ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1YP5-1.PDB
Scoring matrix: MYO5_1YP5-1_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.73
Foldx random average score for Saccharomyces cerevisiae: 12.560

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1528827
Proteins after disorder filtering: 4272
 Total fragments: 72334
Proteins after pattern filtering: 2250
 Total fragments: 18524
Proteins after MINT filtering: 43
 Total fragments: 1264

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

15.73

-4.97

0.00
Best peptides

VRSRRRRRRY

0.00

-7.39

-2.42
         
Interactors      
P53145

LPPLPGQPPL

8.39

-7.56

-2.59

PLLPPLPGQP

8.71

-10.57

-5.60

LPGQPPLINI

8.84

-10.45

-5.48
P39113

GPRRPQKNRY

4.96

-9.33

-4.36

HRGPRRPQKN

6.62

-8.16

-3.19

PLGAPPPPPH

6.85

-11.05

-6.08
P25604

KPPLPPPPPP

5.60

-11.83

-6.86

SPHLKPPLPP

6.74

-11.34

-6.37

LKPPLPPPPP

7.18

-10.11

-5.14
P25623

QPPLQPQSKT

7.92

-9.07

-4.10

SKTKPLPVEP

8.07

-9.45

-4.48

PPLPPHATPK

9.15

-7.52

-2.55
Q05933

FRGPAYPSNS

8.82

-6.79

-1.82

FPVDPNTDRM

9.34

-7.67

-2.70

TKFRGPAYPS

9.55

-8.14

-3.17
P53094

YPLKLPPLPL

6.39

-10.44

-5.47

FKSSAFPQSP

8.20

-7.12

-2.15

VLNVPLPPQT

8.23

-10.24

-5.27
Q12451

QPHLLPWLPP

6.65

-10.12

-5.15

APKHAPPPVP

7.73

-12.01

-7.04

LPWLPPTDTR

8.59

-8.85

-3.88
P15891

RRATPEKKPK

7.41

-7.51

-2.54

PPPPPRRATP

7.93

-10.07

-5.10

SRSSAAPPPP

8.65

-7.41

-2.44
P48562

QPQRTAPKPP

6.52

-11.35

-6.38

NPYRPHHNMI

6.71

-8.02

-3.05

PPISAPRAPY

7.05

-9.28

-4.31
P40341

NNSRNIPPPP

5.37

-10.65

-5.68

SRNIPPPPPP

6.54

-8.95

-3.98

IPPPPPPPPP

7.09

-10.77

-5.80
Q08912

DHPKGPPPPP

6.17

-10.25

-5.28

HPKGPPPPPP

7.16

-10.94

-5.97

PKGPPPPPPP

7.61

-10.09

-5.12
P17555

PPPRPKKPST

7.13

-8.84

-3.87

APPPPPPAPP

7.60

-10.74

-5.77

SKSGPPPRPK

7.84

-7.33

-2.36
Q12342

RKAKAPPPPP

5.49

-9.98

-5.01

APPPPPPPPP

7.25

-10.78

-5.81

AKAPPPPPPP

7.50

-8.96

-3.99
P47068

PLPRAPPVPP

5.79

-11.31

-6.34

DPSSNPFFRK

7.78

-8.83

-3.86

MPNTAPPLPR

7.82

-10.63

-5.66
P38822

APEVPPPRRS

7.51

-9.21

-4.24

DRGPAPEVPP

9.28

-8.52

-3.55

PAPEVPPPRR

10.02

-8.01

-3.04
P04050

LPVPPPPVRP

6.59

-11.68

-6.71

CLPVPPPPVR

8.23

-9.48

-4.51

PPPVRPSISF

9.38

-7.70

-2.73
P40450

LPQLPPPPPP

5.29

-12.87

-7.90

LPPPPPPPPP

6.73

-11.93

-6.96

KLPQLPPPPP

6.88

-10.41

-5.44
P40453

IRLRKRPPPP

3.68

-10.65

-5.68

LRKRPPPPPP

4.12

-11.83

-6.86

RLRKRPPPPP

4.26

-11.40

-6.43
Q12168

PPPLPPRANV

7.71

-9.02

-4.05

NKVQHPVPKP

7.76

-8.77

-3.80

NRGPPPLPPR

8.41

-9.43

-4.46
P41832

VLSSQPPPPP

6.77

-11.09

-6.12

APPPPPPPPP

7.25

-10.78

-5.81

PPPPPPPPPP

7.51

-11.24

-6.27
P36006

PMGQPKDPKF

6.73

-8.34

-3.37

PPPPPPMGQP

7.49

-11.71

-6.74

IPIPPPPPPM

7.55

-9.50

-4.53
P38753

TPVMPPQRQS

8.09

-8.38

-3.41

NLPIQHPTNS

8.44

-6.80

-1.83

NNTPVMPPQR

8.59

-7.75

-2.78
P38237

DPFVPPPNVP

7.72

-10.92

-5.95

DLNDPFVPPP

8.15

-7.71

-2.74

DPDLNDPFVP

8.42

-10.27

-5.30
P34245

TPFGPWPGPA

10.39

-6.81

-1.84

GPWPGPAECL

12.05

-6.87

-1.90
Q01389

APKREAPKPP

6.09

-11.48

-6.51

KRSKPLPPQL

6.56

-8.69

-3.72

APTKPNPQGH

7.87

-8.32

-3.35
Q03306

RNKSIPRTKP

7.67

-9.60

-4.63

KPFRIPSSTK

7.97

-9.35

-4.38

SPPLPQMEFP

7.99

-8.25

-3.28
P34758

QPQHLPPPPP

7.02

-13.49

-8.52

IHSQPNKPNY

7.35

-7.44

-2.47

HLPPPPPPRA

7.80

-9.05

-4.08
P53933

VRTRRRPPPP

2.44

-10.95

-5.98

TRRRPPPPPI

5.43

-9.86

-4.89

RRRPPPPPIP

6.90

-11.11

-6.14
P32381

LLTEPPMNPL

7.54

-9.66

-4.69

ILLTEPPMNP

7.96

-9.11

-4.14
Q00453

MPSAPIPLPH

6.20

-10.38

-5.41

LPHQPPPLPI

6.92

-11.77

-6.80

PIPLPHQPPP

7.82

-7.90

-2.93
P40021

PPPLPPPLFP

7.44

-10.39

-5.42

SPPLPPPARS

7.51

-9.27

-4.30

VLNSPPLPPP

8.03

-11.16

-6.19
P36150

NPIVVNPSSP

9.86

-8.95

-3.98
Q12446

LPAPPPPPRR

6.46

-10.41

-5.44

VRLPAPPPPP

6.50

-11.28

-6.31

NRPVPPPPPM

6.56

-9.63

-4.66
Q01560

HHQPPEPQPY

7.87

-7.34

-2.37

EPQPYYPPPP

8.50

-9.26

-4.29

QPYYPPPPPG

8.76

-10.22

-5.25
P00950

RRSFDVPPPP

8.05

-8.54

-3.57

RSFDVPPPPI

10.44

-7.69

-2.72

VPPPPIDASS

11.07

-7.73

-2.76
P53735

APKLVPPPPR

6.59

-9.61

-4.64

PKLVPPPPRT

7.74

-9.46

-4.49

VPPPPRTRSP

8.49

-8.16

-3.19
P33334

MPTRFPPAVF

5.71

-12.16

-7.19

DLALPPPPPP

5.72

-8.96

-3.99

ALPPPPPPPP

7.32

-10.37

-5.40
P40523

VPPLAPPPHG

8.40

-9.18

-4.21

VPVGVPPLAP

8.56

-9.27

-4.30

YMHNSPRNPD

8.89

-9.78

-4.81
P40563

PKRRAPPPVP

6.33

-11.15

-6.18

RRAPPPVPKK

7.37

-8.10

-3.13

KRRAPPPVPK

7.47

-9.70

-4.73
Q08989

DHPKGPPPPP

6.17

-10.25

-5.28

HPKGPPPPPP

7.16

-10.94

-5.97

PKGPPPPPPP

7.61

-10.09

-5.12
P37370

NPTKSPPPPP

5.71

-11.24

-6.27

VSQMPKPRPF

6.16

-8.88

-3.91

PKPRPFQNKT

6.23

-7.33

-2.36
P39743

PNATIPEDNP

11.17

-8.14

-3.17
Q03900

TPSGAPKLKN

9.49

-7.87

-2.90

LPNTPSGAPK

10.39

-6.51

-1.54

PSGAPKLKNY

10.57

-6.75

-1.78

 


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