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Matrix information:
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ADAN-name: MYO5_1YP5-7.PDB
Scoring matrix: MYO5_1YP5-7_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.45
Foldx random average score for Saccharomyces cerevisiae: 9.687 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3213509
Proteins after random average filtering: 7178
Total fragments: 1297080
Proteins after disorder filtering: 4488
Total fragments: 57073
Proteins after pattern filtering: 2074
Total fragments: 9636
Proteins after MINT filtering: 41
Total fragments: 637 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAA |
11.45
|
3.43 |
0.00 |
| Best peptides |
FFPFPPWQ |
0.00
|
-2.90 |
-6.33 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PLLPPLPG |
8.19
|
-1.89 |
-5.32 |
|
PGQPPLIN |
9.01
|
-1.62 |
-5.05 |
|
NEPLLPPL |
9.43
|
-1.49 |
-4.92 |
| P39113 |
RGPRRPQK |
6.06
|
-2.23 |
-5.66 |
|
APPPPPHK |
7.13
|
-1.43 |
-4.86 |
|
GPRRPQKN |
7.23
|
-2.24 |
-5.67 |
| P40073 |
YPQQQPSH |
7.86
|
0.77 |
-2.66 |
|
PQQQPSHT |
9.32
|
-0.60 |
-4.03 |
| P25604 |
PLPPKPKS |
7.33
|
-1.32 |
-4.75 |
|
KPKSPHLK |
7.36
|
-1.21 |
-4.64 |
|
PPPPPQPA |
7.67
|
-1.44 |
-4.87 |
| P25623 |
TPPLPPHA |
6.83
|
-1.72 |
-5.15 |
|
KPLPVEPA |
7.47
|
0.07 |
-3.36 |
|
QPPLQPQS |
7.85
|
0.02 |
-3.41 |
| Q05933 |
RGPAYPSN |
8.06
|
0.03 |
-3.40 |
|
TPGFPLNN |
8.12
|
-1.66 |
-5.09 |
|
FRGPAYPS |
8.25
|
0.72 |
-2.71 |
| P53094 |
KLPPLPLT |
6.15
|
-1.22 |
-4.65 |
|
FPQSPIRA |
6.26
|
-1.14 |
-4.57 |
|
YPLKLPPL |
6.59
|
-1.68 |
-5.11 |
| Q12451 |
QPHLLPWL |
4.91
|
-3.31 |
-6.74 |
|
PPPVPNET |
8.49
|
-1.76 |
-5.19 |
|
PKHAPPPV |
8.58
|
-1.24 |
-4.67 |
| P15891 |
QPPLPSRN |
5.57
|
-4.42 |
-7.85 |
|
APPPPPRR |
5.99
|
-3.28 |
-6.71 |
|
PPPPPRRA |
6.31
|
-3.10 |
-6.53 |
| P48562 |
QFPRGPMH |
5.72
|
-1.70 |
-5.13 |
|
KPPISAPR |
6.55
|
-1.25 |
-4.68 |
|
PAPRPPSS |
7.00
|
-1.82 |
-5.25 |
| P40341 |
PPPKPPLN |
6.45
|
-3.40 |
-6.83 |
|
PPPPPPPK |
7.35
|
-2.49 |
-5.92 |
|
KPPLNDPS |
7.69
|
-0.53 |
-3.96 |
| Q08912 |
PPPPPPPD |
7.71
|
-2.16 |
-5.59 |
|
PPPPPDEK |
8.04
|
-1.20 |
-4.63 |
|
PPPPDEKD |
8.36
|
-0.06 |
-3.49 |
| P17555 |
RPKKPSTL |
7.09
|
-1.76 |
-5.19 |
|
PRPKKPST |
7.23
|
-1.01 |
-4.44 |
|
APPPPPPA |
7.37
|
-2.32 |
-5.75 |
| Q12342 |
TPSTPSDG |
9.50
|
-0.88 |
-4.31 |
| P47068 |
VMPFVDPS |
6.18
|
-1.06 |
-4.49 |
|
VPPVPPVS |
6.71
|
-2.69 |
-6.12 |
|
APSPPPHQ |
7.06
|
-1.82 |
-5.25 |
| P38822 |
PEVPPPRR |
7.21
|
-2.91 |
-6.34 |
|
APEVPPPR |
7.48
|
-2.67 |
-6.10 |
| P04050 |
PPVRPSIS |
7.19
|
-2.73 |
-6.16 |
|
PPPVRPSI |
7.94
|
-0.82 |
-4.25 |
|
PVPPPPVR |
8.30
|
-1.98 |
-5.41 |
| P40450 |
PKLFPRLS |
6.81
|
-2.51 |
-5.94 |
|
PPPPPLPQ |
7.31
|
-1.53 |
-4.96 |
|
PPPLPESL |
7.51
|
-1.07 |
-4.50 |
| P40453 |
VPEPPSWK |
4.74
|
-3.85 |
-7.28 |
|
RPPPPPPV |
6.47
|
-1.81 |
-5.24 |
|
KPPDLPIR |
6.59
|
-0.68 |
-4.11 |
| Q12168 |
PPPLPPRA |
5.51
|
-3.46 |
-6.89 |
|
DPYFPQFR |
6.16
|
-2.03 |
-5.46 |
|
VPNRPGGT |
7.25
|
-1.50 |
-4.93 |
| P41832 |
PPPPPPMA |
6.25
|
-2.90 |
-6.33 |
|
PPPVPAKL |
7.33
|
-2.31 |
-5.74 |
|
PPPPPPPM |
7.58
|
-2.26 |
-5.69 |
| P36006 |
PPPPPPMG |
6.41
|
-3.55 |
-6.98 |
|
KKPKNPGG |
6.97
|
-1.09 |
-4.52 |
|
QPKDPKFE |
7.62
|
-0.58 |
-4.01 |
| P38753 |
YPSNLPIQ |
6.38
|
-0.85 |
-4.28 |
|
PVMPPQRQ |
7.36
|
-2.53 |
-5.96 |
|
TPVMPPQR |
7.63
|
-1.92 |
-5.35 |
| P38237 |
PPNVPKKD |
7.59
|
-2.67 |
-6.10 |
|
PFVPPPNV |
8.01
|
-1.59 |
-5.02 |
|
PPPNVPKK |
8.22
|
-0.64 |
-4.07 |
| P34245 |
FGPWPGPA |
6.54
|
-0.98 |
-4.41 |
|
YSTPFGPW |
8.56
|
0.55 |
-2.88 |
| Q01389 |
RSKPLPPQ |
6.79
|
-1.82 |
-5.25 |
|
KPLPPQLL |
6.89
|
-1.32 |
-4.75 |
|
YPQTPSYY |
7.06
|
-3.32 |
-6.75 |
| Q03306 |
KPNVPPLQ |
5.17
|
-2.75 |
-6.18 |
|
KPFRIPSS |
5.64
|
-1.37 |
-4.80 |
|
PFRIPSST |
6.02
|
-2.05 |
-5.48 |
| P34758 |
PPPPPPRA |
5.88
|
-3.34 |
-6.77 |
|
QPNKPNYG |
6.33
|
-2.44 |
-5.87 |
|
VPTQPSYT |
7.03
|
-2.10 |
-5.53 |
| P53933 |
PPPLPNRQ |
5.96
|
-3.16 |
-6.59 |
|
RRPPPPPI |
6.37
|
-1.78 |
-5.21 |
|
PPPIPSTQ |
6.85
|
-1.99 |
-5.42 |
| Q00453 |
FPHPMPSA |
5.49
|
-0.54 |
-3.97 |
|
YFPHPMPS |
5.90
|
-2.92 |
-6.35 |
|
QPPPLPIY |
7.09
|
-0.54 |
-3.97 |
| P40021 |
PLPPPARS |
6.77
|
-2.57 |
-6.00 |
|
PPLFPSSS |
6.89
|
-1.14 |
-4.57 |
|
FLPSTPSQ |
7.36
|
1.10 |
-2.33 |
| Q12446 |
PFPFPVPQ |
5.06
|
-3.64 |
-7.07 |
|
VPPPPPMR |
5.11
|
-3.58 |
-7.01 |
|
PFPFPIPE |
5.97
|
-2.56 |
-5.99 |
| Q01560 |
YYPPPPPG |
5.39
|
-2.51 |
-5.94 |
|
YPPPPPGE |
7.04
|
-1.30 |
-4.73 |
|
QPPEPQPY |
7.90
|
-0.82 |
-4.25 |
| P00950 |
FDVPPPPI |
7.27
|
-1.37 |
-4.80 |
|
VPPPPIDA |
7.53
|
-1.51 |
-4.94 |
|
DVPPPPID |
8.89
|
-0.74 |
-4.17 |
| P53735 |
KLVPPPPR |
5.97
|
-2.51 |
-5.94 |
|
VPPPPRTR |
7.09
|
-2.14 |
-5.57 |
|
PPPPRTRS |
7.68
|
-2.58 |
-6.01 |
| P33334 |
MPTRFPPA |
5.72
|
-3.14 |
-6.57 |
|
PPPPPGFE |
6.97
|
-2.18 |
-5.61 |
|
PPPPPPSN |
7.27
|
-1.99 |
-5.42 |
| P40523 |
VTPQPPSA |
6.75
|
-1.56 |
-4.99 |
|
PLAPPPHG |
7.34
|
-1.86 |
-5.29 |
|
PGTVPNMQ |
7.77
|
-2.68 |
-6.11 |
| P40563 |
PSERPKRR |
6.10
|
-3.13 |
-6.56 |
|
RAPPPVPK |
7.41
|
-1.19 |
-4.62 |
|
VTPKVPER |
7.61
|
-1.14 |
-4.57 |
| Q08989 |
PPPPPPPD |
7.71
|
-2.16 |
-5.59 |
|
PPPPDEKG |
8.01
|
-0.83 |
-4.26 |
|
PPPPPDEK |
8.04
|
-1.20 |
-4.63 |
| P37370 |
MPKPRPFQ |
5.05
|
-4.00 |
-7.43 |
|
APPIPGMG |
5.98
|
-3.61 |
-7.04 |
|
VPSIPSSS |
6.00
|
-2.34 |
-5.77 |
| Q03900 |
HLPNTPSG |
9.23
|
1.81 |
-1.62 |
|
PSGAPKLK |
9.26
|
-1.23 |
-4.66 |
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