ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1YP5-6.PDB
Scoring matrix: MYO5_1YP5-6_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 14.22
Foldx random average score for Saccharomyces cerevisiae: 13.923

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1706179
Proteins after disorder filtering: 4624
 Total fragments: 120037
Proteins after pattern filtering: 2287
 Total fragments: 18269
Proteins after MINT filtering: 44
 Total fragments: 1243

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

14.22

4.08

0.00
Best peptides

DRKIGWRRPR

0.00

-3.31

-7.39
         
Interactors      
P53145

PPLPGQPPLI

9.24

-2.78

-6.86

EPLLPPLPGQ

10.22

-4.23

-8.31

LPPLPGQPPL

10.65

-3.21

-7.29
P39113

ASHRGPRRPQ

5.91

-3.40

-7.48

MSPLGAPPPP

9.63

-1.95

-6.03

THPEGPNCTN

9.93

-0.50

-4.58
P40073

DGYPQQQPSH

12.59

1.97

-2.11

FDGYPQQQPS

13.15

-0.10

-4.18
P25604

HLKPPLPPPP

9.62

-3.07

-7.15

TPPLPPKPKS

10.09

-5.12

-9.20

PKSPHLKPPL

10.12

1.22

-2.86
P25623

TFTPSEVPPS

9.39

-1.02

-5.10

TPPLPPHATP

10.79

-4.23

-8.31

LPVEPASPSI

11.60

-2.73

-6.81
Q05933

TKFRGPAYPS

8.44

-3.09

-7.17

NFTLPGTPGF

10.15

-0.22

-4.30

FRGPAYPSNS

10.47

-1.54

-5.62
P53094

AFPQSPIRAY

9.63

-1.28

-5.36

TREPNEPPPP

10.02

1.57

-2.51

VPLPPQTREP

10.56

-2.02

-6.10
Q12451

LPWLPPTDTR

10.40

-3.50

-7.58

APKHAPPPVP

11.24

-1.37

-5.45

PHLLPWLPPT

11.73

0.11

-3.97
P15891

DEPEGEPDVK

8.12

-1.92

-6.00

APPPPPRRAT

8.84

-4.22

-8.30

RRATPEKKPK

9.47

-3.59

-7.67
P48562

QFPRGPMHPN

7.30

-4.41

-8.49

TMRQAPKRPD

7.53

-3.05

-7.13

NIGPAPRPPS

7.57

-1.74

-5.82
P40341

SRNIPPPPPP

10.13

-3.02

-7.10

NNSRNIPPPP

10.40

2.63

-1.45

PPKPPLNDPS

10.60

-2.13

-6.21
Q08912

DHPKGPPPPP

7.09

-2.40

-6.48

TPSWGPSPMG

8.49

-2.87

-6.95

HPKGPPPPPP

11.36

-1.99

-6.07
P17555

RPKKPSTLKT

9.96

-3.48

-7.56

KSGPPPRPKK

10.29

-2.60

-6.68

PKKPSTLKTK

10.53

-1.22

-5.30
Q12342

RKAKAPPPPP

9.25

-2.98

-7.06

APPPPPPPPP

12.12

-3.32

-7.40

LETPSTPSDG

12.19

0.49

-3.59
P47068

MPNTAPPLPR

9.29

-3.20

-7.28

DPSSNPFFRK

9.35

2.14

-1.94

YYVPPGIPTN

9.46

-3.37

-7.45
P38822

DRGPAPEVPP

8.15

0.54

-3.54

APEVPPPRRS

11.08

-3.24

-7.32

GPAPEVPPPR

12.82

1.15

-2.93
P04050

GYSPGSPAYS

10.12

-1.09

-5.17

SPAYSPKQDE

10.29

-1.22

-5.30

SPNYSPTSPS

10.40

-0.85

-4.93
P40450

DLVTPPAPPL

10.05

-1.90

-5.98

PPLPNGLLSS

10.83

0.64

-3.44

LPQLPPPPPP

10.86

-3.86

-7.94
P40453

SWKPPDLPIR

9.02

-2.96

-7.04

LRKRPPPPPP

9.69

-3.86

-7.94

PPDLPIRLRK

9.91

-2.94

-7.02
Q12168

NRGPPPLPPR

7.72

-3.10

-7.18

TTNRGPPPLP

9.62

-2.60

-6.68

NKVQHPVPKP

10.05

1.76

-2.32
P41832

TPPPPPLPSV

10.23

-3.31

-7.39

DGVIPPAPPM

10.51

-1.42

-5.50

PPLPSVLSSS

10.52

-1.60

-5.68
P36006

PKNPGGLSGK

8.37

-2.10

-6.18

PPPMGQPKDP

9.52

-3.51

-7.59

IPIPPPPPPM

10.47

-3.94

-8.02
P38753

TPVMPPQRQS

8.73

-2.67

-6.75

PPVPGPALYA

9.56

-3.12

-7.20

SPYPSNLPIQ

9.59

-2.21

-6.29
P38237

NFQIPSKPEN

8.13

-2.18

-6.26

DPDLNDPFVP

9.71

2.35

-1.73

DLNDPFVPPP

9.94

-1.45

-5.53
P34245

STPFGPWPGP

9.21

-2.24

-6.32

GPWPGPAECL

9.75

-3.25

-7.33

TPFGPWPGPA

13.19

-1.09

-5.17
Q01389

PKREAPKPPA

9.55

-1.74

-5.82

IPSPSSSPPP

10.03

-1.37

-5.45

SPSYPSIFRR

10.09

-2.26

-6.34
Q03306

NKSIPRTKPN

9.90

-1.70

-5.78

SPPLPQMEFP

10.65

-4.13

-8.21

KPNVPPLQTS

10.76

-3.33

-7.41
P34758

LPPPPPPRAQ

9.84

-3.19

-7.27

LPLEPLKPTA

10.00

-3.03

-7.11

SPSPNPTPSN

10.31

1.72

-2.36
P53933

RPPPPPIPST

9.40

-4.24

-8.32

TRRRPPPPPI

9.98

-2.99

-7.07

RRRPPPPPIP

10.11

-3.21

-7.29
P32381

LLTEPPMNPL

9.92

-4.04

-8.12

ILLTEPPMNP

13.70

0.75

-3.33
Q00453

NLPISTPASP

9.67

-0.17

-4.25

IPLPHQPPPL

9.90

1.13

-2.95

HPMPSAPIPL

9.94

-1.07

-5.15
P40021

NYVISPNLPT

7.63

-0.67

-4.75

TKNTGPPPPL

8.92

-2.97

-7.05

DFLPSTPSQM

9.53

0.66

-3.42
P36150

PIVVNPSSPS

12.97

2.18

-1.90
Q12446

PPRRGPAPPP

7.97

-4.23

-8.31

NRPLPQLPNR

8.45

-1.95

-6.03

TGRRGPAPPP

8.82

-2.84

-6.92
Q01560

PPPPGEHMHG

8.60

-3.25

-7.33

DVPPPSNAPI

10.42

-0.42

-4.50

YYPPPPPGEH

11.13

-3.29

-7.37
P00950

DVPPPPIDAS

10.03

-1.84

-5.92

RRSFDVPPPP

11.46

1.86

-2.22

SFDVPPPPID

12.02

-1.44

-5.52
P53735

KLVPPPPRTR

8.93

-3.63

-7.71

VPPPPRTRSP

10.63

-2.24

-6.32

LVPPPPRTRS

10.92

-3.50

-7.58
P33334

DPSLNPIPHF

7.72

0.69

-3.39

NAIPGGPKFE

8.79

-1.77

-5.85

FFDPSLNPIP

9.08

-1.89

-5.97
P40523

YMHNSPRNPD

9.19

-3.56

-7.64

PPPHGPFSTS

9.74

-2.97

-7.05

GAPPGTVPNM

10.49

-2.25

-6.33
P40563

MVNPGQLPPS

7.59

-3.90

-7.98

RRAPPPVPKK

9.66

-3.62

-7.70

PSERPKRRAP

9.93

-1.68

-5.76
Q08989

DHPKGPPPPP

7.09

-2.40

-6.48

HPKGPPPPPP

11.36

-1.99

-6.07

PPPPPDEKGR

12.02

-2.06

-6.14
P37370

RPHMPSVRPA

7.91

-3.59

-7.67

NPTKSPPPPP

8.20

-2.30

-6.38

PPIPGAVPSV

8.54

-3.47

-7.55
P39743

YSNPLTSPVA

13.56

0.58

-3.50

PAYSNPLTSP

13.72

3.57

-0.51
Q03900

TPSGAPKLKN

10.39

-0.96

-5.04

NTPSGAPKLK

10.86

0.15

-3.93

LPNTPSGAPK

12.05

-2.48

-6.56

 


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