP

7.48

-7.73

-5.85

RKRPPPPPPV

10.57

-5.76

-3.88

TKVPEPPSWK

11.14

-4.00

-2.12
Q12168

NRGPPPLPPR

11.81

-5.89

-4.01

DNDDPYFPQF

12.14

-5.29

-3.41

NKVQHPVPKP

12.25

-5.12

-3.24
P41832

PPPPPPPPPM

11.56

-7.89

-6.01

QPPPPPPPPP

11.68

-7.34

-5.46

PPPPPPMALF

11.73

-8.52

-6.64
P36006

PPPPPPMGQP

12.50

-8.27

-6.39

PKDPKFEAAY

12.96

-5.18

-3.30

PPMGQPKDPK

13.02

-7.75

-5.87
P38753

NTPVMPPQRQ

12.80

-2.87

-0.99

YPSNLPIQHP

14.24

-5.78

-3.90

NNTPVMPPQR

14.62

-5.47

-3.59
P38237

FVPPPNVPKK

13.43

-5.03

-3.15

DLNDPFVPPP

14.42

-4.55

-2.67

DPFVPPPNVP

14.77

-6.98

-5.10
P34245

STPFGPWPGP

15.88

-2.86

-0.98

AYSTPFGPWP

16.28

-4.69

-2.81

PFGPWPGPAE

16.80

-1.42

0.46
Q01389

APKREAPKPP

12.49

-7.91

-6.03

PKREAPKPPA

13.10

-5.75

-3.87

PASPSYPSIF

13.53

-6.19

-4.31
Q03306

TKPNVPPLQT

11.57

-3.21

-1.33

KPFRIPSSTK

11.63

-5.97

-4.09

QPTPSPPLPQ

12.32

-6.54

-4.66
P34758

PPPPPPRAQQ

11.28

-5.89

-4.01

LPPPPPPRAQ

11.50

-7.42

-5.54

QPQHLPPPPP

11.60

-6.67

-4.79
P53933

TRRRPPPPPI

7.71

-5.29

-3.41

RTRRRPPPPP

10.26

-7.18

-5.30

VRTRRRPPPP

10.69

-6.07

-4.19
P32381

LLTEPPMNPL

13.44

-5.63

-3.75
Q00453

YAPPYFPHPM

11.02

-5.01

-3.13

LPHQPPPLPI

12.12

-6.73

-4.85

FPHPMPSAPI

12.33

-4.29

-2.41
P40021

PPPPLPPPLF

11.93

-7.76

-5.88

LPPPLFPSSS

12.60

-7.11

-5.23

TKNTGPPPPL

12.82

-4.61

-2.73
P36150

PIVVNPSSPS

16.55

-4.48

-2.60

NPIVVNPSSP

17.28

-4.64

-2.76
Q12446

HKAPPPPPPT

9.22

-4.73

-2.85

NRPVPPPPPM

9.98

-5.82

-3.94

TKHKAPPPPP

10.68

-5.18

-3.30
Q01560

QPYYPPPPPG

11.53

-7.71

-5.83

YYPPPPPGEH

12.09

-7.28

-5.40

PQPYYPPPPP

12.27

-4.96

-3.08
P00950

DVPPPPIDAS

14.09

-4.29

-2.41

RSFDVPPPPI

14.41

-4.06

-2.18

RRSFDVPPPP

14.82

-3.40

-1.52
P53735

PKLVPPPPRT

10.99

-5.21

-3.33

LVPPPPRTRS

11.62

-3.75

-1.87

APKLVPPPPR

12.73

-7.78

-5.90
P33334

MPTRFPPAVF

8.86

-6.48

-4.60

SKMPTRFPPA

11.44

-3.46

-1.58

LPPPPPPPPG

11.48

-7.71

-5.83
P40523

YMHNSPRNPD

12.15

-4.91

-3.03

LPTPVPVPVG

13.77

-5.52

-3.64

GVPPLAPPPH

14.02

-6.53

-4.65
P40563

PKRRAPPPVP

8.66

-6.50

-4.62

KRRAPPPVPK

10.36

-6.76

-4.88

RRAPPPVPKK

11.37

-4.99

-3.11
Q08989

PKGPPPPPPP

10.89

-7.25

-5.37

HPKGPPPPPP

11.27

-7.97

-6.09

PPPPPPPDEK

11.97

-7.43

-5.55
P37370

PKPRPFQNKT

9.90

-7.85

-5.97

LPPSAPPPPI

10.64

-7.38

-5.50

HKSPSQPPLP

10.93

-6.23

-4.35
P39743

PNATIPEDNP

17.07

-4.63

-2.75

PAYSNPLTSP

18.64

-3.85

-1.97
Q03900

HLPNTPSGAP

14.50

-3.84

-1.96

NTPSGAPKLK

15.33

-3.79

-1.91

TPSGAPKLKN

15.37

-4.12

-2.24

 


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