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Matrix information:
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ADAN-name: MYO5_1YP5-17.PDB
Scoring matrix: MYO5_1YP5-17_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.9
Foldx random average score for Saccharomyces cerevisiae: 14.277 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3206331
Proteins after random average filtering: 7178
Total fragments: 1502830
Proteins after disorder filtering: 4550
Total fragments: 69519
Proteins after pattern filtering: 2059
Total fragments: 7751
Proteins after MINT filtering: 40
Total fragments: 404 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
14.90
|
-4.13 |
0.00 |
| Best peptides |
RRFMKGRHR |
0.00
|
-7.24 |
-3.11 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PGQPPLINI |
12.57
|
-4.71 |
-0.58 |
|
PLLPPLPGQ |
13.48
|
-5.07 |
-0.94 |
| P39113 |
FTHPEGPNC |
9.37
|
-4.62 |
-0.49 |
|
GPRRPQKNR |
9.49
|
-5.89 |
-1.76 |
|
PPPPHKDHL |
10.18
|
-6.04 |
-1.91 |
| P40073 |
GYPQQQPSH |
12.60
|
-1.59 |
2.54 |
| P25604 |
PPKPKSPHL |
9.72
|
-6.95 |
-2.82 |
|
KPKSPHLKP |
11.13
|
-6.01 |
-1.88 |
|
LPPKPNTQL |
11.92
|
-7.54 |
-3.41 |
| P25623 |
PVEPASPSI |
11.34
|
-4.04 |
0.09 |
|
LPPHATPKN |
12.24
|
-3.97 |
0.16 |
|
EPASPSISL |
12.26
|
-3.24 |
0.89 |
| Q05933 |
LPGTPGFPL |
10.56
|
-6.22 |
-2.09 |
|
FRGPAYPSN |
10.96
|
-4.48 |
-0.35 |
|
FTLPGTPGF |
11.20
|
-5.68 |
-1.55 |
| Q08989 |
PPPPDEKGR |
12.00
|
-5.41 |
-1.28 |
|
PPPPPDEKG |
12.76
|
-3.92 |
0.21 |
| Q12451 |
PWLPPTDTR |
13.22
|
-2.83 |
1.30 |
|
PPPVPNETD |
13.31
|
-2.52 |
1.61 |
| P15891 |
RRATPEKKP |
9.82
|
-8.00 |
-3.87 |
|
AAQPPLPSR |
11.11
|
-3.52 |
0.61 |
|
KEPVKTPSP |
11.21
|
-5.21 |
-1.08 |
| P48562 |
NPYRPHHNM |
7.68
|
-6.96 |
-2.83 |
|
GQFPRGPMH |
9.64
|
-4.25 |
-0.12 |
|
PLNPYRPHH |
10.34
|
-5.83 |
-1.70 |
| Q08912 |
YTPSWGPSP |
9.61
|
-3.66 |
0.47 |
|
PPPPPDEKD |
11.72
|
-2.59 |
1.54 |
|
PPPPDEKDR |
12.84
|
-4.76 |
-0.63 |
| P17555 |
RPKKPSTLK |
8.98
|
-8.06 |
-3.93 |
|
SGPPPRPKK |
10.91
|
-5.39 |
-1.26 |
|
PPRPKKPST |
12.10
|
-4.78 |
-0.65 |
| Q12342 |
LETPSTPSD |
12.49
|
-1.30 |
2.83 |
| P47068 |
EPISPETKK |
11.17
|
-3.50 |
0.63 |
|
NTAPPLPRA |
11.36
|
-3.00 |
1.13 |
|
TLPPHVPSL |
11.92
|
-3.20 |
0.93 |
| P04050 |
PPVRPSISF |
8.94
|
-5.59 |
-1.46 |
|
PPPPVRPSI |
9.36
|
-6.23 |
-2.10 |
|
SPTSPGYSP |
10.67
|
-3.51 |
0.62 |
| P40450 |
PPLPESLSM |
11.40
|
-4.59 |
-0.46 |
|
PPLPNGLLS |
11.65
|
-3.66 |
0.47 |
|
PPLPDLFKT |
11.85
|
-4.09 |
0.04 |
| P40453 |
WKPPDLPIR |
10.66
|
-4.75 |
-0.62 |
|
PDLPIRLRK |
11.48
|
-4.17 |
-0.04 |
|
VPEPPSWKP |
12.06
|
-6.17 |
-2.04 |
| Q12168 |
QHPVPKPNI |
10.01
|
-6.18 |
-2.05 |
|
VPNRPGGTT |
10.26
|
-5.81 |
-1.68 |
|
PPLPPRANV |
10.90
|
-7.05 |
-2.92 |
| P41832 |
PPPPPMALF |
10.64
|
-7.59 |
-3.46 |
|
PPPPPLPSV |
10.74
|
-5.56 |
-1.43 |
|
PPPPPVPAK |
12.16
|
-6.05 |
-1.92 |
| P36006 |
MGQPKDPKF |
10.01
|
-5.46 |
-1.33 |
|
KPKNPGGLS |
10.60
|
-4.08 |
0.05 |
|
PPPMGQPKD |
11.02
|
-5.55 |
-1.42 |
| P38753 |
SPPVPGPAL |
8.94
|
-6.44 |
-2.31 |
|
NLPIQHPTN |
10.51
|
-2.25 |
1.88 |
|
HISPPVPGP |
13.39
|
-6.17 |
-2.04 |
| P38237 |
VPPPNVPKK |
10.87
|
-5.55 |
-1.42 |
|
IPSKPENTV |
12.79
|
-6.64 |
-2.51 |
|
FVPPPNVPK |
13.19
|
-5.72 |
-1.59 |
| P34245 |
YSTPFGPWP |
9.27
|
-5.34 |
-1.21 |
|
FGPWPGPAE |
12.06
|
-2.61 |
1.52 |
| Q01389 |
RRYPQTPSY |
7.98
|
-6.66 |
-2.53 |
|
RPVPPDSSY |
8.12
|
-9.47 |
-5.34 |
|
RTEPSTPSR |
9.13
|
-2.87 |
1.26 |
| Q03306 |
NKSIPRTKP |
9.15
|
-6.00 |
-1.87 |
|
SIPRTKPNV |
11.50
|
-6.12 |
-1.99 |
|
TPSPPLPQM |
11.77
|
-7.22 |
-3.09 |
| P34758 |
QQLPLEPLK |
11.66
|
-3.80 |
0.33 |
|
NTTVPQQLP |
11.80
|
-3.47 |
0.66 |
|
QPNKPNYGM |
12.07
|
-6.57 |
-2.44 |
| P53933 |
PPPIPSTQK |
11.25
|
-4.83 |
-0.70 |
|
VAPPPLPNR |
11.33
|
-3.98 |
0.15 |
|
PPPPPIPST |
11.91
|
-4.83 |
-0.70 |
| Q00453 |
SAPIPLPHQ |
9.96
|
-2.86 |
1.27 |
|
YAPPYFPHP |
10.77
|
-6.27 |
-2.14 |
|
MPSAPIPLP |
11.69
|
-7.33 |
-3.20 |
| P40021 |
LPSTPSQMN |
11.27
|
-4.12 |
0.01 |
|
PLPPPARSQ |
11.50
|
-3.35 |
0.78 |
|
LPPPLFPSS |
11.58
|
-4.81 |
-0.68 |
| Q12446 |
RPLPQLPNR |
7.34
|
-9.24 |
-5.11 |
|
PPPPPHRHV |
7.95
|
-8.36 |
-4.23 |
|
PPPPPRASR |
8.86
|
-6.06 |
-1.93 |
| Q01560 |
PPPPPGEHM |
6.72
|
-8.13 |
-4.00 |
|
EPQVPQESA |
11.26
|
-3.95 |
0.18 |
|
QPPEPQPYY |
11.36
|
-5.87 |
-1.74 |
| P00950 |
PPPPIDASS |
13.48
|
-3.34 |
0.79 |
|
VPPPPIDAS |
14.18
|
-4.95 |
-0.82 |
| P53735 |
PPPPRTRSP |
10.91
|
-5.05 |
-0.92 |
|
VPPPPRTRS |
11.67
|
-5.32 |
-1.19 |
| P33334 |
NAIPGGPKF |
7.95
|
-4.46 |
-0.33 |
|
PPPPPGYEI |
9.92
|
-6.13 |
-2.00 |
|
NNAIPGGPK |
10.46
|
-2.65 |
1.48 |
| P40523 |
APPPHGPFS |
11.10
|
-3.60 |
0.53 |
|
TPQPPSAST |
12.40
|
-3.99 |
0.14 |
|
LAPPPHGPF |
12.92
|
-5.40 |
-1.27 |
| P40563 |
NSQPQGPSD |
9.63
|
-1.38 |
2.75 |
|
RAPPPVPKK |
9.74
|
-6.83 |
-2.70 |
|
GMVNPGQLP |
11.09
|
-4.90 |
-0.77 |
| P53094 |
FPQSPIRAY |
10.08
|
-6.16 |
-2.03 |
|
LKLPPLPLT |
11.29
|
-5.38 |
-1.25 |
|
EPPPPCPAM |
11.82
|
-6.15 |
-2.02 |
| P37370 |
RPSPISPSI |
7.57
|
-7.89 |
-3.76 |
|
KVPQNRPHM |
8.07
|
-7.11 |
-2.98 |
|
RPHMPSVRP |
8.35
|
-8.44 |
-4.31 |
| P39743 |
NATIPEDNP |
11.98
|
-3.24 |
0.89 |
|
AYSNPLTSP |
14.10
|
-4.13 |
0.00 |
| Q03900 |
NTPSGAPKL |
12.61
|
-1.94 |
2.19 |
|
LPNTPSGAP |
12.90
|
-6.25 |
-2.12 |
|
PNTPSGAPK |
14.27
|
-3.64 |
0.49 |
|
