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Matrix information:
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ADAN-name: MYO5_1YP5-18.PDB
Scoring matrix: MYO5_1YP5-18_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 15.31
Foldx random average score for Saccharomyces cerevisiae: 15.276 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3199153
Proteins after random average filtering: 7178
Total fragments: 1787643
Proteins after disorder filtering: 4599
Total fragments: 114306
Proteins after pattern filtering: 2257
Total fragments: 17466
Proteins after MINT filtering: 44
Total fragments: 1044 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAAA |
15.31
|
1.80 |
0.00 |
| Best peptides |
RPPIPGRHMW |
0.00
|
-4.97 |
-6.77 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LPPLPGQPPL |
6.18
|
-3.77 |
-5.57 |
|
NEPLLPPLPG |
9.12
|
-1.43 |
-3.23 |
|
LPGQPPLINI |
10.48
|
-1.53 |
-3.33 |
| P39113 |
GPRRPQKNRY |
9.32
|
0.41 |
-1.39 |
|
ASHRGPRRPQ |
9.51
|
-0.02 |
-1.82 |
|
RGPRRPQKNR |
9.85
|
-1.53 |
-3.33 |
| P40073 |
FDGYPQQQPS |
11.53
|
-0.03 |
-1.83 |
| P25604 |
KPKSPHLKPP |
8.96
|
-0.13 |
-1.93 |
|
KPPLPPPPPP |
8.98
|
-3.87 |
-5.67 |
|
LPPPPPPQPA |
9.23
|
-1.58 |
-3.38 |
| P25623 |
LPPHATPKNV |
9.19
|
-2.41 |
-4.21 |
|
QPPLQPQSKT |
9.26
|
-2.00 |
-3.80 |
|
PPLPPHATPK |
11.50
|
-0.50 |
-2.30 |
| Q05933 |
FPVDPNTDRM |
9.34
|
-0.31 |
-2.11 |
|
TKFRGPAYPS |
9.40
|
-0.02 |
-1.82 |
|
NFTLPGTPGF |
11.01
|
-2.10 |
-3.90 |
| P53094 |
YPLKLPPLPL |
6.29
|
-2.71 |
-4.51 |
|
AFPQSPIRAY |
9.54
|
0.12 |
-1.68 |
|
LPPLPLTSDS |
9.71
|
-3.16 |
-4.96 |
| Q12451 |
QPHLLPWLPP |
9.17
|
-1.72 |
-3.52 |
|
LPWLPPTDTR |
10.34
|
-0.19 |
-1.99 |
|
PHLLPWLPPT |
11.52
|
-1.49 |
-3.29 |
| P15891 |
RRATPEKKPK |
6.86
|
-0.26 |
-2.06 |
|
KPEVPEDEPE |
8.76
|
-1.34 |
-3.14 |
|
APPPPPRRAT |
9.53
|
-0.81 |
-2.61 |
| P48562 |
KPPISAPRAP |
7.85
|
-2.23 |
-4.03 |
|
NPYRPHHNMI |
7.86
|
-1.51 |
-3.31 |
|
PPISAPRAPY |
8.68
|
-0.09 |
-1.89 |
| P40341 |
KPPLNDPSNP |
9.81
|
-3.23 |
-5.03 |
|
PPKPPLNDPS |
11.03
|
0.25 |
-1.55 |
|
PPLNDPSNPV |
11.03
|
-0.09 |
-1.89 |
| Q08912 |
TPSWGPSPMG |
10.34
|
-1.36 |
-3.16 |
|
VCYTPSWGPS |
11.43
|
-0.04 |
-1.84 |
|
YTPSWGPSPM |
11.66
|
0.48 |
-1.32 |
| P17555 |
RPKKPSTLKT |
6.70
|
-2.96 |
-4.76 |
|
GPPPRPKKPS |
9.95
|
-0.06 |
-1.86 |
|
SKSGPPPRPK |
10.95
|
0.17 |
-1.63 |
| Q12342 |
RKAKAPPPPP |
11.37
|
-2.42 |
-4.22 |
|
TPSTPSDGGS |
12.09
|
-0.78 |
-2.58 |
|
APPPPPPPPP |
13.68
|
-1.06 |
-2.86 |
| P47068 |
MPNTAPPLPR |
6.38
|
-1.33 |
-3.13 |
|
SRTLPPHVPS |
8.92
|
-1.70 |
-3.50 |
|
DPSSNPFFRK |
9.14
|
0.29 |
-1.51 |
| P38822 |
APEVPPPRRS |
7.98
|
-1.25 |
-3.05 |
|
GPAPEVPPPR |
13.45
|
-0.43 |
-2.23 |
|
VGDTPTTTPG |
14.03
|
0.73 |
-1.07 |
| P04050 |
SPTSPGYSPG |
8.85
|
0.35 |
-1.45 |
|
SPGSPAYSPK |
9.80
|
0.15 |
-1.65 |
|
SPTSPSYSPT |
10.17
|
-0.06 |
-1.86 |
| P40450 |
PPPLPDLFKT |
8.06
|
-0.45 |
-2.25 |
|
SPKLFPRLSS |
8.64
|
-1.07 |
-2.87 |
|
LPQLPPPPPP |
9.48
|
-4.26 |
-6.06 |
| P40453 |
PPDLPIRLRK |
8.00
|
-1.47 |
-3.27 |
|
TPEIPPPLPP |
9.03
|
-2.21 |
-4.01 |
|
MPTTPEIPPP |
10.18
|
-1.90 |
-3.70 |
| Q12168 |
IPPPVPNRPG |
8.66
|
-0.49 |
-2.29 |
|
PPPLPPRANV |
8.97
|
-3.36 |
-5.16 |
|
KVQHPVPKPN |
10.55
|
-0.26 |
-2.06 |
| P41832 |
IPPAPPMMPA |
9.53
|
-1.24 |
-3.04 |
|
PPPLPSVLSS |
9.75
|
-1.69 |
-3.49 |
|
PPPPPPPVPA |
11.02
|
-1.13 |
-2.93 |
| P36006 |
KPKNPGGLSG |
8.84
|
-0.23 |
-2.03 |
|
KSNKKPKNPG |
10.76
|
-0.01 |
-1.81 |
|
GQPKDPKFEA |
11.36
|
0.64 |
-1.16 |
| P38753 |
TPVMPPQRQS |
8.79
|
-1.97 |
-3.77 |
|
YSPYPSNLPI |
9.92
|
0.59 |
-1.21 |
|
NLPIQHPTNS |
11.21
|
-2.71 |
-4.51 |
| P38237 |
VPPPNVPKKD |
11.31
|
-0.01 |
-1.81 |
|
FQIPSKPENT |
11.48
|
-0.14 |
-1.94 |
|
IPSKPENTVN |
11.77
|
0.05 |
-1.75 |
| P34245 |
YSTPFGPWPG |
10.48
|
1.12 |
-0.68 |
|
TPFGPWPGPA |
11.52
|
-0.17 |
-1.97 |
|
FGPWPGPAEC |
12.26
|
1.08 |
-0.72 |
| Q01389 |
SPSYPSIFRR |
7.29
|
-0.07 |
-1.87 |
|
APKREAPKPP |
9.37
|
-0.45 |
-2.25 |
|
SPPASPSYPS |
9.49
|
0.30 |
-1.50 |
| Q03306 |
NKSIPRTKPN |
8.05
|
-0.90 |
-2.70 |
|
GEEKPFRIPS |
10.02
|
-0.38 |
-2.18 |
|
QPTPSPPLPQ |
10.29
|
-0.60 |
-2.40 |
| P34758 |
QLPLEPLKPT |
8.61
|
-2.11 |
-3.91 |
|
LPPPPPPRAQ |
8.93
|
-1.80 |
-3.60 |
|
VPQQLPLEPL |
10.14
|
-0.43 |
-2.23 |
| P53933 |
YNDLPMELPH |
9.68
|
-1.96 |
-3.76 |
|
KRVAPPPLPN |
10.11
|
-0.07 |
-1.87 |
|
RRPPPPPIPS |
10.15
|
-0.70 |
-2.50 |
| P32381 |
LLTEPPMNPL |
11.16
|
-0.26 |
-2.06 |
|
ILLTEPPMNP |
13.18
|
-0.57 |
-2.37 |
| Q00453 |
LPHQPPPLPI |
7.53
|
-1.50 |
-3.30 |
|
PPYFPHPMPS |
8.39
|
-0.75 |
-2.55 |
|
LPISTPASPQ |
9.76
|
-0.91 |
-2.71 |
| P40021 |
LPSTPSQMNY |
7.19
|
-2.62 |
-4.42 |
|
SPPLPPPARS |
8.39
|
-2.06 |
-3.86 |
|
NYVISPNLPT |
8.96
|
-0.63 |
-2.43 |
| P36150 |
PIVVNPSSPS |
12.50
|
-0.39 |
-2.19 |
|
NPIVVNPSSP |
13.91
|
-0.01 |
-1.81 |
| Q12446 |
LPQLPNRNNR |
6.47
|
-4.04 |
-5.84 |
|
SQPQSNPFPF |
8.42
|
0.18 |
-1.62 |
|
LPPLPNQFAP |
8.71
|
-3.27 |
-5.07 |
| Q01560 |
PPPPPGEHMH |
7.77
|
-1.31 |
-3.11 |
|
QPYYPPPPPG |
10.36
|
-1.90 |
-3.70 |
|
EPPQAPDAPQ |
10.39
|
-0.59 |
-2.39 |
| P00950 |
RRSFDVPPPP |
13.29
|
-1.47 |
-3.27 |
|
RSFDVPPPPI |
13.36
|
-0.63 |
-2.43 |
|
DVPPPPIDAS |
14.86
|
1.34 |
-0.46 |
| P53735 |
APKLVPPPPR |
8.78
|
-3.85 |
-5.65 |
|
PPPPRTRSPV |
11.14
|
-0.62 |
-2.42 |
|
LVPPPPRTRS |
11.21
|
-0.80 |
-2.60 |
| P33334 |
LPPPPPPPPG |
10.04
|
-2.88 |
-4.68 |
|
MPTRFPPAVF |
10.23
|
-0.35 |
-2.15 |
|
MSGLPPPPPG |
10.78
|
-2.73 |
-4.53 |
| P40523 |
YMHNSPRNPD |
10.26
|
-0.01 |
-1.81 |
|
PPGTVPNMQM |
10.36
|
0.65 |
-1.15 |
|
APPPHGPFST |
10.95
|
0.37 |
-1.43 |
| P40563 |
EPPTPAGTPN |
9.56
|
-0.59 |
-2.39 |
|
APPPVPKKPS |
9.80
|
-0.34 |
-2.14 |
|
KRRAPPPVPK |
10.34
|
-0.73 |
-2.53 |
| Q08989 |
PPPPPDEKGR |
11.24
|
-0.73 |
-2.53 |
|
PPPPDEKGRG |
11.73
|
-0.68 |
-2.48 |
|
PPPPPPDEKG |
12.18
|
0.24 |
-1.56 |
| P37370 |
RPHMPSVRPA |
4.95
|
-5.06 |
-6.86 |
|
APPIPGAVPS |
7.03
|
-2.13 |
-3.93 |
|
APKVPQNRPH |
7.13
|
-1.75 |
-3.55 |
| P39743 |
AYSNPLTSPV |
12.79
|
1.13 |
-0.67 |
| Q03900 |
LPNTPSGAPK |
7.80
|
-1.47 |
-3.27 |
|
TPSGAPKLKN |
11.91
|
0.75 |
-1.05 |
|
PSGAPKLKNY |
13.94
|
1.06 |
-0.74 |
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