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Matrix information:
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ADAN-name: MYO5_1YP5-9.PDB
Scoring matrix: MYO5_1YP5-9_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.55
Foldx random average score for Saccharomyces cerevisiae: 10.143 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3213509
Proteins after random average filtering: 7178
Total fragments: 1666089
Proteins after disorder filtering: 4428
Total fragments: 57143
Proteins after pattern filtering: 2076
Total fragments: 8798
Proteins after MINT filtering: 40
Total fragments: 506 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
12.55
|
1.06 |
0.00 |
| Best peptides |
KRPRPPRK |
0.00
|
-5.65 |
-6.71 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LPGQPPLI |
5.98
|
-2.50 |
-3.56 |
|
LLPPLPGQ |
7.23
|
-3.79 |
-4.85 |
|
NEPLLPPL |
8.49
|
-5.40 |
-6.46 |
| P39113 |
RGPRRPQK |
5.09
|
-4.71 |
-5.77 |
|
GPRRPQKN |
6.02
|
-2.39 |
-3.45 |
|
APPPPPHK |
7.55
|
-0.60 |
-1.66 |
| P40073 |
PQQQPSHT |
9.63
|
-2.08 |
-3.14 |
|
YPQQQPSH |
9.85
|
-1.60 |
-2.66 |
| P25604 |
KPKSPHLK |
5.60
|
-1.50 |
-2.56 |
|
LPPKPNTQ |
5.70
|
-2.27 |
-3.33 |
|
LPPPPPPQ |
6.79
|
-3.63 |
-4.69 |
| P25623 |
PPLQPQSK |
7.73
|
-1.79 |
-2.85 |
|
TPPLPPHA |
8.18
|
-1.19 |
-2.25 |
|
PKTVPISI |
8.34
|
-3.48 |
-4.54 |
| Q05933 |
FPVDPNTD |
9.13
|
-1.26 |
-2.32 |
|
RGPAYPSN |
9.24
|
-1.07 |
-2.13 |
|
TPGFPLNN |
9.84
|
0.47 |
-0.59 |
| P53094 |
YPLKLPPL |
6.12
|
-4.25 |
-5.31 |
|
KLPPLPLT |
6.32
|
-3.45 |
-4.51 |
|
FPQSPIRA |
6.69
|
-1.27 |
-2.33 |
| Q12451 |
LPWLPPTD |
6.88
|
-3.86 |
-4.92 |
|
QPHLLPWL |
7.17
|
-3.60 |
-4.66 |
|
LLPWLPPT |
7.20
|
-3.24 |
-4.30 |
| P15891 |
QPPLPSRN |
5.47
|
-4.60 |
-5.66 |
|
KPEVPEDE |
6.57
|
-1.75 |
-2.81 |
|
APPPPPRR |
7.22
|
-2.38 |
-3.44 |
| P48562 |
KPPISAPR |
6.72
|
-2.08 |
-3.14 |
|
NPYRPHHN |
6.98
|
-1.64 |
-2.70 |
|
VQPVAPKN |
7.08
|
-3.45 |
-4.51 |
| P40341 |
PPPKPPLN |
5.27
|
-4.10 |
-5.16 |
|
PPPPPPPK |
7.72
|
-2.66 |
-3.72 |
|
KPPLNDPS |
8.27
|
-0.33 |
-1.39 |
| Q08912 |
PPPPPDEK |
8.02
|
-2.49 |
-3.55 |
|
PPPPPPPD |
9.32
|
-2.50 |
-3.56 |
|
PPPPPPDE |
9.98
|
-2.76 |
-3.82 |
| P17555 |
RPKKPSTL |
5.70
|
-3.01 |
-4.07 |
|
PRPKKPST |
7.55
|
-3.86 |
-4.92 |
|
GPPPRPKK |
7.98
|
-1.14 |
-2.20 |
| P47068 |
PPHVPSLT |
8.01
|
-2.71 |
-3.77 |
|
VPPVPPVS |
8.09
|
-2.42 |
-3.48 |
|
APPVPPAT |
8.15
|
-1.39 |
-2.45 |
| P38822 |
APEVPPPR |
7.78
|
-3.27 |
-4.33 |
|
PEVPPPRR |
7.88
|
-4.67 |
-5.73 |
| P04050 |
PPVRPSIS |
7.95
|
-3.33 |
-4.39 |
|
LPVPPPPV |
8.13
|
-1.73 |
-2.79 |
|
PPPVRPSI |
8.70
|
-0.75 |
-1.81 |
| P40450 |
PPPLPDLF |
6.57
|
-4.79 |
-5.85 |
|
SPKLFPRL |
7.66
|
-1.63 |
-2.69 |
|
PPPLPESL |
8.12
|
-2.86 |
-3.92 |
| P40453 |
PPPLPPKI |
6.27
|
-4.91 |
-5.97 |
|
PPDLPIRL |
6.70
|
-4.51 |
-5.57 |
|
KVPEPPSW |
6.95
|
-3.51 |
-4.57 |
| Q12168 |
PPPLPPRA |
5.84
|
-5.82 |
-6.88 |
|
VPNRPGGT |
7.80
|
-1.28 |
-2.34 |
|
PVPKPNID |
8.09
|
-3.80 |
-4.86 |
| P41832 |
PPPVPAKL |
6.22
|
-3.57 |
-4.63 |
|
IPPAPPMM |
7.06
|
-2.37 |
-3.43 |
|
PPPPPPMA |
8.01
|
-3.24 |
-4.30 |
| P36006 |
KPKNPGGL |
6.98
|
-0.70 |
-1.76 |
|
GQPKDPKF |
7.43
|
-3.61 |
-4.67 |
|
KKPKNPGG |
7.50
|
-3.70 |
-4.76 |
| P38753 |
TPVMPPQR |
7.54
|
-2.84 |
-3.90 |
|
YPSNLPIQ |
7.56
|
-2.23 |
-3.29 |
|
PVMPPQRQ |
7.88
|
-4.10 |
-5.16 |
| P38237 |
DPFVPPPN |
7.15
|
-2.39 |
-3.45 |
|
PPNVPKKD |
7.47
|
-3.30 |
-4.36 |
|
IPSKPENT |
7.49
|
-0.57 |
-1.63 |
| P34245 |
FGPWPGPA |
7.97
|
-2.66 |
-3.72 |
|
YSTPFGPW |
10.13
|
-2.01 |
-3.07 |
| Q01389 |
KPLPPQLL |
6.26
|
-1.45 |
-2.51 |
|
EAPKPPAN |
7.12
|
-3.32 |
-4.38 |
|
APTKPNPQ |
7.18
|
-2.61 |
-3.67 |
| Q03306 |
KPNVPPLQ |
4.01
|
-3.47 |
-4.53 |
|
KPFRIPSS |
6.44
|
-1.11 |
-2.17 |
|
PFRIPSST |
7.73
|
-3.43 |
-4.49 |
| P34758 |
QLPLEPLK |
6.51
|
-5.27 |
-6.33 |
|
PPPPPPRA |
7.17
|
-3.88 |
-4.94 |
|
LQPLKPTA |
7.41
|
-5.43 |
-6.49 |
| P53933 |
RRPPPPPI |
5.67
|
-5.17 |
-6.23 |
|
PPPLPNRQ |
5.97
|
-6.15 |
-7.21 |
|
PPPIPSTQ |
6.78
|
-3.05 |
-4.11 |
| Q00453 |
LPHQPPPL |
6.75
|
-3.04 |
-4.10 |
|
YFPHPMPS |
7.75
|
-3.90 |
-4.96 |
|
SAPIPLPH |
7.91
|
-3.86 |
-4.92 |
| P40021 |
LPSTPSQM |
7.37
|
-3.21 |
-4.27 |
|
PPPLPPPL |
7.50
|
-4.18 |
-5.24 |
|
PLPPPARS |
7.67
|
-5.15 |
-6.21 |
| Q12446 |
LPQLPNRN |
5.36
|
-4.85 |
-5.91 |
|
IPEIPSTQ |
6.26
|
-2.26 |
-3.32 |
|
LPPLPNQF |
6.37
|
-5.15 |
-6.21 |
| Q01560 |
YPPPPPGE |
8.25
|
-3.72 |
-4.78 |
|
YYPPPPPG |
8.50
|
-5.57 |
-6.63 |
|
QPPEPQPY |
8.57
|
0.14 |
-0.92 |
| P00950 |
FDVPPPPI |
7.68
|
-3.04 |
-4.10 |
|
DVPPPPID |
9.88
|
-2.38 |
-3.44 |
|
VPPPPIDA |
10.06
|
-1.15 |
-2.21 |
| P53735 |
LVPPPPRT |
6.41
|
-4.73 |
-5.79 |
|
KLVPPPPR |
6.71
|
-4.45 |
-5.51 |
|
VPPPPRTR |
9.76
|
-0.79 |
-1.85 |
| P33334 |
MPTRFPPA |
6.47
|
-2.99 |
-4.05 |
|
LPPPPPGF |
7.43
|
-1.85 |
-2.91 |
|
PPPPPGFE |
8.34
|
-2.73 |
-3.79 |
| P40523 |
PVGVPPLA |
7.35
|
-4.83 |
-5.89 |
|
PGTVPNMQ |
8.26
|
-3.82 |
-4.88 |
|
PLPTPVPV |
8.64
|
-3.75 |
-4.81 |
| P40563 |
PSERPKRR |
6.53
|
-4.35 |
-5.41 |
|
RAPPPVPK |
6.64
|
-4.18 |
-5.24 |
|
APPPVPKK |
7.93
|
-1.53 |
-2.59 |
| Q08989 |
PPPPPDEK |
8.02
|
-2.49 |
-3.55 |
|
PPPPPPPD |
9.32
|
-2.50 |
-3.56 |
|
PPPPPPDE |
9.98
|
-2.76 |
-3.82 |
| P37370 |
QMPKPRPF |
5.78
|
-5.27 |
-6.33 |
|
PKPRPFQN |
5.86
|
-5.06 |
-6.12 |
|
RPHMPSVR |
6.13
|
-2.42 |
-3.48 |
| Q03900 |
LPNTPSGA |
8.12
|
-2.70 |
-3.76 |
|
PSGAPKLK |
8.81
|
-2.68 |
-3.74 |
|
