ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1ZUY-19.PDB
Scoring matrix: MYO5_1ZUY-19_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.14
Foldx random average score for Saccharomyces cerevisiae: 20.428

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206331
Proteins after random average filtering: 7178
 Total fragments: 1467664
Proteins after disorder filtering: 4558
 Total fragments: 64451
Proteins after pattern filtering: 1992
 Total fragments: 6742
Proteins after MINT filtering: 38
 Total fragments: 250

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.14

3.12

0.00

Best peptides

AMKMWGRHY

0.00

-3.14

-6.26

         
Interactors      
P53145

PGQPPLINI

17.38

-5.92

-9.04

PLLPPLPGQ

18.09

-3.30

-6.42

PNEPLLPPL

19.53

-4.11

-7.23

P39113

AMSPLGAPP

14.51

-4.63

-7.75

PRRPQKNRY

15.81

-5.47

-8.59

ASHRGPRRP

17.61

-3.55

-6.67

P25604

QNTPPLPPK

18.28

-4.84

-7.96

QDQAPSLPP

19.10

-4.50

-7.62

HLKPPLPPP

19.30

-5.71

-8.83

P25623

PLQPQSKTK

18.33

-2.32

-5.44

PVEPASPSI

19.10

-3.28

-6.40

SDTPPLPPH

19.70

-2.92

-6.04

Q05933

PVDPNTDRM

17.54

-2.98

-6.10

PAYPSNSDY

18.28

-2.68

-5.80

FTLPGTPGF

19.17

-3.37

-6.49

P53094

PLPPQTREP

16.93

-3.63

-6.75

AKAPNTPST

17.74

-0.94

-4.06

DEDPVSPKP

18.65

-3.23

-6.35

Q12451

AAPKHAPPP

19.00

-4.11

-7.23

HLLPWLPPT

19.76

-4.11

-7.23

P15891

RRATPEKKP

16.27

-5.69

-8.81

AAQPPLPSR

16.89

-4.31

-7.43

ATPEKKPKE

17.06

-0.63

-3.75

P48562

PLNPYRPHH

13.26

-2.65

-5.77

GQFPRGPMH

15.69

-1.28

-4.40

MRQAPKRPD

16.23

-2.83

-5.95

P40341

PLNDPSNPV

20.36

-2.75

-5.87

Q08912

GDHPKGPPP

17.88

-5.08

-8.20

YTPSWGPSP

18.75

-2.56

-5.68

VCYTPSWGP

20.06

-2.70

-5.82

P17555

SGPPPRPKK

18.52

-3.89

-7.01

PKKPSTLKT

18.84

-2.05

-5.17

ATAAPAPPP

19.78

-4.44

-7.56

P47068

PISPETKKE

17.03

-0.65

-3.77

PSSNPFFRK

17.35

-1.25

-4.37

PLPPVSEEY

17.58

-1.47

-4.59

P38822

RGPAPEVPP

19.40

-4.54

-7.66

PEVPPPRRS

19.60

-3.07

-6.19

P04050

AYSPTSPSY

14.79

-1.98

-5.10

SYSPTSPGY

17.61

-2.01

-5.13

SYSPTSPNY

17.82

-3.28

-6.40

P40450

SSPKLFPRL

17.57

-3.19

-6.31

LVTPPAPPL

18.67

-4.72

-7.84

PAPPPLPDL

19.74

-4.45

-7.57

P40453

PDLPIRLRK

15.13

-2.90

-6.02

AWDCPRCGP

17.81

-4.08

-7.20

SWKPPDLPI

18.51

-3.68

-6.80

Q12168

NDDPYFPQF

18.14

-4.74

-7.86

RGPPPLPPR

18.62

-3.92

-7.04

QHPVPKPNI

18.92

-5.95

-9.07

P41832

GVIPPAPPM

19.66

-5.28

-8.40

P36006

MGQPKDPKF

14.46

-5.06

-8.18

PKNPGGLSG

18.10

-2.51

-5.63

PMGQPKDPK

19.28

-3.31

-6.43

P38753

PVMPPQRQS

17.00

-3.09

-6.21

PSNLPIQHP

19.24

-1.98

-5.10

P38237

NFQIPSKPE

19.03

0.98

-2.14

FVPPPNVPK

20.11

-2.20

-5.32

P34245

FGPWPGPAE

17.17

-1.50

-4.62

YSTPFGPWP

17.33

-3.80

-6.92

AYSTPFGPW

17.36

-1.24

-4.36

Q01389

RRYPQTPSY

16.15

-4.42

-7.54

ASPPASPSY

16.29

-2.56

-5.68

PSYPSIFRR

18.53

-2.91

-6.03

Q03306

PWGPNNRIN

14.70

-1.21

-4.33

GEEKPFRIP

14.81

-5.15

-8.27

ASSEPSSPP

18.37

-3.72

-6.84

P34758

HSQPNKPNY

17.72

-4.15

-7.27

QQLPLEPLK

18.15

-1.72

-4.84

IHSQPNKPN

18.35

-1.53

-4.65

P53933

NDLPMELPH

19.36

-1.86

-4.98

VAPPPLPNR

19.59

-4.03

-7.15

Q00453

YAPPYFPHP

14.98

-3.95

-7.07

SAPIPLPHQ

17.71

-1.62

-4.74

HQPPPLPIY

18.28

-3.50

-6.62

P40021

PLPPPARSQ

14.32

-4.32

-7.44

SHPPNHPHS

17.17

-0.48

-3.60

PSTPSQMNY

18.28

-3.96

-7.08

Q12446

PASPEVRKE

14.95

-1.30

-4.42

PPPPPHRHV

16.34

-1.98

-5.10

ALPPASPEV

17.30

-2.20

-5.32

Q01560

PQEPPAPQE

17.65

-2.29

-5.41

PQAPDAPQE

18.44

0.14

-2.98

PPPPPGEHM

18.80

-2.12

-5.24

P33334

PSLNPIPHF

15.35

-3.14

-6.26

NAIPGGPKF

15.65

-4.36

-7.48

PMVPSSVNE

16.60

-1.80

-4.92

P40523

LGAPPGTVP

17.48

-5.54

-8.66

LAPPPHGPF

18.08

-5.26

-8.38

PGTVPNMQM

18.92

-3.40

-6.52

P40563

PSERPKRRA

12.64

-2.50

-5.62

GMVNPGQLP

17.15

-4.93

-8.05

RAPPPVPKK

18.10

-4.27

-7.39

Q08989

GDHPKGPPP

17.88

-5.08

-8.20

P37370

KVPQNRPHM

14.55

-3.66

-6.78

PKVPQNRPH

15.13

-0.06

-3.18

VSQMPKPRP

16.42

-5.66

-8.78

P39743

AYSNPLTSP

18.52

-3.40

-6.52

YSNPLTSPV

20.06

-2.28

-5.40

Q03900

PNTPSGAPK

17.65

-1.63

-4.75

PSGAPKLKN

19.46

-0.84

-3.96

 


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