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Matrix information:
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ADAN-name: MYO5_1YP5-23.PDB
Scoring matrix: MYO5_1YP5-23_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.92
Foldx random average score for Saccharomyces cerevisiae: 9.243 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3220687
Proteins after random average filtering: 7178
Total fragments: 1514185
Proteins after disorder filtering: 4748
Total fragments: 81740
Proteins after pattern filtering: 2182
Total fragments: 12508
Proteins after MINT filtering: 43
Total fragments: 1012 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
11.92
|
-0.52 |
0.00 |
| Best peptides |
YPRIPWM |
0.00
|
-3.44 |
-2.92 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
EPLLPPL |
6.22
|
-3.24 |
-2.72 |
|
PLLPPLP |
6.33
|
-6.41 |
-5.89 |
|
PPLPGQP |
7.09
|
-4.05 |
-3.53 |
| P39113 |
PRRPQKN |
5.90
|
-1.76 |
-1.24 |
|
GPRRPQK |
6.24
|
-2.49 |
-1.97 |
|
APPPPPH |
6.71
|
-1.76 |
-1.24 |
| P25604 |
PPLPPPP |
6.15
|
-5.81 |
-5.29 |
|
SSPHSIP |
6.15
|
-0.89 |
-0.37 |
|
PPLPPKP |
6.21
|
-4.98 |
-4.46 |
| P25623 |
TPPLPPH |
5.32
|
-1.47 |
-0.95 |
|
KPLPVEP |
6.19
|
-4.09 |
-3.57 |
|
SDTPPLP |
6.82
|
-2.25 |
-1.73 |
| Q05933 |
STFPVDP |
7.37
|
-2.67 |
-2.15 |
|
TFPVDPN |
7.72
|
-1.77 |
-1.25 |
|
FTLPGTP |
8.10
|
-4.76 |
-4.24 |
| P53094 |
LKLPPLP |
5.61
|
-5.30 |
-4.78 |
|
YPLKLPP |
5.64
|
-3.98 |
-3.46 |
|
VPLPPQT |
6.97
|
-3.52 |
-3.00 |
| Q12451 |
PHLLPWL |
4.60
|
-5.36 |
-4.84 |
|
HLLPWLP |
7.03
|
-3.96 |
-3.44 |
|
APKHAPP |
7.30
|
-1.29 |
-0.77 |
| P15891 |
SAAPPPP |
6.82
|
-2.59 |
-2.07 |
|
PPLPSRN |
7.09
|
-4.54 |
-4.02 |
|
PPPPPRR |
7.21
|
-3.32 |
-2.80 |
| P48562 |
APRPPSS |
5.75
|
-2.25 |
-1.73 |
|
FPRGPMH |
5.82
|
-2.34 |
-1.82 |
|
SPLNPYR |
5.95
|
-2.42 |
-1.90 |
| P40341 |
RNIPPPP |
5.90
|
-3.03 |
-2.51 |
|
IPPPPPP |
6.97
|
-2.43 |
-1.91 |
|
PPPPPPP |
7.44
|
-2.45 |
-1.93 |
| Q08912 |
KGPPPPP |
7.16
|
-3.93 |
-3.41 |
|
PPPPPPP |
7.44
|
-2.45 |
-1.93 |
|
TPSWGPS |
7.72
|
-0.63 |
-0.11 |
| P17555 |
PPRPKKP |
4.84
|
-2.62 |
-2.10 |
|
SGPPPRP |
6.23
|
-2.05 |
-1.53 |
|
TAAPAPP |
7.25
|
-1.59 |
-1.07 |
| Q12342 |
KAPPPPP |
7.02
|
-3.75 |
-3.23 |
|
PPPPPPP |
7.44
|
-2.45 |
-1.93 |
|
APPPPPP |
7.46
|
-3.24 |
-2.72 |
| P47068 |
LPRAPPV |
6.55
|
-2.17 |
-1.65 |
|
PPLPRAP |
6.70
|
-4.55 |
-4.03 |
|
SAPPVPP |
6.78
|
-1.75 |
-1.23 |
| P38822 |
APEVPPP |
7.77
|
-2.71 |
-2.19 |
|
PEVPPPR |
8.18
|
-3.35 |
-2.83 |
| P04050 |
TCLPVPP |
6.16
|
-4.08 |
-3.56 |
|
PVRPSIS |
6.17
|
-1.88 |
-1.36 |
|
SPAYSPK |
6.69
|
-0.91 |
-0.39 |
| P40450 |
PPLPESL |
6.24
|
-5.32 |
-4.80 |
|
SPKLFPR |
6.31
|
-3.32 |
-2.80 |
|
PPLPDLF |
6.55
|
-0.74 |
-0.22 |
| P40453 |
RKRPPPP |
3.71
|
-4.12 |
-3.60 |
|
TPEIPPP |
5.64
|
-2.98 |
-2.46 |
|
PEIPPPL |
5.89
|
-2.48 |
-1.96 |
| Q12168 |
PPLPPRA |
6.71
|
-5.29 |
-4.77 |
|
PNRPGGT |
6.80
|
0.66 |
1.18 |
|
RGPPPLP |
6.82
|
-3.68 |
-3.16 |
| P41832 |
TPPPPPL |
5.57
|
-2.08 |
-1.56 |
|
PPAPPMM |
6.38
|
-4.06 |
-3.54 |
|
SPAPPPP |
6.49
|
-2.52 |
-2.00 |
| P36006 |
IPIPPPP |
5.73
|
-2.50 |
-1.98 |
|
PPPPPPM |
6.61
|
-3.21 |
-2.69 |
|
IPPPPPP |
6.97
|
-2.43 |
-1.91 |
| P38753 |
SPPVPGP |
6.56
|
-2.37 |
-1.85 |
|
TPVMPPQ |
7.10
|
-2.43 |
-1.91 |
|
YPSNLPI |
7.98
|
-1.78 |
-1.26 |
| P38237 |
FQIPSKP |
7.02
|
-5.74 |
-5.22 |
|
DPFVPPP |
7.08
|
-2.24 |
-1.72 |
|
PPNVPKK |
8.26
|
-3.61 |
-3.09 |
| P34245 |
TPFGPWP |
7.52
|
-1.59 |
-1.07 |
|
YSTPFGP |
7.89
|
-1.46 |
-0.94 |
|
FGPWPGP |
7.95
|
-1.97 |
-1.45 |
| Q01389 |
PSRPVPP |
5.21
|
-2.58 |
-2.06 |
|
KPLPPQL |
5.24
|
-5.74 |
-5.22 |
|
SSPPPIP |
6.14
|
-2.52 |
-2.00 |
| Q03306 |
PFRIPSS |
5.48
|
-2.42 |
-1.90 |
|
SPPLPQM |
5.53
|
-3.33 |
-2.81 |
|
TPSPPLP |
6.05
|
-3.24 |
-2.72 |
| P34758 |
QHLPPPP |
6.31
|
-4.32 |
-3.80 |
|
LPLEPLK |
6.89
|
-3.23 |
-2.71 |
|
LPPPPPP |
6.96
|
-2.91 |
-2.39 |
| P53933 |
RRRPPPP |
3.65
|
-4.38 |
-3.86 |
|
RRPPPPP |
6.65
|
-3.15 |
-2.63 |
|
RPPPPPI |
6.65
|
-2.99 |
-2.47 |
| P32381 |
TEPPMNP |
7.24
|
-2.38 |
-1.86 |
|
EPPMNPL |
7.91
|
-2.57 |
-2.05 |
| Q00453 |
YFPHPMP |
5.10
|
-2.67 |
-2.15 |
|
SAPIPLP |
5.57
|
-3.46 |
-2.94 |
|
APIPLPH |
5.88
|
-1.63 |
-1.11 |
| P40021 |
PPLPPPL |
5.72
|
-5.59 |
-5.07 |
|
TGPPPPL |
6.04
|
-2.38 |
-1.86 |
|
SPPLPPP |
6.09
|
-3.49 |
-2.97 |
| P36150 |
VVNPSSP |
9.09
|
-1.91 |
-1.39 |
| Q12446 |
NNRPVPP |
5.52
|
-3.17 |
-2.65 |
|
RPLPQLP |
5.61
|
-4.37 |
-3.85 |
|
FPIPEIP |
5.92
|
-5.71 |
-5.19 |
| Q01560 |
YYPPPPP |
6.29
|
-2.31 |
-1.79 |
|
YPPPPPG |
7.01
|
-1.80 |
-1.28 |
|
QPYYPPP |
7.20
|
-1.50 |
-0.98 |
| P00950 |
DVPPPPI |
7.65
|
-1.26 |
-0.74 |
|
VPPPPID |
7.77
|
-2.41 |
-1.89 |
|
FDVPPPP |
7.95
|
-4.05 |
-3.53 |
| P53735 |
PKLVPPP |
6.38
|
-4.04 |
-3.52 |
|
LVPPPPR |
7.54
|
-3.97 |
-3.45 |
|
KLVPPPP |
7.67
|
-4.57 |
-4.05 |
| P33334 |
TFLPPPP |
5.03
|
-4.39 |
-3.87 |
|
SGLPPPP |
5.21
|
-2.98 |
-2.46 |
|
LALPPPP |
6.00
|
-4.94 |
-4.42 |
| P40523 |
SPRNPDT |
5.34
|
-1.31 |
-0.79 |
|
TPLPTPV |
5.82
|
-3.14 |
-2.62 |
|
TPQPPSA |
7.49
|
-1.94 |
-1.42 |
| P40563 |
TPKVPER |
6.33
|
-2.96 |
-2.44 |
|
TPNVPTR |
7.46
|
-2.63 |
-2.11 |
|
SEPPTPA |
7.49
|
-1.10 |
-0.58 |
| Q08989 |
KGPPPPP |
7.16
|
-3.93 |
-3.41 |
|
PPPPPPP |
7.44
|
-2.45 |
-1.93 |
|
GPPPPPP |
7.85
|
-3.22 |
-2.70 |
| P37370 |
QNRPHMP |
4.57
|
-4.56 |
-4.04 |
|
TSIPSPP |
5.56
|
-4.04 |
-3.52 |
|
SSIPLAP |
5.94
|
-1.54 |
-1.02 |
| P39743 |
SNPLTSP |
7.53
|
-3.07 |
-2.55 |
|
TIPEDNP |
8.93
|
-0.60 |
-0.08 |
| Q03900 |
SHLPNTP |
6.64
|
-3.97 |
-3.45 |
|
