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Matrix information:
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ADAN-name: MYO5_1ZUY-3.PDB
Scoring matrix: MYO5_1ZUY-3_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.18
Foldx random average score for Saccharomyces cerevisiae: 17.409 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3199153
Proteins after random average filtering: 7177
Total fragments: 1400560
Proteins after disorder filtering: 4505
Total fragments: 85445
Proteins after pattern filtering: 2288
Total fragments: 16680
Proteins after MINT filtering: 44
Total fragments: 1011 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
18.18
|
4.90 |
0.00 |
| Best peptides |
PKKRKFWPMR |
0.00
|
-0.77 |
-5.67 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PLLPPLPGQP |
13.32
|
-5.39 |
-10.29 |
|
PNEPLLPPLP |
13.65
|
-4.66 |
-9.56 |
|
PPLPGQPPLI |
14.05
|
-5.59 |
-10.49 |
| P39113 |
PLGAPPPPPH |
8.47
|
-5.18 |
-10.08 |
|
SHRGPRRPQK |
9.73
|
-4.85 |
-9.75 |
|
SPLGAPPPPP |
9.96
|
-7.67 |
-12.57 |
| P40073 |
QFDGYPQQQP |
13.98
|
-5.67 |
-10.57 |
| P25604 |
PHLKPPLPPP |
8.44
|
-6.59 |
-11.49 |
|
PKSPHLKPPL |
10.82
|
-3.38 |
-8.28 |
|
PKPKSPHLKP |
11.11
|
-5.95 |
-10.85 |
| P25623 |
PPHATPKNVD |
10.88
|
-6.74 |
-11.64 |
|
SKTKPLPVEP |
11.06
|
-4.87 |
-9.77 |
|
PPLPPHATPK |
12.35
|
-5.80 |
-10.70 |
| Q05933 |
TKFRGPAYPS |
11.12
|
-3.75 |
-8.65 |
|
FRGPAYPSNS |
14.03
|
-3.56 |
-8.46 |
|
PGTPGFPLNN |
14.16
|
-3.57 |
-8.47 |
| P53094 |
PQTREPNEPP |
8.39
|
-4.92 |
-9.82 |
|
YPLKLPPLPL |
11.29
|
-6.11 |
-11.01 |
|
FKSSAFPQSP |
11.59
|
-4.43 |
-9.33 |
| Q12451 |
APKHAPPPVP |
9.89
|
-8.08 |
-12.98 |
|
PKHAPPPVPN |
10.02
|
-4.79 |
-9.69 |
|
QPHLLPWLPP |
12.48
|
-8.77 |
-13.67 |
| P15891 |
PRRATPEKKP |
8.55
|
-6.42 |
-11.32 |
|
RSSAAPPPPP |
11.09
|
-6.56 |
-11.46 |
|
RRATPEKKPK |
11.46
|
-4.65 |
-9.55 |
| P48562 |
PPISAPRAPY |
9.97
|
-6.51 |
-11.41 |
|
PTNGQFPRGP |
10.06
|
-4.80 |
-9.70 |
|
PYSKQPQSPL |
10.27
|
-4.20 |
-9.10 |
| P40341 |
SRNIPPPPPP |
11.69
|
-5.80 |
-10.70 |
|
RNIPPPPPPP |
11.98
|
-6.87 |
-11.77 |
|
PPLNDPSNPV |
12.61
|
-5.78 |
-10.68 |
| Q08912 |
PKGPPPPPPP |
7.94
|
-6.30 |
-11.20 |
|
HPKGPPPPPP |
9.27
|
-8.00 |
-12.90 |
|
THGDHPKGPP |
11.51
|
-6.01 |
-10.91 |
| P17555 |
SKSGPPPRPK |
9.19
|
-4.67 |
-9.57 |
|
RPKKPSTLKT |
11.74
|
-4.49 |
-9.39 |
|
PPRPKKPSTL |
11.83
|
-5.76 |
-10.66 |
| Q12342 |
RKAKAPPPPP |
5.79
|
-6.51 |
-11.41 |
|
AKAPPPPPPP |
11.07
|
-5.42 |
-10.32 |
|
KAKAPPPPPP |
11.58
|
-6.76 |
-11.66 |
| P47068 |
MPNTAPPLPR |
10.27
|
-7.03 |
-11.93 |
|
PPALSAPSVP |
10.68
|
-6.42 |
-11.32 |
|
PLPRAPPVPP |
11.02
|
-6.28 |
-11.18 |
| P38822 |
DRGPAPEVPP |
12.96
|
-4.33 |
-9.23 |
|
APEVPPPRRS |
13.94
|
-6.57 |
-11.47 |
|
PAPEVPPPRR |
14.93
|
-5.64 |
-10.54 |
| P04050 |
PPVRPSISFN |
10.83
|
-3.66 |
-8.56 |
|
SPSYSPTSPG |
13.35
|
-4.53 |
-9.43 |
|
LPVPPPPVRP |
13.49
|
-8.40 |
-13.30 |
| P40450 |
PQLPPPPPPP |
11.29
|
-5.94 |
-10.84 |
|
TCGAVPPPPP |
12.25
|
-6.05 |
-10.95 |
|
SPKLFPRLSS |
12.91
|
-4.37 |
-9.27 |
| P40453 |
RLRKRPPPPP |
6.37
|
-7.65 |
-12.55 |
|
LRKRPPPPPP |
7.00
|
-7.46 |
-12.36 |
|
PPSWKPPDLP |
7.60
|
-7.70 |
-12.60 |
| Q12168 |
TTNRGPPPLP |
10.67
|
-7.96 |
-12.86 |
|
TNRGPPPLPP |
11.55
|
-6.84 |
-11.74 |
|
NKVQHPVPKP |
12.38
|
-6.91 |
-11.81 |
| P41832 |
PKGETPPPPP |
7.79
|
-6.28 |
-11.18 |
|
VLSSQPPPPP |
11.53
|
-6.64 |
-11.54 |
|
SPAPPPPPPP |
12.02
|
-8.14 |
-13.04 |
| P36006 |
PPMGQPKDPK |
6.96
|
-7.09 |
-11.99 |
|
PKDPKFEAAY |
10.15
|
-3.56 |
-8.46 |
|
SKSNKKPKNP |
11.31
|
-4.03 |
-8.93 |
| P38753 |
YPSNLPIQHP |
13.38
|
-5.66 |
-10.56 |
|
PPVPGPALYA |
13.69
|
-4.59 |
-9.49 |
|
AHISPPVPGP |
13.73
|
-5.13 |
-10.03 |
| P38237 |
DLNDPFVPPP |
12.64
|
-4.73 |
-9.63 |
|
PFVPPPNVPK |
13.93
|
-4.51 |
-9.41 |
|
DPFVPPPNVP |
13.93
|
-7.39 |
-12.29 |
| P34245 |
PFGPWPGPAE |
13.16
|
-4.77 |
-9.67 |
|
TPFGPWPGPA |
13.47
|
-5.29 |
-10.19 |
|
AYSTPFGPWP |
14.22
|
-4.44 |
-9.34 |
| Q01389 |
APKREAPKPP |
8.57
|
-7.34 |
-12.24 |
|
PKREAPKPPA |
9.27
|
-4.82 |
-9.72 |
|
KRSKPLPPQL |
10.19
|
-3.54 |
-8.44 |
| Q03306 |
PRTKPNVPPL |
8.72
|
-2.85 |
-7.75 |
|
RNKSIPRTKP |
10.22
|
-6.76 |
-11.66 |
|
MNGRLPNSAP |
10.45
|
-5.69 |
-10.59 |
| P34758 |
PQHLPPPPPP |
10.10
|
-6.30 |
-11.20 |
|
QPQHLPPPPP |
13.21
|
-8.15 |
-13.05 |
|
QHLPPPPPPR |
13.28
|
-5.82 |
-10.72 |
| P53933 |
RTRRRPPPPP |
7.14
|
-6.98 |
-11.88 |
|
VRTRRRPPPP |
7.65
|
-6.89 |
-11.79 |
|
TRRRPPPPPI |
8.40
|
-6.34 |
-11.24 |
| P32381 |
LLTEPPMNPL |
14.07
|
-6.44 |
-11.34 |
|
ILLTEPPMNP |
14.35
|
-6.07 |
-10.97 |
| Q00453 |
PPYFPHPMPS |
11.50
|
-5.91 |
-10.81 |
|
PYFPHPMPSA |
13.23
|
-4.81 |
-9.71 |
|
PLPHQPPPLP |
13.40
|
-5.43 |
-10.33 |
| P40021 |
KNTGPPPPLP |
10.87
|
-6.08 |
-10.98 |
|
TKNTGPPPPL |
11.65
|
-5.73 |
-10.63 |
|
PTKNTGPPPP |
12.57
|
-3.07 |
-7.97 |
| P36150 |
NPIVVNPSSP |
15.74
|
-5.72 |
-10.62 |
|
PIVVNPSSPS |
16.26
|
-3.76 |
-8.66 |
| Q12446 |
PPRRGPAPPP |
5.92
|
-8.14 |
-13.04 |
|
PRRGPAPPPP |
7.33
|
-4.87 |
-9.77 |
|
TKHKAPPPPP |
8.03
|
-6.87 |
-11.77 |
| Q01560 |
PPEPQPYYPP |
10.98
|
-7.13 |
-12.03 |
|
PQESAPQEPP |
11.98
|
-4.95 |
-9.85 |
|
PQAPDAPQEP |
12.56
|
-4.38 |
-9.28 |
| P00950 |
RRSFDVPPPP |
12.54
|
-5.96 |
-10.86 |
|
RSFDVPPPPI |
13.79
|
-4.32 |
-9.22 |
|
SFDVPPPPID |
16.78
|
-5.89 |
-10.79 |
| P53735 |
APKLVPPPPR |
9.31
|
-6.53 |
-11.43 |
|
PKLVPPPPRT |
10.64
|
-4.60 |
-9.50 |
|
KLVPPPPRTR |
12.42
|
-6.46 |
-11.36 |
| P33334 |
MPTRFPPAVF |
7.72
|
-7.50 |
-12.40 |
|
PGGPKFEPLY |
11.92
|
-2.35 |
-7.25 |
|
IPGGPKFEPL |
12.12
|
-5.15 |
-10.05 |
| P40523 |
PPHGPFSTSM |
9.86
|
-5.44 |
-10.34 |
|
PPLAPPPHGP |
10.72
|
-7.41 |
-12.31 |
|
PPGTVPNMQM |
10.86
|
-6.08 |
-10.98 |
| P40563 |
PKRRAPPPVP |
4.12
|
-7.52 |
-12.42 |
|
PSERPKRRAP |
9.61
|
-4.36 |
-9.26 |
|
RRAPPPVPKK |
10.66
|
-4.79 |
-9.69 |
| Q08989 |
PKGPPPPPPP |
7.94
|
-6.30 |
-11.20 |
|
HPKGPPPPPP |
9.27
|
-8.00 |
-12.90 |
|
GTNGDHPKGP |
12.78
|
-4.53 |
-9.43 |
| P37370 |
PQNRPHMPSV |
7.97
|
-3.99 |
-8.89 |
|
PLAPLPPPPP |
9.42
|
-6.65 |
-11.55 |
|
PTSHAPPLPP |
10.16
|
-5.01 |
-9.91 |
| P39743 |
PNATIPEDNP |
11.79
|
-4.84 |
-9.74 |
|
PAYSNPLTSP |
14.53
|
-5.30 |
-10.20 |
| Q03900 |
TPSGAPKLKN |
10.94
|
-6.73 |
-11.63 |
|
PSGAPKLKNY |
14.52
|
-2.39 |
-7.29 |
|
PNTPSGAPKL |
15.40
|
-1.61 |
-6.51 |
|
