ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1YP5-26.PDB
Scoring matrix: MYO5_1YP5-26_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 12.8
Foldx random average score for Saccharomyces cerevisiae: 10.081

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206331
Proteins after random average filtering: 7178
 Total fragments: 1285706
Proteins after disorder filtering: 4369
 Total fragments: 73688
Proteins after pattern filtering: 2267
 Total fragments: 18198
Proteins after MINT filtering: 43
 Total fragments: 1266

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

12.80

-0.68

0.00
Best peptides

DDRPRMPPW

0.00

-6.86

-6.18
         
Interactors      
P53145

NEPLLPPLP

7.19

-6.20

-5.52

PPLPGQPPL

7.90

-5.53

-4.85

PNEPLLPPL

7.99

-6.29

-5.61
P39113

LGAPPPPPH

4.70

-5.80

-5.12

GAPPPPPHK

5.19

-6.08

-5.40

PRRPQKNRY

5.26

-6.93

-6.25
P40073

GYPQQQPSH

5.41

-6.07

-5.39

DGYPQQQPS

7.75

-4.96

-4.28
P25604

LPPKPKSPH

4.17

-5.47

-4.79

KSPHLKPPL

5.01

-5.36

-4.68

PLPPPPPPQ

5.37

-6.50

-5.82
P25623

DTPPLPPHA

5.27

-6.70

-6.02

SDTPPLPPH

6.04

-5.38

-4.70

SQPPLQPQS

6.61

-7.23

-6.55
Q05933

FTLPGTPGF

7.95

-5.38

-4.70

STFPVDPNT

8.37

-4.95

-4.27

KFRGPAYPS

8.79

-3.31

-2.63
P53094

EPPPPCPAM

4.26

-6.74

-6.06

SAFPQSPIR

6.67

-4.68

-4.00

KLPPLPLTS

7.00

-5.56

-4.88
Q12451

AAPKHAPPP

6.59

-6.09

-5.41

HAPPPVPNE

6.87

-6.70

-6.02

APKHAPPPV

7.64

-3.70

-3.02
P15891

AAPPPPPRR

4.66

-6.50

-5.82

SAAPPPPPR

4.85

-5.75

-5.07

PPPPPRRAT

5.62

-5.62

-4.94
P48562

PLNPYRPHH

4.57

-5.43

-4.75

RQAPKRPDA

6.36

-5.86

-5.18

TAPKPPISA

6.65

-5.03

-4.35
P40341

PPPPPPPPK

4.49

-6.61

-5.93

PPPPPKPPL

4.87

-7.57

-6.89

IPPPPPPPP

5.27

-7.13

-6.45
Q08912

DHPKGPPPP

4.71

-6.18

-5.50

KGPPPPPPP

4.71

-6.40

-5.72

PPPPPPDEK

6.44

-6.32

-5.64
P17555

SGPPPRPKK

3.37

-6.84

-6.16

PPRPKKPST

5.44

-6.36

-5.68

KSGPPPRPK

5.86

-3.98

-3.30
Q12342

KAPPPPPPP

4.75

-7.39

-6.71

PPPPPPPPP

5.44

-7.18

-6.50

APPPPPPPP

5.55

-7.05

-6.37
P47068

HTAPSPPPH

5.31

-5.29

-4.61

SAPPVPPAP

5.55

-6.25

-5.57

SIPPVPPTP

5.58

-6.23

-5.55
P38822

PAPEVPPPR

6.18

-6.05

-5.37

GPAPEVPPP

7.23

-6.54

-5.86

APEVPPPRR

7.72

-4.34

-3.66
P04050

PPPPVRPSI

5.12

-6.43

-5.75

VPPPPVRPS

5.85

-6.04

-5.36

GEAPTSPGF

6.84

-5.28

-4.60
P40450

LPPPPPPPP

5.15

-7.36

-6.68

QLPPPPPPP

5.39

-7.69

-7.01

VPPPPPPPP

5.40

-7.25

-6.57
P40453

EIPPPLPPK

4.36

-8.79

-8.11

RLRKRPPPP

4.71

-8.09

-7.41

RKRPPPPPP

4.75

-8.50

-7.82
Q12168

RGPPPLPPR

4.23

-8.12

-7.44

DDPYFPQFR

6.25

-5.48

-4.80

GPPPLPPRA

6.47

-5.99

-5.31
P41832

PPPPPPPPM

4.47

-6.44

-5.76

PPPPPMALF

4.70

-6.75

-6.07

SQPPPPPPP

4.95

-6.84

-6.16
P36006

PIPPPPPPM

4.68

-6.38

-5.70

SNKKPKNPG

6.01

-4.99

-4.31

IPPPPPPMG

6.09

-6.40

-5.72
P38753

PVMPPQRQS

7.22

-4.72

-4.04

NTPVMPPQR

7.30

-5.99

-5.31

HISPPVPGP

7.73

-5.79

-5.11
P38237

VPPPNVPKK

5.34

-6.53

-5.85

NDPFVPPPN

6.81

-5.52

-4.84

LNDPFVPPP

6.98

-6.74

-6.06
P34245

STPFGPWPG

7.17

-4.31

-3.63

FGPWPGPAE

9.28

-4.63

-3.95

GPWPGPAEC

9.57

-4.65

-3.97
Q01389

SSSPPPIPK

5.75

-4.43

-3.75

PSYPSIFRR

5.77

-6.32

-5.64

SSPPPIPKT

5.82

-6.63

-5.95
Q03306

EEKPFRIPS

4.34

-7.06

-6.38

SPPLPQMEF

4.90

-7.77

-7.09

RTKPNVPPL

5.44

-5.77

-5.09
P34758

HLPPPPPPR

4.15

-7.68

-7.00

HSQPNKPNY

5.16

-7.62

-6.94

LPPPPPPRA

5.71

-6.17

-5.49
P53933

RRRPPPPPI

4.70

-5.70

-5.02

VAPPPLPNR

5.39

-9.10

-8.42

RTRRRPPPP

5.49

-5.52

-4.84
P32381

LTEPPMNPL

7.28

-5.54

-4.86
Q00453

LYAPPYFPH

5.50

-5.08

-4.40

YFPHPMPSA

5.76

-5.61

-4.93

PSAPIPLPH

6.08

-4.61

-3.93
P40021

SPPLPPPAR

4.73

-6.15

-5.47

PPPLPPPLF

5.11

-6.14

-5.46

ESHPPNHPH

5.45

-5.17

-4.49
Q12446

AAPPPPPAF

4.52

-6.10

-5.42

PAPPPPPRR

4.54

-6.57

-5.89

PAPPPPPHR

4.68

-6.53

-5.85
Q01560

PPPPGEHMH

5.73

-5.48

-4.80

YPPPPPGEH

6.03

-5.06

-4.38

EPQPYYPPP

6.32

-6.60

-5.92
P00950

DVPPPPIDA

5.63

-6.55

-5.87

RSFDVPPPP

7.74

-4.51

-3.83

VPPPPIDAS

8.22

-5.41

-4.73
P53735

LVPPPPRTR

4.78

-5.54

-4.86

PAPKLVPPP

5.87

-6.87

-6.19

APKLVPPPP

6.63

-5.61

-4.93
P33334

SKMPTRFPP

3.97

-7.54

-6.86

GLPPPPPGF

4.27

-6.55

-5.87

PPPPPPPGY

4.66

-6.73

-6.05
P40523

VPPLAPPPH

4.64

-5.25

-4.57

LAPPPHGPF

6.43

-5.11

-4.43

GGPLASPTH

6.66

-4.45

-3.77
P40563

RAPPPVPKK

4.60

-6.64

-5.96

RRAPPPVPK

6.39

-4.77

-4.09

EVTPKVPER

6.75

-6.86

-6.18
Q08989

KGPPPPPPP

4.71

-6.40

-5.72

DHPKGPPPP

4.71

-6.18

-5.50

GPPPPPPPP

5.63

-7.02

-6.34
P37370

SQMPKPRPF

3.19

-5.00

-4.32

KVPQNRPHM

4.41

-6.18

-5.50

KSPPPPPSP

4.81

-6.95

-6.27
P39743

SNPLTSPVA

8.11

-4.34

-3.66
Q03900

SHLPNTPSG

8.32

-5.63

-4.95

NTPSGAPKL

9.89

-3.86

-3.18

HLPNTPSGA

9.92

-3.22

-2.54

 


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