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Matrix information:
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ADAN-name: MYO5_1ZUY-10.PDB
Scoring matrix: MYO5_1ZUY-10_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.66
Foldx random average score for Saccharomyces cerevisiae: 14.879 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3213509
Proteins after random average filtering: 7178
Total fragments: 1918324
Proteins after disorder filtering: 4820
Total fragments: 130472
Proteins after pattern filtering: 2308
Total fragments: 13675
Proteins after MINT filtering: 44
Total fragments: 847 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
12.66
|
2.09 |
0.00 |
| Best peptides |
YRRIGWMR |
0.00
|
-4.48 |
-6.57 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PGQPPLIN |
12.17
|
-0.33 |
-2.42 |
|
PLLPPLPG |
12.67
|
-0.84 |
-2.93 |
|
PPLPGQPP |
13.93
|
-0.10 |
-2.19 |
| P39113 |
MSPLGAPP |
9.45
|
-2.41 |
-4.50 |
|
THPEGPNC |
10.63
|
-1.56 |
-3.65 |
|
PRRPQKNR |
11.18
|
1.55 |
-0.54 |
| P40073 |
PQQQPSHT |
11.22
|
-0.81 |
-2.90 |
| P25604 |
PKPKSPHL |
9.82
|
0.06 |
-2.03 |
|
HLKPPLPP |
10.79
|
-0.69 |
-2.78 |
|
QDQAPSLP |
11.66
|
-0.62 |
-2.71 |
| P25623 |
PKTVPISI |
11.09
|
-1.39 |
-3.48 |
|
TKPLPVEP |
11.41
|
-1.10 |
-3.19 |
|
TFTPSEVP |
11.73
|
-0.23 |
-2.32 |
| Q05933 |
FRGPAYPS |
9.52
|
-0.28 |
-2.37 |
|
FTLPGTPG |
10.13
|
-0.97 |
-3.06 |
|
PGTPGFPL |
10.97
|
-1.48 |
-3.57 |
| P53094 |
PLKLPPLP |
9.94
|
-2.95 |
-5.04 |
|
AFPQSPIR |
10.10
|
-1.39 |
-3.48 |
|
LKLPPLPL |
11.13
|
-0.39 |
-2.48 |
| Q12451 |
PHLLPWLP |
12.06
|
-2.24 |
-4.33 |
|
PKHAPPPV |
12.07
|
-1.57 |
-3.66 |
|
KHAPPPVP |
12.07
|
-2.08 |
-4.17 |
| P15891 |
VKTPSPAP |
11.03
|
0.12 |
-1.97 |
|
DEPEGEPD |
11.39
|
-0.29 |
-2.38 |
|
AAPPPPPR |
11.82
|
-1.22 |
-3.31 |
| P48562 |
QFPRGPMH |
5.34
|
-5.21 |
-7.30 |
|
NIGPAPRP |
8.68
|
-1.85 |
-3.94 |
|
VQPVAPKN |
9.44
|
-1.54 |
-3.63 |
| P40341 |
SRNIPPPP |
11.01
|
-2.19 |
-4.28 |
|
RNIPPPPP |
11.67
|
-3.74 |
-5.83 |
|
NIPPPPPP |
12.44
|
-1.93 |
-4.02 |
| Q08912 |
CYTPSWGP |
11.67
|
0.25 |
-1.84 |
|
DHPKGPPP |
11.89
|
-2.56 |
-4.65 |
|
PKGPPPPP |
12.06
|
-1.52 |
-3.61 |
| P17555 |
PKKPSTLK |
9.88
|
0.40 |
-1.69 |
|
KSGPPPRP |
10.30
|
-2.62 |
-4.71 |
|
PAPPASVF |
10.58
|
-1.15 |
-3.24 |
| Q12342 |
KAPPPPPP |
12.09
|
-1.79 |
-3.88 |
|
LETPSTPS |
12.18
|
0.83 |
-1.26 |
|
AKAPPPPP |
12.20
|
-1.10 |
-3.19 |
| P47068 |
YVPPGIPT |
8.15
|
-2.22 |
-4.31 |
|
YYVPPGIP |
8.46
|
-3.24 |
-5.33 |
|
PAPPAPLA |
9.70
|
-0.71 |
-2.80 |
| P38822 |
PEVPPPRR |
7.97
|
-2.04 |
-4.13 |
|
RGPAPEVP |
12.81
|
-3.17 |
-5.26 |
| P04050 |
VSSPGFSP |
9.39
|
-1.96 |
-4.05 |
|
PTSPGFGV |
9.88
|
-1.23 |
-3.32 |
|
PVPPPPVR |
9.93
|
-1.61 |
-3.70 |
| P40450 |
PKLFPRLS |
10.62
|
-1.20 |
-3.29 |
|
IAAPAPPP |
11.25
|
-0.76 |
-2.85 |
|
QLPPPPPP |
11.31
|
-1.98 |
-4.07 |
| P40453 |
PEIPPPLP |
9.70
|
-1.23 |
-3.32 |
|
LRKRPPPP |
10.37
|
-3.04 |
-5.13 |
|
RKRPPPPP |
10.44
|
-2.74 |
-4.83 |
| Q12168 |
PNRPGGTT |
9.20
|
-1.66 |
-3.75 |
|
NRGPPPLP |
9.98
|
-1.71 |
-3.80 |
|
PLPPRANV |
11.95
|
1.15 |
-0.94 |
| P41832 |
VIPPAPPM |
10.44
|
-1.44 |
-3.53 |
|
GDSPAPPP |
12.24
|
-1.93 |
-4.02 |
|
DGVIPPAP |
12.24
|
-0.20 |
-2.29 |
| P36006 |
PKNPGGLS |
7.26
|
-2.09 |
-4.18 |
|
NIPIPPPP |
11.23
|
-2.02 |
-4.11 |
|
TANIPIPP |
11.87
|
-0.47 |
-2.56 |
| P38753 |
PVMPPQRQ |
11.84
|
-2.49 |
-4.58 |
|
HISPPVPG |
11.86
|
-0.62 |
-2.71 |
|
ANNTPVMP |
11.99
|
-1.54 |
-3.63 |
| P38237 |
NFQIPSKP |
10.23
|
-2.17 |
-4.26 |
|
PFVPPPNV |
10.83
|
-1.82 |
-3.91 |
|
FVPPPNVP |
11.10
|
-1.79 |
-3.88 |
| P34245 |
STPFGPWP |
8.14
|
-1.68 |
-3.77 |
|
GPWPGPAE |
12.92
|
-2.18 |
-4.27 |
|
PWPGPAEC |
13.27
|
0.92 |
-1.17 |
| Q01389 |
PSYPSIFR |
10.11
|
0.46 |
-1.63 |
|
PKPPANTS |
10.65
|
0.20 |
-1.89 |
|
KRSKPLPP |
10.76
|
-3.04 |
-5.13 |
| Q03306 |
PFRIPSST |
10.78
|
-1.60 |
-3.69 |
|
PRTKPNVP |
11.13
|
-3.25 |
-5.34 |
|
PSSPPPIS |
11.64
|
-1.33 |
-3.42 |
| P34758 |
QLPLEPLK |
10.71
|
0.89 |
-1.20 |
|
HLPPPPPP |
10.98
|
-2.28 |
-4.37 |
|
QQQPQHLP |
12.02
|
2.14 |
0.05 |
| P53933 |
RVAPPPLP |
9.89
|
-4.00 |
-6.09 |
|
RRRPPPPP |
10.41
|
-3.57 |
-5.66 |
|
RRPPPPPI |
11.01
|
-3.89 |
-5.98 |
| P32381 |
LTEPPMNP |
11.54
|
-0.23 |
-2.32 |
| Q00453 |
PMPSAPIP |
9.47
|
-1.33 |
-3.42 |
|
LYAPPYFP |
9.56
|
-1.44 |
-3.53 |
|
YFPHPMPS |
11.24
|
-1.47 |
-3.56 |
| P40021 |
PLPPPLFP |
10.25
|
-1.93 |
-4.02 |
|
YVISPNLP |
10.43
|
-2.52 |
-4.61 |
|
PLPPPARS |
10.60
|
-2.54 |
-4.63 |
| P36150 |
IVVNPSSP |
12.88
|
0.25 |
-1.84 |
|
VVNPSSPS |
13.83
|
1.24 |
-0.85 |
| Q12446 |
RRGPAPPP |
9.37
|
-2.81 |
-4.90 |
|
PFPIPEIP |
9.56
|
-3.94 |
-6.03 |
|
VRLPAPPP |
9.81
|
-0.70 |
-2.79 |
| Q01560 |
QEPPAPQE |
8.65
|
-1.03 |
-3.12 |
|
QAPDAPQE |
10.84
|
-0.16 |
-2.25 |
|
PPPPGEHM |
10.97
|
-0.46 |
-2.55 |
| P00950 |
DVPPPPID |
11.75
|
-0.60 |
-2.69 |
|
FDVPPPPI |
12.26
|
-1.62 |
-3.71 |
|
SFDVPPPP |
12.80
|
-1.45 |
-3.54 |
| P53735 |
KLVPPPPR |
9.28
|
-3.19 |
-5.28 |
|
LVPPPPRT |
9.90
|
-2.86 |
-4.95 |
|
PKLVPPPP |
11.83
|
-2.30 |
-4.39 |
| P33334 |
AIPGGPKF |
9.26
|
-2.98 |
-5.07 |
|
NAIPGGPK |
9.91
|
-1.23 |
-3.32 |
|
FFDPSLNP |
10.63
|
-1.22 |
-3.31 |
| P40523 |
GAPPGTVP |
9.46
|
-2.91 |
-5.00 |
|
PLAPPPHG |
9.95
|
-1.38 |
-3.47 |
|
PVPVGVPP |
10.27
|
-2.84 |
-4.93 |
| P40563 |
MVNPGQLP |
7.06
|
-3.38 |
-5.47 |
|
RRAPPPVP |
9.54
|
-4.71 |
-6.80 |
|
PSERPKRR |
10.04
|
-2.68 |
-4.77 |
| Q08989 |
DHPKGPPP |
11.89
|
-2.56 |
-4.65 |
|
PKGPPPPP |
12.06
|
-1.52 |
-3.61 |
|
KGPPPPPP |
12.76
|
-1.89 |
-3.98 |
| P37370 |
SIPLAPLP |
8.89
|
-2.12 |
-4.21 |
|
PALPGHVP |
9.18
|
-1.99 |
-4.08 |
|
PLSPAPAV |
9.24
|
-0.60 |
-2.69 |
| P39743 |
YSNPLTSP |
14.39
|
1.68 |
-0.41 |
| Q03900 |
NTPSGAPK |
11.59
|
0.59 |
-1.50 |
|
PSGAPKLK |
12.57
|
-1.71 |
-3.80 |
|
PNTPSGAP |
12.68
|
0.31 |
-1.78 |
|
