ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1ZUY-2.PDB
Scoring matrix: MYO5_1ZUY-2_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.0
Foldx random average score for Saccharomyces cerevisiae: 19.796

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1345112
Proteins after disorder filtering: 4458
 Total fragments: 87891
Proteins after pattern filtering: 2291
 Total fragments: 20522
Proteins after MINT filtering: 44
 Total fragments: 1351

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.00

-3.35

0.00
Best peptides

WRPRMFRERW

0.00

1.29

4.64
         
Interactors      
P53145

NEPLLPPLPG

16.27

-2.78

0.57

PLPGQPPLIN

17.04

-6.15

-2.80

LLPPLPGQPP

17.34

-5.03

-1.68
P39113

ASHRGPRRPQ

11.83

-5.17

-1.82

HRGPRRPQKN

12.25

-4.97

-1.62

GPRRPQKNRY

12.26

-5.92

-2.57
P40073

QFDGYPQQQP

16.34

-4.26

-0.91

FDGYPQQQPS

16.95

-2.43

0.92
P25604

PKPKSPHLKP

12.22

-5.39

-2.04

PHLKPPLPPP

12.25

-6.71

-3.36

KPPLPPPPPP

12.89

-8.42

-5.07
P25623

AQTFTPSEVP

14.68

-5.59

-2.24

QPPLQPQSKT

15.61

-6.27

-2.92

ASDTPPLPPH

15.67

-5.56

-2.21
Q05933

TKFRGPAYPS

12.11

-4.82

-1.47

FRGPAYPSNS

12.22

-4.50

-1.15

FPVDPNTDRM

14.46

-5.64

-2.29
P53094

FKSSAFPQSP

11.54

-5.64

-2.29

YPLKLPPLPL

11.61

-6.55

-3.20

PQTREPNEPP

12.18

-7.04

-3.69
Q12451

QPHLLPWLPP

12.63

-7.91

-4.56

APKHAPPPVP

13.49

-7.53

-4.18

PKHAPPPVPN

14.53

-6.80

-3.45
P15891

PRRATPEKKP

12.69

-5.72

-2.37

KKSFTPSKSP

13.59

-2.29

1.06

SRSSAAPPPP

13.87

-4.87

-1.52
P48562

QPQRTAPKPP

11.08

-7.53

-4.18

QTMRQAPKRP

11.35

-4.28

-0.93

QFPRGPMHPN

11.90

-6.29

-2.94
P40341

SRNIPPPPPP

11.95

-6.29

-2.94

PPPPPPPPKP

13.30

-9.42

-6.07

PPPPPPPPPK

13.32

-9.07

-5.72
Q08912

DHPKGPPPPP

11.77

-5.68

-2.33

PKGPPPPPPP

12.21

-7.52

-4.17

HPKGPPPPPP

12.24

-9.03

-5.68
P17555

PRPKKPSTLK

12.90

-6.32

-2.97

SKSGPPPRPK

13.23

-6.12

-2.77

KSGPPPRPKK

13.36

-4.34

-0.99
Q12342

AKAPPPPPPP

12.25

-6.98

-3.63

RKAKAPPPPP

12.51

-6.22

-2.87

APPPPPPPPP

13.59

-8.62

-5.27
P47068

PLPRAPPVPP

11.03

-7.21

-3.86

DPSSNPFFRK

13.50

-5.27

-1.92

MPNTAPPLPR

13.51

-8.70

-5.35
P38822

DRGPAPEVPP

13.56

-4.82

-1.47

APEVPPPRRS

14.76

-6.58

-3.23

PAPEVPPPRR

15.20

-6.31

-2.96
P04050

LPVPPPPVRP

14.43

-8.61

-5.26

CLPVPPPPVR

15.32

-5.10

-1.75

PPVRPSISFN

15.36

-5.71

-2.36
P40450

QLPPPPPPPP

13.37

-6.05

-2.70

PPPPPPPPPP

13.39

-9.34

-5.99

PPPPPPPPPL

13.82

-8.36

-5.01
P40453

LRKRPPPPPP

8.06

-8.14

-4.79

IRLRKRPPPP

10.59

-2.51

0.84

KRPPPPPPVS

12.84

-5.84

-2.49
Q12168

NRGPPPLPPR

12.43

-5.59

-2.24

DNDDPYFPQF

12.99

-3.27

0.08

NKVQHPVPKP

13.78

-5.95

-2.60
P41832

QPPPPPPPPP

12.64

-8.05

-4.70

PKGETPPPPP

12.90

-6.86

-3.51

PPPPPPPPPP

13.39

-9.34

-5.99
P36006

PKDPKFEAAY

13.52

-4.07

-0.72

PPMGQPKDPK

13.90

-7.77

-4.42

ANIPIPPPPP

14.04

-6.47

-3.12
P38753

NTPVMPPQRQ

15.24

-2.62

0.73

YPSNLPIQHP

15.88

-7.31

-3.96

NNTPVMPPQR

16.07

-4.71

-1.36
P38237

DLNDPFVPPP

15.03

-4.85

-1.50

DPFVPPPNVP

15.15

-6.77

-3.42

PDLNDPFVPP

15.21

-4.71

-1.36
P34245

STPFGPWPGP

16.30

-4.08

-0.73

AYSTPFGPWP

16.36

-4.15

-0.80

GPWPGPAECL

17.54

-5.01

-1.66
Q01389

APKREAPKPP

11.82

-11.11

-7.76

GSGRRYPQTP

12.85

-5.37

-2.02

PKREAPKPPA

13.84

-4.95

-1.60
Q03306

KPFRIPSSTK

11.35

-5.28

-1.93

YRQPTPSPPL

11.47

-6.37

-3.02

MNGRLPNSAP

12.04

-4.93

-1.58
P34758

QPQHLPPPPP

11.77

-6.74

-3.39

QHLPPPPPPR

12.19

-5.64

-2.29

HLPPPPPPRA

13.14

-5.38

-2.03
P53933

TRRRPPPPPI

7.59

-6.19

-2.84

VRTRRRPPPP

9.51

-6.93

-3.58

RTRRRPPPPP

12.19

-8.21

-4.86
P32381

LLTEPPMNPL

16.72

-4.45

-1.10

ILLTEPPMNP

19.34

-2.74

0.61
Q00453

FPHPMPSAPI

12.73

-5.91

-2.56

APPYFPHPMP

13.26

-8.08

-4.73

YAPPYFPHPM

13.45

-5.77

-2.42
P40021

TKNTGPPPPL

13.45

-4.04

-0.69

PPPLPPPLFP

14.36

-8.41

-5.06

NTGPPPPLPP

14.71

-6.01

-2.66
P36150

PIVVNPSSPS

17.54

-4.15

-0.80

NPIVVNPSSP

17.66

-4.59

-1.24
Q12446

NRPVPPPPPM

11.15

-6.44

-3.09

TKHKAPPPPP

11.19

-5.59

-2.24

PPRRGPAPPP

11.20

-8.72

-5.37
Q01560

QPYYPPPPPG

12.57

-9.41

-6.06

PQPYYPPPPP

12.65

-6.06

-2.71

EPQPYYPPPP

12.91

-8.25

-4.90
P00950

FDVPPPPIDA

17.02

-2.40

0.95

SFDVPPPPID

17.38

-4.51

-1.16

RSFDVPPPPI

17.57

-3.91

-0.56
P53735

PKLVPPPPRT

12.68

-6.60

-3.25

APKLVPPPPR

13.87

-8.56

-5.21

KLVPPPPRTR

15.71

-4.64

-1.29
P33334

MPTRFPPAVF

9.00

-6.33

-2.98

FTLPPPPPPP

12.90

-6.68

-3.33

EDTFLPPPPP

13.93

-4.19

-0.84
P40523

YMHNSPRNPD

14.67

-3.67

-0.32

PPPHGPFSTS

15.52

-5.20

-1.85

PLAPPPHGPF

15.62

-4.53

-1.18
P40563

PKRRAPPPVP

8.86

-8.12

-4.77

KRRAPPPVPK

11.57

-6.61

-3.26

PSERPKRRAP

13.54

-6.04

-2.69
Q08989

DHPKGPPPPP

11.77

-5.68

-2.33

PKGPPPPPPP

12.21

-7.52

-4.17

HPKGPPPPPP

12.24

-9.03

-5.68
P37370

PKPRPFQNKT

9.64

-5.33

-1.98

NRPHMPSVRP

9.67

-4.04

-0.69

NPTKSPPPPP

11.99

-8.34

-4.99
P39743

PNATIPEDNP

16.33

-4.27

-0.92

PAYSNPLTSP

19.40

-5.13

-1.78
Q03900

HLPNTPSGAP

15.43

-4.30

-0.95

TPSGAPKLKN

16.04

-4.85

-1.50

PNTPSGAPKL

18.76

-2.51

0.84

 


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