ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1YP5-5.PDB
Scoring matrix: MYO5_1YP5-5_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.73
Foldx random average score for Saccharomyces cerevisiae: 17.924

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1348457
Proteins after disorder filtering: 4519
 Total fragments: 105933
Proteins after pattern filtering: 2291
 Total fragments: 19824
Proteins after MINT filtering: 44
 Total fragments: 1331

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.73

-3.44

0.00
Best peptides

FYNWPRWDHF

0.00

-5.67

-2.23
         
Interactors      
P53145

PLLPPLPGQP

14.34

-8.45

-5.00

PLPGQPPLIN

14.38

-8.06

-4.62

PNEPLLPPLP

14.87

-6.47

-3.02
P39113

GPRRPQKNRY

8.83

-7.12

-3.68

SHRGPRRPQK

9.52

-6.35

-2.90

HRGPRRPQKN

10.01

-6.64

-3.19
P40073

GYPQQQPSHT

11.57

-4.12

-0.68

QFDGYPQQQP

14.23

-5.25

-1.81

FDGYPQQQPS

15.47

-1.79

1.65
P25604

PPLPPKPKSP

10.35

-8.86

-5.41

PHLKPPLPPP

10.49

-8.27

-4.82

PPQDQAPSLP

10.64

-8.08

-4.63
P25623

PPSTPQQSSP

11.50

-6.60

-3.15

PLQPQSKTKP

12.02

-6.66

-3.22

TPPLPPHATP

12.43

-7.78

-4.34
Q05933

FRGPAYPSNS

11.52

-5.57

-2.13

TKFRGPAYPS

14.16

-5.21

-1.77

GPAYPSNSDY

14.25

-3.81

-0.37
P53094

FKSSAFPQSP

8.50

-7.29

-3.85

PPQTREPNEP

10.28

-8.52

-5.07

DPVSPKPVSK

11.77

-6.04

-2.60
Q12451

APKHAPPPVP

9.91

-8.71

-5.27

QPHLLPWLPP

11.01

-7.86

-4.42

PKHAPPPVPN

13.30

-7.54

-4.10
P15891

PPPPPRRATP

8.84

-9.06

-5.62

SRSSAAPPPP

11.39

-7.83

-4.38

PPPPRRATPE

12.26

-6.94

-3.50
P48562

PLNPYRPHHN

8.99

-9.18

-5.73

QPQRTAPKPP

9.17

-9.69

-6.24

PISAPRAPYP

9.86

-5.98

-2.54
P40341

SRNIPPPPPP

9.87

-7.67

-4.22

PPPPPPPPKP

10.27

-9.98

-6.54

NIPPPPPPPP

10.77

-8.61

-5.16
Q08912

HPKGPPPPPP

9.81

-9.42

-5.97

PKGPPPPPPP

10.83

-9.37

-5.92

DHPKGPPPPP

11.05

-7.35

-3.90
P17555

PPPRPKKPST

9.29

-7.23

-3.79

SGPPPRPKKP

11.18

-6.42

-2.98

APPPPPPAPP

11.23

-9.36

-5.91
Q12342

APPPPPPPPP

10.85

-10.29

-6.84

AKAPPPPPPP

11.27

-8.92

-5.47

RKAKAPPPPP

13.56

-6.13

-2.69
P47068

PLPRAPPVPP

9.59

-9.42

-5.97

THSHTAPSPP

9.72

-8.56

-5.12

PPALSAPSIP

10.71

-8.15

-4.71
P38822

APEVPPPRRS

13.62

-7.37

-3.93

DRGPAPEVPP

14.43

-4.02

-0.57

NDRGPAPEVP

14.50

-4.68

-1.23
P04050

PPPPVRPSIS

11.47

-8.34

-4.89

CLPVPPPPVR

12.07

-4.71

-1.27

SPGSPAYSPK

12.58

-6.26

-2.81
P40450

PKLFPRLSSD

9.74

-6.44

-3.00

PPPPPPPPLP

10.64

-9.55

-6.11

PPPPPPPPPP

10.70

-11.11

-7.66
P40453

PPSWKPPDLP

7.99

-9.07

-5.63

TPEIPPPLPP

10.50

-9.06

-5.62

IRLRKRPPPP

10.53

-9.75

-6.30
Q12168

TTNRGPPPLP

10.25

-7.08

-3.64

DNDDPYFPQF

10.75

-5.66

-2.22

PPVPNRPGGT

11.48

-6.57

-3.13
P41832

PPPPPPPPPP

10.70

-11.11

-7.66

APPPPPPPPP

10.85

-10.29

-6.84

SVLSSQPPPP

10.87

-7.69

-4.25
P36006

NIPIPPPPPP

9.93

-8.35

-4.90

PMGQPKDPKF

10.24

-6.17

-2.73

PPPPPPMGQP

11.35

-9.49

-6.04
P38753

SPPVPGPALY

11.60

-6.96

-3.52

YPSNLPIQHP

11.99

-8.11

-4.66

PVMPPQRQSY

12.67

-5.28

-1.84
P38237

DPFVPPPNVP

11.13

-6.33

-2.89

DLNDPFVPPP

11.52

-7.51

-4.06

NFQIPSKPEN

12.32

-5.77

-2.32
P34245

AYSTPFGPWP

10.36

-6.95

-3.51

FGPWPGPAEC

11.32

-6.01

-2.56

STPFGPWPGP

12.86

-7.77

-4.32
Q01389

APKREAPKPP

8.56

-10.82

-7.38

GIGEEAPTKP

10.67

-7.39

-3.94

PSTPSRPVPP

11.59

-7.78

-4.34
Q03306

SIPRTKPNVP

8.66

-8.56

-5.12

SPPLPQMEFP

9.41

-6.57

-3.13

SKASSEPSSP

12.60

-5.84

-2.40
P34758

QPQHLPPPPP

8.78

-9.56

-6.12

GLQPLKPTAT

11.97

-4.57

-1.13

PPPPPRAQQQ

12.07

-7.64

-4.20
P53933

VRTRRRPPPP

9.77

-10.01

-6.56

GYNDLPMELP

10.52

-5.50

-2.06

AKRVAPPPLP

10.60

-5.50

-2.06
P32381

ILLTEPPMNP

16.65

-6.55

-3.11
Q00453

YFPHPMPSAP

6.86

-9.61

-6.16

PLPHQPPPLP

9.77

-8.91

-5.46

PIPLPHQPPP

10.60

-6.71

-3.27
P40021

PPPLPPPLFP

9.96

-7.11

-3.67

PPPPLPPPLF

10.67

-9.19

-5.74

AVLNSPPLPP

12.36

-7.66

-4.21
P36150

NPIVVNPSSP

12.00

-8.11

-4.66

PIVVNPSSPS

15.49

-5.23

-1.79
Q12446

PPPRRGPAPP

9.49

-11.17

-7.72

PNRNNRPVPP

9.82

-7.53

-4.09

PPPPPRASRP

9.90

-8.68

-5.23
Q01560

HHQPPEPQPY

10.41

-7.58

-4.13

EPQPYYPPPP

11.22

-8.56

-5.12

APQESAPQEP

11.40

-8.70

-5.25
P00950

SFDVPPPPID

13.32

-7.36

-3.92

PPPPIDASSP

14.82

-7.18

-3.73

FDVPPPPIDA

15.60

-2.01

1.44
P53735

APKLVPPPPR

12.06

-6.94

-3.50

PKLVPPPPRT

12.20

-6.12

-2.68

VPPPPRTRSP

16.55

-6.20

-2.76
P33334

DFTLPPPPPP

10.18

-7.12

-3.68

DLALPPPPPP

10.44

-6.42

-2.98

TFLPPPPPPP

10.77

-8.26

-4.81
P40523

PVGVPPLAPP

11.25

-8.10

-4.65

PPLAPPPHGP

11.81

-8.69

-5.24

PPHGPFSTSM

12.53

-7.58

-4.13
P40563

PKRRAPPPVP

9.25

-7.21

-3.77

PSERPKRRAP

10.17

-6.43

-2.98

NPGQLPPSLE

12.61

-6.43

-2.98
Q08989

HPKGPPPPPP

9.81

-9.42

-5.97

PKGPPPPPPP

10.83

-9.37

-5.92

DHPKGPPPPP

11.05

-7.35

-3.90
P37370

PKPRPFQNKT

9.31

-7.09

-3.65

HKSPSQPPLP

9.77

-5.54

-2.10

QMPKPRPFQN

10.31

-8.34

-4.89
P39743

PNATIPEDNP

14.71

-3.94

-0.50

PAYSNPLTSP

15.33

-5.87

-2.43
Q03900

TPSGAPKLKN

13.55

-7.12

-3.68

HLPNTPSGAP

13.60

-4.45

-1.01

PSGAPKLKNY

13.80

-5.40

-1.96

 


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