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Matrix information:
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ADAN-name: MYO5_1ZUY-1.PDB
Scoring matrix: MYO5_1ZUY-1_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.84
Foldx random average score for Saccharomyces cerevisiae: 15.840 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3199153
Proteins after random average filtering: 7178
Total fragments: 1454540
Proteins after disorder filtering: 4211
Total fragments: 62737
Proteins after pattern filtering: 2205
Total fragments: 16912
Proteins after MINT filtering: 44
Total fragments: 1127 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
19.84
|
-5.17 |
0.00 |
| Best peptides |
RKSRDRRRRY |
0.00
|
-3.96 |
1.21 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PLLPPLPGQP |
11.19
|
-10.22 |
-5.05 |
|
LLPPLPGQPP |
11.92
|
-8.92 |
-3.75 |
|
PNEPLLPPLP |
13.07
|
-8.81 |
-3.64 |
| P39113 |
GPRRPQKNRY |
8.55
|
-7.97 |
-2.80 |
|
ASHRGPRRPQ |
10.05
|
-7.22 |
-2.05 |
|
RGPRRPQKNR |
10.19
|
-4.93 |
0.24 |
| P40073 |
QFDGYPQQQP |
13.82
|
-6.32 |
-1.15 |
| P25604 |
PKPKSPHLKP |
7.90
|
-7.65 |
-2.48 |
|
LKPPLPPPPP |
8.68
|
-8.22 |
-3.05 |
|
KPPLPPPPPP |
9.63
|
-10.84 |
-5.67 |
| P25623 |
SKTKPLPVEP |
7.29
|
-8.17 |
-3.00 |
|
QPPLQPQSKT |
12.18
|
-6.45 |
-1.28 |
|
TPPLPPHATP |
12.60
|
-6.43 |
-1.26 |
| Q05933 |
TKFRGPAYPS |
9.12
|
-5.98 |
-0.81 |
|
FPVDPNTDRM |
13.78
|
-6.07 |
-0.90 |
|
TLPGTPGFPL |
13.94
|
-7.14 |
-1.97 |
| P53094 |
YPLKLPPLPL |
9.46
|
-8.77 |
-3.60 |
|
PQTREPNEPP |
9.98
|
-9.11 |
-3.94 |
|
VLNVPLPPQT |
10.49
|
-9.75 |
-4.58 |
| Q12451 |
QPHLLPWLPP |
10.51
|
-8.11 |
-2.94 |
|
LLPWLPPTDT |
11.11
|
-6.60 |
-1.43 |
|
PKHAPPPVPN |
12.19
|
-7.61 |
-2.44 |
| P15891 |
RRATPEKKPK |
10.42
|
-5.98 |
-0.81 |
|
IISPKPFSKP |
11.30
|
-7.49 |
-2.32 |
|
RSSAAPPPPP |
11.38
|
-8.43 |
-3.26 |
| P48562 |
NPYRPHHNMI |
8.80
|
-7.70 |
-2.53 |
|
QPQRTAPKPP |
9.03
|
-10.16 |
-4.99 |
|
QTMRQAPKRP |
11.22
|
-6.65 |
-1.48 |
| P40341 |
RNIPPPPPPP |
9.92
|
-8.99 |
-3.82 |
|
IPPPPPPPPP |
10.05
|
-10.38 |
-5.21 |
|
SRNIPPPPPP |
10.53
|
-9.11 |
-3.94 |
| Q08912 |
DHPKGPPPPP |
9.64
|
-8.61 |
-3.44 |
|
PKGPPPPPPP |
9.83
|
-8.67 |
-3.50 |
|
TPSWGPSPMG |
11.40
|
-6.88 |
-1.71 |
| P17555 |
SKSGPPPRPK |
9.47
|
-7.87 |
-2.70 |
|
RPKKPSTLKT |
10.08
|
-5.86 |
-0.69 |
|
PRPKKPSTLK |
10.84
|
-7.31 |
-2.14 |
| Q12342 |
RKAKAPPPPP |
4.54
|
-8.88 |
-3.71 |
|
AKAPPPPPPP |
9.58
|
-9.19 |
-4.02 |
|
APPPPPPPPP |
11.55
|
-9.87 |
-4.70 |
| P47068 |
PLPRAPPVPP |
8.19
|
-10.95 |
-5.78 |
|
DKVPPHPVPS |
10.96
|
-6.81 |
-1.64 |
|
MPNTAPPLPR |
11.41
|
-9.61 |
-4.44 |
| P38822 |
APEVPPPRRS |
12.19
|
-7.99 |
-2.82 |
|
DRGPAPEVPP |
13.07
|
-7.66 |
-2.49 |
|
PAPEVPPPRR |
14.09
|
-8.02 |
-2.85 |
| P04050 |
LPVPPPPVRP |
10.24
|
-11.00 |
-5.83 |
|
CLPVPPPPVR |
11.01
|
-9.14 |
-3.97 |
|
VPPPPVRPSI |
13.34
|
-6.82 |
-1.65 |
| P40450 |
LPQLPPPPPP |
9.74
|
-11.47 |
-6.30 |
|
KLPQLPPPPP |
9.99
|
-10.12 |
-4.95 |
|
QLPPPPPPPP |
10.31
|
-9.89 |
-4.72 |
| P40453 |
IRLRKRPPPP |
5.46
|
-8.48 |
-3.31 |
|
RLRKRPPPPP |
5.62
|
-10.17 |
-5.00 |
|
LRKRPPPPPP |
6.26
|
-10.43 |
-5.26 |
| Q12168 |
NKVQHPVPKP |
10.72
|
-7.59 |
-2.42 |
|
TTNRGPPPLP |
10.86
|
-9.14 |
-3.97 |
|
RGPPPLPPRA |
12.29
|
-5.75 |
-0.58 |
| P41832 |
VLSSQPPPPP |
9.88
|
-10.11 |
-4.94 |
|
PKGETPPPPP |
10.74
|
-8.24 |
-3.07 |
|
PPPPPPMALF |
11.05
|
-10.52 |
-5.35 |
| P36006 |
KKPKNPGGLS |
9.84
|
-6.78 |
-1.61 |
|
IPIPPPPPPM |
10.40
|
-9.13 |
-3.96 |
|
GQPKDPKFEA |
11.63
|
-9.06 |
-3.89 |
| P38753 |
TPVMPPQRQS |
11.51
|
-6.28 |
-1.11 |
|
PYPSNLPIQH |
13.03
|
-7.05 |
-1.88 |
|
SPPVPGPALY |
13.47
|
-5.92 |
-0.75 |
| P38237 |
DLNDPFVPPP |
11.96
|
-7.99 |
-2.82 |
|
DPFVPPPNVP |
12.34
|
-10.37 |
-5.20 |
|
IPSKPENTVN |
13.08
|
-5.22 |
-0.05 |
| P34245 |
TPFGPWPGPA |
14.28
|
-6.78 |
-1.61 |
|
AYSTPFGPWP |
15.06
|
-5.05 |
0.12 |
|
FGPWPGPAEC |
15.38
|
-3.50 |
1.67 |
| Q01389 |
KRSKPLPPQL |
7.53
|
-8.97 |
-3.80 |
|
APKREAPKPP |
9.46
|
-9.34 |
-4.17 |
|
SKPLPPQLLS |
10.94
|
-6.22 |
-1.05 |
| Q03306 |
KPFRIPSSTK |
9.66
|
-8.36 |
-3.19 |
|
RNKSIPRTKP |
9.82
|
-9.25 |
-4.08 |
|
RQPTPSPPLP |
10.67
|
-8.48 |
-3.31 |
| P34758 |
QQPQHLPPPP |
10.91
|
-9.46 |
-4.29 |
|
PQHLPPPPPP |
11.04
|
-10.20 |
-5.03 |
|
HLPPPPPPRA |
11.14
|
-8.88 |
-3.71 |
| P53933 |
VRTRRRPPPP |
5.95
|
-9.16 |
-3.99 |
|
TRRRPPPPPI |
6.86
|
-8.85 |
-3.68 |
|
RTRRRPPPPP |
8.40
|
-8.96 |
-3.79 |
| P32381 |
LLTEPPMNPL |
10.65
|
-9.23 |
-4.06 |
|
ILLTEPPMNP |
11.37
|
-9.49 |
-4.32 |
| Q00453 |
LPHQPPPLPI |
11.15
|
-9.85 |
-4.68 |
|
IPLPHQPPPL |
11.70
|
-7.64 |
-2.47 |
|
PLPHQPPPLP |
11.80
|
-10.18 |
-5.01 |
| P40021 |
TKNTGPPPPL |
10.08
|
-8.19 |
-3.02 |
|
VLNSPPLPPP |
10.81
|
-11.18 |
-6.01 |
|
PPPPLPPPLF |
11.54
|
-9.33 |
-4.16 |
| P36150 |
NPIVVNPSSP |
15.51
|
-7.05 |
-1.88 |
| Q12446 |
TKHKAPPPPP |
6.70
|
-9.32 |
-4.15 |
|
QQNRPLPQLP |
7.14
|
-11.31 |
-6.14 |
|
RNNRPVPPPP |
7.96
|
-8.80 |
-3.63 |
| Q01560 |
YYPPPPPGEH |
11.87
|
-7.20 |
-2.03 |
|
HQPPEPQPYY |
12.17
|
-6.84 |
-1.67 |
|
PQPYYPPPPP |
12.23
|
-9.74 |
-4.57 |
| P00950 |
RRSFDVPPPP |
9.83
|
-7.71 |
-2.54 |
|
RSFDVPPPPI |
12.16
|
-7.86 |
-2.69 |
|
SFDVPPPPID |
15.09
|
-5.29 |
-0.12 |
| P53735 |
PKLVPPPPRT |
10.40
|
-7.96 |
-2.79 |
|
KLVPPPPRTR |
11.03
|
-9.76 |
-4.59 |
|
APKLVPPPPR |
11.61
|
-9.56 |
-4.39 |
| P33334 |
MPTRFPPAVF |
7.78
|
-10.00 |
-4.83 |
|
DLALPPPPPP |
9.89
|
-9.70 |
-4.53 |
|
ALPPPPPPPP |
10.81
|
-9.74 |
-4.57 |
| P40523 |
PLAPPPHGPF |
11.52
|
-7.78 |
-2.61 |
|
VPVGVPPLAP |
12.48
|
-8.70 |
-3.53 |
|
YMHNSPRNPD |
12.70
|
-7.37 |
-2.20 |
| P40563 |
PKRRAPPPVP |
7.22
|
-9.70 |
-4.53 |
|
RRAPPPVPKK |
8.90
|
-6.99 |
-1.82 |
|
KRRAPPPVPK |
10.25
|
-9.05 |
-3.88 |
| Q08989 |
DHPKGPPPPP |
9.64
|
-8.61 |
-3.44 |
|
PKGPPPPPPP |
9.83
|
-8.67 |
-3.50 |
|
HPKGPPPPPP |
11.56
|
-9.87 |
-4.70 |
| P37370 |
PKPRPFQNKT |
7.62
|
-5.53 |
-0.36 |
|
NPTKSPPPPP |
9.49
|
-10.12 |
-4.95 |
|
QMPKPRPFQN |
9.61
|
-7.08 |
-1.91 |
| P39743 |
AYSNPLTSPV |
14.73
|
-5.06 |
0.11 |
| Q03900 |
TPSGAPKLKN |
13.42
|
-7.51 |
-2.34 |
|
HLPNTPSGAP |
14.33
|
-7.20 |
-2.03 |
|
LPNTPSGAPK |
14.42
|
-6.05 |
-0.88 |
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