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Matrix information:
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ADAN-name: MYO5_1VA7-27.PDB
Scoring matrix: MYO5_1VA7-27_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 11.1
Foldx random average score for Saccharomyces cerevisiae: 11.992 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3206331
Proteins after random average filtering: 7178
Total fragments: 1678941
Proteins after disorder filtering: 4717
Total fragments: 131285
Proteins after pattern filtering: 2254
Total fragments: 15078
Proteins after MINT filtering: 44
Total fragments: 875 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAAA |
11.10
|
-2.58 |
0.00 |
| Best peptides |
RGTHWDPRR |
0.00
|
-2.00 |
0.58 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LPGQPPLIN |
8.83
|
-4.87 |
-2.29 |
|
PLPGQPPLI |
10.32
|
-2.04 |
0.54 |
|
LPPLPGQPP |
11.15
|
-2.81 |
-0.23 |
| P39113 |
RGPRRPQKN |
4.64
|
-4.99 |
-2.41 |
|
LFTHPEGPN |
5.03
|
-3.10 |
-0.52 |
|
ASHRGPRRP |
7.42
|
-2.62 |
-0.04 |
| P40073 |
FDGYPQQQP |
9.86
|
-4.75 |
-2.17 |
|
YPQQQPSHT |
9.95
|
-3.10 |
-0.52 |
| P25604 |
KSPHLKPPL |
5.51
|
-3.11 |
-0.53 |
|
KPKSPHLKP |
6.89
|
-5.64 |
-3.06 |
|
QDQAPSLPP |
7.32
|
-3.56 |
-0.98 |
| P25623 |
LPVEPASPS |
6.07
|
-5.52 |
-2.94 |
|
LPPHATPKN |
6.30
|
-3.52 |
-0.94 |
|
FTPSEVPPS |
6.89
|
-2.79 |
-0.21 |
| Q05933 |
RGPAYPSNS |
7.33
|
-4.12 |
-1.54 |
|
TKFRGPAYP |
8.23
|
-1.77 |
0.81 |
|
KFRGPAYPS |
8.26
|
-5.21 |
-2.63 |
| P53094 |
REPNEPPPP |
5.99
|
-3.34 |
-0.76 |
|
EPNEPPPPC |
6.34
|
-3.45 |
-0.87 |
|
QTREPNEPP |
7.12
|
-5.47 |
-2.89 |
| Q12451 |
APKHAPPPV |
7.24
|
-5.37 |
-2.79 |
|
PKHAPPPVP |
8.82
|
-5.14 |
-2.56 |
|
AAPKHAPPP |
10.28
|
-4.67 |
-2.09 |
| P15891 |
RSSAAPPPP |
5.96
|
-2.57 |
0.01 |
|
SSAAPPPPP |
6.31
|
-4.16 |
-1.58 |
|
FTPSKSPAP |
7.04
|
-4.68 |
-2.10 |
| P48562 |
QRTAPKPPI |
5.90
|
-5.77 |
-3.19 |
|
IGPAPRPPS |
5.91
|
-7.35 |
-4.77 |
|
MRQAPKRPD |
6.17
|
-4.00 |
-1.42 |
| P40341 |
RNIPPPPPP |
8.23
|
-4.67 |
-2.09 |
|
NSRNIPPPP |
9.06
|
-6.36 |
-3.78 |
|
IPPPPPPPP |
9.82
|
-4.90 |
-2.32 |
| Q08912 |
HGDHPKGPP |
6.40
|
-2.64 |
-0.06 |
|
HPKGPPPPP |
7.02
|
-3.14 |
-0.56 |
|
YTPSWGPSP |
7.34
|
-3.32 |
-0.74 |
| P17555 |
SKSGPPPRP |
6.04
|
-4.53 |
-1.95 |
|
AAPAPPPPP |
7.03
|
-4.51 |
-1.93 |
|
SATAAPAPP |
7.95
|
-1.89 |
0.69 |
| Q12342 |
KAKAPPPPP |
5.91
|
-4.27 |
-1.69 |
|
RKAKAPPPP |
8.09
|
-6.24 |
-3.66 |
|
KAPPPPPPP |
9.87
|
-2.97 |
-0.39 |
| P47068 |
TAPSPPPHQ |
5.71
|
-4.20 |
-1.62 |
|
PNTAPPLPR |
6.43
|
-4.74 |
-2.16 |
|
TPPAPPAPP |
6.54
|
-3.64 |
-1.06 |
| P38822 |
RGPAPEVPP |
6.33
|
-5.46 |
-2.88 |
|
PAPEVPPPR |
7.71
|
-1.70 |
0.88 |
|
APEVPPPRR |
10.00
|
-4.47 |
-1.89 |
| P04050 |
YGEAPTSPG |
7.43
|
-3.56 |
-0.98 |
|
SPTSPSYSP |
7.69
|
-2.45 |
0.13 |
|
SPTSPAYSP |
7.82
|
-2.62 |
-0.04 |
| P40450 |
TPPAPPLPN |
6.30
|
-3.58 |
-1.00 |
|
CIAAPAPPP |
7.20
|
-3.41 |
-0.83 |
|
VSSSPKLFP |
7.56
|
-4.24 |
-1.66 |
| P40453 |
LRKRPPPPP |
4.06
|
-4.78 |
-2.20 |
|
MPTTPEIPP |
5.46
|
-3.96 |
-1.38 |
|
KVPEPPSWK |
5.48
|
-3.76 |
-1.18 |
| Q12168 |
KVQHPVPKP |
5.98
|
-4.38 |
-1.80 |
|
TNRGPPPLP |
7.69
|
-3.52 |
-0.94 |
|
RGPPPLPPR |
8.05
|
-3.99 |
-1.41 |
| P41832 |
KGETPPPPP |
5.73
|
-4.02 |
-1.44 |
|
TGDSPAPPP |
5.94
|
-2.54 |
0.04 |
|
IPPAPPMMP |
6.39
|
-6.21 |
-3.63 |
| P36006 |
KPKNPGGLS |
9.04
|
-4.20 |
-1.62 |
|
SNKKPKNPG |
9.34
|
-1.69 |
0.89 |
|
IPIPPPPPP |
10.04
|
-6.76 |
-4.18 |
| P38753 |
TPVMPPQRQ |
6.79
|
-4.84 |
-2.26 |
|
ANNTPVMPP |
8.49
|
-2.14 |
0.44 |
|
PYPSNLPIQ |
8.80
|
-2.32 |
0.26 |
| P38237 |
QIPSKPENT |
9.05
|
-3.76 |
-1.18 |
|
LNDPFVPPP |
10.15
|
-3.51 |
-0.93 |
|
NDPFVPPPN |
10.83
|
-1.88 |
0.70 |
| P34245 |
TPFGPWPGP |
8.81
|
-3.01 |
-0.43 |
|
YSTPFGPWP |
9.00
|
-5.53 |
-2.95 |
|
AYSTPFGPW |
9.80
|
-1.49 |
1.09 |
| Q01389 |
KREAPKPPA |
5.85
|
-6.55 |
-3.97 |
|
TPSRPVPPD |
5.92
|
-2.14 |
0.44 |
|
SRTEPSTPS |
6.74
|
-2.20 |
0.38 |
| Q03306 |
RQPTPSPPL |
6.25
|
-6.32 |
-3.74 |
|
PTPSPPLPQ |
7.73
|
-4.24 |
-1.66 |
|
SEPSSPPPI |
7.80
|
-1.46 |
1.12 |
| P34758 |
QPQHLPPPP |
6.43
|
-5.34 |
-2.76 |
|
LPLEPLKPT |
6.55
|
-4.74 |
-2.16 |
|
LSSSPSPNP |
6.92
|
-4.43 |
-1.85 |
| P53933 |
RTRRRPPPP |
4.35
|
-3.64 |
-1.06 |
|
TRRRPPPPP |
5.00
|
-6.32 |
-3.74 |
|
KRVAPPPLP |
6.38
|
-6.73 |
-4.15 |
| P32381 |
LLTEPPMNP |
5.46
|
-3.91 |
-1.33 |
|
LTEPPMNPL |
11.27
|
-5.89 |
-3.31 |
| Q00453 |
YFPHPMPSA |
5.94
|
-3.53 |
-0.95 |
|
MPSAPIPLP |
6.52
|
-5.68 |
-3.10 |
|
PLPHQPPPL |
7.00
|
-4.81 |
-2.23 |
| P40021 |
KNTGPPPPL |
5.32
|
-3.56 |
-0.98 |
|
SESHPPNHP |
6.12
|
-2.51 |
0.07 |
|
YVISPNLPT |
6.78
|
-3.25 |
-0.67 |
| P36150 |
IVVNPSSPS |
8.58
|
-3.35 |
-0.77 |
| Q12446 |
RGPAPPPPP |
3.65
|
-8.02 |
-5.44 |
|
RNNRPVPPP |
3.93
|
-3.15 |
-0.57 |
|
RLPAPPPPP |
4.33
|
-7.83 |
-5.25 |
| Q01560 |
QPPEPQPYY |
6.38
|
-4.20 |
-1.62 |
|
APQEPPAPQ |
6.90
|
-0.83 |
1.75 |
|
PPQAPDAPQ |
8.16
|
-2.77 |
-0.19 |
| P00950 |
RSFDVPPPP |
6.87
|
-1.69 |
0.89 |
|
FDVPPPPID |
9.90
|
-5.10 |
-2.52 |
|
SFDVPPPPI |
11.01
|
-2.38 |
0.20 |
| P53735 |
KLVPPPPRT |
9.04
|
-5.86 |
-3.28 |
|
PAPKLVPPP |
11.03
|
-1.56 |
1.02 |
|
PKLVPPPPR |
11.32
|
-5.79 |
-3.21 |
| P33334 |
MPTRFPPAV |
4.95
|
-5.50 |
-2.92 |
|
KMPTRFPPA |
6.75
|
-5.89 |
-3.31 |
|
FDPSLNPIP |
6.85
|
-4.83 |
-2.25 |
| P40523 |
PPLAPPPHG |
6.88
|
-4.82 |
-2.24 |
|
SSVTPQPPS |
7.49
|
-2.35 |
0.23 |
|
MHNSPRNPD |
7.78
|
-2.94 |
-0.36 |
| P40563 |
PSERPKRRA |
6.14
|
-5.00 |
-2.42 |
|
KRRAPPPVP |
7.06
|
-5.95 |
-3.37 |
|
ANSEPPTPA |
8.09
|
-4.10 |
-1.52 |
| Q08989 |
HPKGPPPPP |
7.02
|
-3.14 |
-0.56 |
|
NGDHPKGPP |
7.02
|
-1.58 |
1.00 |
|
KGPPPPPPP |
9.19
|
-5.13 |
-2.55 |
| P37370 |
LPGHVPPPP |
5.80
|
-5.81 |
-3.23 |
|
IPLAPLPPP |
5.95
|
-4.59 |
-2.01 |
|
LPPSAPPPP |
6.08
|
-6.78 |
-4.20 |
| P39743 |
AYSNPLTSP |
11.95
|
-3.89 |
-1.31 |
| Q03900 |
LPNTPSGAP |
8.99
|
-3.41 |
-0.83 |
|
PSGAPKLKN |
9.03
|
-4.08 |
-1.50 |
|
NTPSGAPKL |
9.90
|
-3.17 |
-0.59 |
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