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Matrix information:
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ADAN-name: MYO5_1ZUY-15.PDB
Scoring matrix: MYO5_1ZUY-15_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.44
Foldx random average score for Saccharomyces cerevisiae: 12.368 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3206331
Proteins after random average filtering: 7178
Total fragments: 1481780
Proteins after disorder filtering: 4320
Total fragments: 43440
Proteins after pattern filtering: 1454
Total fragments: 3170
Proteins after MINT filtering: 34
Total fragments: 112 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
15.44
|
6.04 |
0.00 |
| Best peptides |
RGFIIWLIR |
0.00
|
-3.00 |
-9.04 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PGQPPLINI |
11.53
|
-1.46 |
-7.50 |
| P39113 |
RGPRRPQKN |
8.30
|
-3.07 |
-9.11 |
|
HRGPRRPQK |
9.61
|
0.95 |
-5.09 |
|
PRRPQKNRY |
12.05
|
0.46 |
-5.58 |
| P40073 |
GYPQQQPSH |
12.07
|
0.57 |
-5.47 |
| P25604 |
PKPKSPHLK |
11.06
|
-0.22 |
-6.26 |
|
KSPHLKPPL |
12.31
|
-1.02 |
-7.06 |
| P25623 |
PKTVPISIS |
12.24
|
-1.10 |
-7.14 |
| Q05933 |
RGPAYPSNS |
11.53
|
-0.37 |
-6.41 |
|
PGTPGFPLN |
11.97
|
0.29 |
-5.75 |
| Q12451 |
PWLPPTDTR |
11.88
|
-0.09 |
-6.13 |
| P15891 |
AAQPPLPSR |
9.01
|
-0.21 |
-6.25 |
|
RATPEKKPK |
10.59
|
-0.07 |
-6.11 |
|
AAPPPPPRR |
10.61
|
-1.50 |
-7.54 |
| P48562 |
RGPMHPNNS |
9.21
|
-1.97 |
-8.01 |
|
NGQFPRGPM |
9.90
|
-0.30 |
-6.34 |
|
RQAPKRPDA |
11.61
|
0.27 |
-5.77 |
| P40341 |
NDPSNPVSK |
9.83
|
1.31 |
-4.73 |
| Q08912 |
HGDHPKGPP |
11.85
|
-0.36 |
-6.40 |
| P17555 |
SGPPPRPKK |
9.44
|
-0.64 |
-6.68 |
|
PRPKKPSTL |
11.34
|
-1.86 |
-7.90 |
| P47068 |
PEPISPETK |
8.88
|
-1.24 |
-7.28 |
|
PSSNPFFRK |
10.48
|
-1.44 |
-7.48 |
|
PHVPSLTNR |
10.58
|
-0.29 |
-6.33 |
| P04050 |
PGSPAYSPK |
11.87
|
-0.80 |
-6.84 |
| P40450 |
SSPKLFPRL |
10.36
|
-1.43 |
-7.47 |
|
HDLVTPPAP |
10.55
|
-0.66 |
-6.70 |
|
PKLFPRLSS |
11.54
|
-0.59 |
-6.63 |
| P40453 |
WKPPDLPIR |
8.48
|
-0.86 |
-6.90 |
|
PDLPIRLRK |
8.64
|
1.13 |
-4.91 |
|
KVPEPPSWK |
12.11
|
0.14 |
-5.90 |
| Q12168 |
RGPPPLPPR |
7.77
|
-3.63 |
-9.67 |
|
DDPYFPQFR |
8.89
|
0.77 |
-5.27 |
|
NDDPYFPQF |
9.26
|
0.04 |
-6.00 |
| P36006 |
MGQPKDPKF |
10.47
|
1.26 |
-4.78 |
|
PMGQPKDPK |
10.88
|
0.32 |
-5.72 |
|
KKPKNPGGL |
11.70
|
-2.77 |
-8.81 |
| P38753 |
NLPIQHPTN |
9.45
|
-3.23 |
-9.27 |
|
NTPVMPPQR |
9.57
|
-1.11 |
-7.15 |
|
PYPSNLPIQ |
11.37
|
-0.12 |
-6.16 |
| P34245 |
AYSTPFGPW |
11.83
|
0.35 |
-5.69 |
|
FGPWPGPAE |
12.33
|
1.97 |
-4.07 |
| Q01389 |
RYPQTPSYY |
9.67
|
-0.85 |
-6.89 |
|
RTEPSTPSR |
10.84
|
0.37 |
-5.67 |
|
SGRRYPQTP |
11.13
|
-1.20 |
-7.24 |
| Q03306 |
PFRIPSSTK |
8.76
|
-1.17 |
-7.21 |
|
SIPRTKPNV |
8.97
|
-1.21 |
-7.25 |
|
NKSIPRTKP |
10.24
|
-2.38 |
-8.42 |
| P34758 |
TGLQPLKPT |
11.18
|
0.42 |
-5.62 |
|
HLPPPPPPR |
11.22
|
-1.41 |
-7.45 |
|
GGLQPLKPT |
11.37
|
0.27 |
-5.77 |
| P53933 |
VAPPPLPNR |
10.59
|
-1.14 |
-7.18 |
|
SYPGNPTSR |
10.82
|
0.04 |
-6.00 |
| Q00453 |
SAPIPLPHQ |
9.31
|
-2.24 |
-8.28 |
|
HQPPPLPIY |
10.27
|
-0.74 |
-6.78 |
|
YFPHPMPSA |
10.71
|
-2.46 |
-8.50 |
| P40021 |
NYVISPNLP |
12.08
|
-1.41 |
-7.45 |
|
ISPNLPTTI |
12.31
|
1.22 |
-4.82 |
|
FLPSTPSQM |
12.33
|
-1.05 |
-7.09 |
| Q12446 |
PQLPNRNNR |
9.58
|
-0.15 |
-6.19 |
|
PFPVPQQQF |
10.26
|
-0.94 |
-6.98 |
|
PVPPPPPMR |
11.83
|
-1.51 |
-7.55 |
| P53735 |
PKLVPPPPR |
10.46
|
-3.46 |
-9.50 |
|
LVPPPPRTR |
10.49
|
-1.98 |
-8.02 |
| P33334 |
PGGPKFEPL |
11.18
|
-0.46 |
-6.50 |
|
GGPKFEPLY |
11.43
|
-0.58 |
-6.62 |
| P40523 |
PGTVPNMQM |
9.02
|
-2.27 |
-8.31 |
|
GGPLASPTH |
12.10
|
-0.45 |
-6.49 |
|
NSPRNPDTG |
12.22
|
1.50 |
-4.54 |
| P40563 |
AGTPNVPTR |
8.12
|
-1.34 |
-7.38 |
|
PSERPKRRA |
11.22
|
0.61 |
-5.43 |
|
RAPPPVPKK |
11.62
|
-2.52 |
-8.56 |
| P53094 |
NVPLPPQTR |
9.49
|
-3.12 |
-9.16 |
|
SAFPQSPIR |
11.38
|
0.14 |
-5.90 |
|
AFPQSPIRA |
11.46
|
-0.02 |
-6.06 |
| P37370 |
PKPRPFQNK |
8.08
|
-2.56 |
-8.60 |
|
KVPQNRPHM |
8.82
|
-1.09 |
-7.13 |
|
QMPKPRPFQ |
9.66
|
0.25 |
-5.79 |
| P39743 |
AYSNPLTSP |
11.83
|
-0.37 |
-6.41 |
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