ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1VA7-4.PDB
Scoring matrix: MYO5_1VA7-4_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.04
Foldx random average score for Saccharomyces cerevisiae: 23.515

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1542628
Proteins after disorder filtering: 4505
 Total fragments: 95489
Proteins after pattern filtering: 2278
 Total fragments: 20490
Proteins after MINT filtering: 44
 Total fragments: 1336

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.04

1.65

0.00
Best peptides

FRPRRFRPPH

0.00

-3.29

-4.94
         
Interactors      
P53145

NEPLLPPLPG

17.52

-2.30

-3.95

EPLLPPLPGQ

18.01

-2.49

-4.14

PPLPGQPPLI

18.34

-4.03

-5.68
P39113

HRGPRRPQKN

12.48

-3.74

-5.39

PLGAPPPPPH

13.84

-6.34

-7.99

ASHRGPRRPQ

14.64

-3.16

-4.81
P40073

FDGYPQQQPS

15.97

-1.87

-3.52

DGYPQQQPSH

19.81

0.53

-1.12

QFDGYPQQQP

21.06

0.29

-1.36
P25604

LKPPLPPPPP

12.66

-6.63

-8.28

PLPPKPKSPH

13.36

-5.05

-6.70

PKSPHLKPPL

14.55

-3.01

-4.66
P25623

PPLPPHATPK

16.82

-5.28

-6.93

PLPVEPASPS

17.24

-4.86

-6.51

KTKPLPVEPA

17.53

-2.47

-4.12
Q05933

TKFRGPAYPS

11.73

-3.02

-4.67

FRGPAYPSNS

12.43

-4.51

-6.16

TLPGTPGFPL

17.29

-3.90

-5.55
P53094

FKSSAFPQSP

13.00

-4.72

-6.37

YPLKLPPLPL

13.42

-6.40

-8.05

TREPNEPPPP

14.05

-4.98

-6.63
Q12451

PKHAPPPVPN

11.92

-5.83

-7.48

QPHLLPWLPP

16.99

-3.51

-5.16

AAPKHAPPPV

17.96

-3.19

-4.84
P15891

RRATPEKKPK

10.11

-5.32

-6.97

SRSSAAPPPP

13.30

-4.47

-6.12

VKTPSPAPAA

14.87

-2.18

-3.83
P48562

PPISAPRAPY

13.91

-4.59

-6.24

MRQAPKRPDA

14.16

-3.75

-5.40

NIGPAPRPPS

14.33

-3.44

-5.09
P40341

SRNIPPPPPP

12.48

-4.05

-5.70

PPPPPPPPPK

13.56

-6.98

-8.63

PPPPPPKPPL

13.92

-5.51

-7.16
Q08912

PKGPPPPPPP

11.99

-5.61

-7.26

PPPPPPPDEK

15.58

-6.04

-7.69

KGPPPPPPPD

16.08

-3.05

-4.70
P17555

SKSGPPPRPK

10.52

-5.20

-6.85

PRPKKPSTLK

13.07

-4.20

-5.85

APAPPPPPPA

15.49

-5.86

-7.51
Q12342

RKAKAPPPPP

10.58

-5.02

-6.67

AKAPPPPPPP

12.09

-5.33

-6.98

APPPPPPPPP

16.17

-6.80

-8.45
P47068

DKVPPHPVPS

12.45

-4.32

-5.97

SRTLPPHVPS

14.13

-3.55

-5.20

PLPRAPPVPP

14.32

-5.35

-7.00
P38822

DRGPAPEVPP

13.69

-4.08

-5.73

PAPEVPPPRR

17.70

-4.45

-6.10

APEVPPPRRS

18.33

-4.18

-5.83
P04050

PVPPPPVRPS

16.80

-3.89

-5.54

SPGYSPGSPA

16.84

-3.13

-4.78

SPSYSPTSPA

17.46

-3.38

-5.03
P40450

PPPPPPPPPL

13.75

-6.71

-8.36

PPPPPPPLPQ

15.15

-6.26

-7.91

VPPPPPPPPL

15.17

-6.52

-8.17
P40453

LRKRPPPPPP

9.49

-7.72

-9.37

RKRPPPPPPV

9.49

-4.57

-6.22

KRPPPPPPVS

13.51

-4.83

-6.48
Q12168

NRGPPPLPPR

9.56

-6.00

-7.65

NKVQHPVPKP

16.17

-3.76

-5.41

PPPVPNRPGG

16.90

-3.64

-5.29
P41832

PKGETPPPPP

12.70

-5.34

-6.99

PPPPPPPPPM

13.35

-6.71

-8.36

PPPPPPPPPV

15.02

-6.17

-7.82
P36006

PKDPKFEAAY

11.92

-3.09

-4.74

NKKPKNPGGL

12.78

-3.46

-5.11

PPMGQPKDPK

14.44

-5.36

-7.01
P38753

PVMPPQRQSY

17.98

-0.89

-2.54

YSPYPSNLPI

18.70

-1.46

-3.11

NTPVMPPQRQ

19.13

-1.86

-3.51
P38237

DLNDPFVPPP

17.12

-4.26

-5.91

FVPPPNVPKK

17.81

-3.01

-4.66

PFVPPPNVPK

18.41

-3.62

-5.27
P34245

PFGPWPGPAE

19.70

-1.91

-3.56

YSTPFGPWPG

19.98

-2.11

-3.76

TPFGPWPGPA

20.56

-4.13

-5.78
Q01389

PKREAPKPPA

11.55

-4.64

-6.29

KREAPKPPAN

12.29

-4.14

-5.79

GRRYPQTPSY

13.80

-2.59

-4.24
Q03306

YRQPTPSPPL

9.23

-5.81

-7.46

PRTKPNVPPL

11.05

-4.81

-6.46

NKSIPRTKPN

13.59

-4.38

-6.03
P34758

QHLPPPPPPR

15.20

-5.17

-6.82

QPQHLPPPPP

15.61

-5.03

-6.68

QLPLEPLKPT

16.56

-3.44

-5.09
P53933

TRRRPPPPPI

6.80

-5.94

-7.59

RRPPPPPIPS

8.60

-5.59

-7.24

VRTRRRPPPP

8.87

-4.70

-6.35
P32381

LLTEPPMNPL

17.91

-5.62

-7.27
Q00453

FPHPMPSAPI

13.96

-5.50

-7.15

YAPPYFPHPM

14.82

-4.39

-6.04

HPMPSAPIPL

16.41

-5.33

-6.98
P40021

TKNTGPPPPL

12.19

-4.38

-6.03

PPPPLPPPLF

16.17

-4.89

-6.54

NSPPLPPPAR

16.56

-3.15

-4.80
P36150

PIVVNPSSPS

17.53

-4.29

-5.94

NPIVVNPSSP

22.02

-1.47

-3.12
Q12446

NRPVPPPPPM

7.84

-5.78

-7.43

RRGPAPPPPP

9.93

-4.84

-6.49

HKAPPPPPPT

10.69

-5.11

-6.76
Q01560

QPYYPPPPPG

12.74

-4.49

-6.14

PQPYYPPPPP

14.77

-4.57

-6.22

YYPPPPPGEH

15.71

-3.30

-4.95
P00950

RSFDVPPPPI

15.11

-3.49

-5.14

DVPPPPIDAS

17.02

-2.08

-3.73

RRSFDVPPPP

18.83

-2.35

-4.00
P53735

PKLVPPPPRT

13.26

-4.70

-6.35

APKLVPPPPR

14.28

-7.19

-8.84

PPPPRTRSPV

17.82

-3.39

-5.04
P33334

SKMPTRFPPA

11.64

-2.57

-4.22

FLPPPPPPPS

13.13

-6.89

-8.54

KMPTRFPPAV

13.69

-3.89

-5.54
P40523

YMHNSPRNPD

14.37

-4.52

-6.17

GVPPLAPPPH

16.07

-3.89

-5.54

PLAPPPHGPF

16.59

-4.75

-6.40
P40563

KRRAPPPVPK

8.30

-6.77

-8.42

RRAPPPVPKK

10.87

-4.45

-6.10

PKRRAPPPVP

14.55

-4.95

-6.60
Q08989

PKGPPPPPPP

11.99

-5.61

-7.26

PPPPPPPDEK

15.58

-6.04

-7.69

HPKGPPPPPP

16.13

-6.73

-8.38
P37370

PKPRPFQNKT

10.45

-2.88

-4.53

EKPPSPPVAA

12.49

-2.88

-4.53

KKATSAPAPP

13.34

-3.50

-5.15
P39743

PAYSNPLTSP

23.46

-0.98

-2.63
Q03900

HLPNTPSGAP

19.06

-3.27

-4.92

TPSGAPKLKN

20.38

-3.31

-4.96

LPNTPSGAPK

21.30

-4.56

-6.21

 


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