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Matrix information:
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ADAN-name: MYO5_1VA7-2.PDB
Scoring matrix: MYO5_1VA7-2_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.34
Foldx random average score for Saccharomyces cerevisiae: 22.047 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3199153
Proteins after random average filtering: 7178
Total fragments: 1500963
Proteins after disorder filtering: 4525
Total fragments: 97962
Proteins after pattern filtering: 2301
Total fragments: 21393
Proteins after MINT filtering: 44
Total fragments: 1379 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
23.34
|
-2.75 |
0.00 |
| Best peptides |
FKKRMFRERW |
0.00
|
4.26 |
7.01 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PLPGQPPLIN |
17.84
|
-4.36 |
-1.61 |
|
LLPPLPGQPP |
18.89
|
-5.10 |
-2.35 |
|
NEPLLPPLPG |
18.90
|
-2.68 |
0.07 |
| P39113 |
GPRRPQKNRY |
11.63
|
-0.94 |
1.81 |
|
ASHRGPRRPQ |
14.03
|
-3.01 |
-0.26 |
|
PLGAPPPPPH |
14.85
|
-6.65 |
-3.90 |
| P40073 |
FDGYPQQQPS |
16.92
|
0.42 |
3.17 |
|
QFDGYPQQQP |
19.17
|
-0.38 |
2.37 |
|
DGYPQQQPSH |
21.05
|
-0.55 |
2.20 |
| P25604 |
PKPKSPHLKP |
12.49
|
-3.09 |
-0.34 |
|
LKPPLPPPPP |
13.07
|
-7.01 |
-4.26 |
|
PLPPKPKSPH |
14.64
|
-5.89 |
-3.14 |
| P25623 |
SKTKPLPVEP |
15.42
|
-4.36 |
-1.61 |
|
AQTFTPSEVP |
16.88
|
-2.07 |
0.68 |
|
PPLQPQSKTK |
17.45
|
-3.48 |
-0.73 |
| Q05933 |
TKFRGPAYPS |
12.00
|
-3.89 |
-1.14 |
|
FRGPAYPSNS |
13.59
|
-4.21 |
-1.46 |
|
FPVDPNTDRM |
14.91
|
-3.09 |
-0.34 |
| P53094 |
FKSSAFPQSP |
11.32
|
-2.50 |
0.25 |
|
YPLKLPPLPL |
12.12
|
-5.79 |
-3.04 |
|
PQTREPNEPP |
13.03
|
-4.32 |
-1.57 |
| Q12451 |
PKHAPPPVPN |
14.19
|
-6.03 |
-3.28 |
|
QPHLLPWLPP |
15.57
|
-3.78 |
-1.03 |
|
APKHAPPPVP |
16.28
|
-4.25 |
-1.50 |
| P15891 |
PKPEVPEDEP |
13.83
|
-2.35 |
0.40 |
|
SRSSAAPPPP |
14.27
|
-4.79 |
-2.04 |
|
EPVKTPSPAP |
14.87
|
-2.55 |
0.20 |
| P48562 |
QPQRTAPKPP |
12.31
|
-5.59 |
-2.84 |
|
NPYRPHHNMI |
12.66
|
-2.51 |
0.24 |
|
QTMRQAPKRP |
12.75
|
-3.75 |
-1.00 |
| P40341 |
SRNIPPPPPP |
12.85
|
-4.14 |
-1.39 |
|
NIPPPPPPPP |
14.70
|
-5.22 |
-2.47 |
|
PPPPPPPPPK |
15.38
|
-6.90 |
-4.15 |
| Q08912 |
PKGPPPPPPP |
11.91
|
-5.58 |
-2.83 |
|
HPKGPPPPPP |
13.66
|
-6.83 |
-4.08 |
|
DHPKGPPPPP |
14.79
|
-4.43 |
-1.68 |
| P17555 |
SKSGPPPRPK |
12.24
|
-4.44 |
-1.69 |
|
PRPKKPSTLK |
14.37
|
-4.50 |
-1.75 |
|
APPPPPPAPP |
15.87
|
-4.94 |
-2.19 |
| Q12342 |
RKAKAPPPPP |
10.89
|
-4.86 |
-2.11 |
|
AKAPPPPPPP |
11.88
|
-4.96 |
-2.21 |
|
APPPPPPPPP |
15.47
|
-6.77 |
-4.02 |
| P47068 |
PLPRAPPVPP |
11.95
|
-7.44 |
-4.69 |
|
DKVPPHPVPS |
14.73
|
-4.22 |
-1.47 |
|
SRTLPPHVPS |
15.05
|
-2.99 |
-0.24 |
| P38822 |
DRGPAPEVPP |
14.50
|
-4.28 |
-1.53 |
|
APEVPPPRRS |
16.11
|
-4.52 |
-1.77 |
|
PAPEVPPPRR |
16.42
|
-5.06 |
-2.31 |
| P04050 |
SPSYSPTSPA |
15.73
|
-4.05 |
-1.30 |
|
SPTYSPTSPA |
15.78
|
-4.11 |
-1.36 |
|
SPSYSPTSPG |
15.86
|
-3.75 |
-1.00 |
| P40450 |
QLPPPPPPPP |
14.43
|
-6.14 |
-3.39 |
|
PPPPPPPPPP |
15.34
|
-5.88 |
-3.13 |
|
PPPPPPPPPL |
15.88
|
-6.61 |
-3.86 |
| P40453 |
IRLRKRPPPP |
8.82
|
-4.57 |
-1.82 |
|
LRKRPPPPPP |
9.15
|
-7.41 |
-4.66 |
|
TKVPEPPSWK |
13.82
|
-3.73 |
-0.98 |
| Q12168 |
NRGPPPLPPR |
13.51
|
-5.37 |
-2.62 |
|
NKVQHPVPKP |
16.12
|
-3.06 |
-0.31 |
|
DDPYFPQFRS |
17.58
|
0.41 |
3.16 |
| P41832 |
PKGETPPPPP |
12.77
|
-5.70 |
-2.95 |
|
QPPPPPPPPP |
14.37
|
-6.51 |
-3.76 |
|
PPPPPPPPPP |
15.34
|
-5.88 |
-3.13 |
| P36006 |
PKDPKFEAAY |
13.34
|
-4.26 |
-1.51 |
|
NIPIPPPPPP |
14.95
|
-3.99 |
-1.24 |
|
SKSNKKPKNP |
15.49
|
-3.25 |
-0.50 |
| P38753 |
YSPYPSNLPI |
16.35
|
-0.58 |
2.17 |
|
NTPVMPPQRQ |
17.50
|
-1.66 |
1.09 |
|
YPSNLPIQHP |
17.69
|
-2.96 |
-0.21 |
| P38237 |
DLNDPFVPPP |
16.51
|
-5.09 |
-2.34 |
|
DPFVPPPNVP |
16.53
|
-2.36 |
0.39 |
|
QIPSKPENTV |
18.01
|
-0.85 |
1.90 |
| P34245 |
AYSTPFGPWP |
18.64
|
-2.11 |
0.64 |
|
GPWPGPAECL |
19.57
|
-2.76 |
-0.01 |
|
STPFGPWPGP |
19.63
|
-1.52 |
1.23 |
| Q01389 |
APKREAPKPP |
12.98
|
-6.20 |
-3.45 |
|
PKREAPKPPA |
13.44
|
-4.56 |
-1.81 |
|
GRRYPQTPSY |
13.99
|
-2.73 |
0.02 |
| Q03306 |
YRQPTPSPPL |
12.31
|
-5.40 |
-2.65 |
|
PRTKPNVPPL |
13.38
|
-5.28 |
-2.53 |
|
SIPRTKPNVP |
13.63
|
-2.18 |
0.57 |
| P34758 |
HLPPPPPPRA |
13.70
|
-6.68 |
-3.93 |
|
QPQHLPPPPP |
14.88
|
-5.27 |
-2.52 |
|
QHLPPPPPPR |
15.97
|
-4.53 |
-1.78 |
| P53933 |
TRRRPPPPPI |
8.85
|
-5.38 |
-2.63 |
|
VRTRRRPPPP |
10.79
|
-6.08 |
-3.33 |
|
RRRPPPPPIP |
13.96
|
-3.95 |
-1.20 |
| P32381 |
LLTEPPMNPL |
18.00
|
-5.16 |
-2.41 |
|
ILLTEPPMNP |
18.21
|
-5.25 |
-2.50 |
| Q00453 |
APPYFPHPMP |
13.06
|
-4.52 |
-1.77 |
|
FPHPMPSAPI |
13.95
|
-2.97 |
-0.22 |
|
YAPPYFPHPM |
15.08
|
-3.88 |
-1.13 |
| P40021 |
TKNTGPPPPL |
13.69
|
-4.93 |
-2.18 |
|
FLPSTPSQMN |
15.89
|
-2.82 |
-0.07 |
|
SPPLPPPARS |
16.14
|
-5.27 |
-2.52 |
| P36150 |
PIVVNPSSPS |
17.46
|
-3.52 |
-0.77 |
|
NPIVVNPSSP |
19.54
|
-3.19 |
-0.44 |
| Q12446 |
TKHKAPPPPP |
10.28
|
-5.99 |
-3.24 |
|
HKAPPPPPPT |
11.43
|
-6.20 |
-3.45 |
|
NRPVPPPPPM |
12.33
|
-6.03 |
-3.28 |
| Q01560 |
QPYYPPPPPG |
13.24
|
-7.09 |
-4.34 |
|
PQPYYPPPPP |
13.69
|
-3.38 |
-0.63 |
|
EPQPYYPPPP |
15.19
|
-4.69 |
-1.94 |
| P00950 |
SFDVPPPPID |
18.83
|
-2.54 |
0.21 |
|
RSFDVPPPPI |
19.59
|
-2.94 |
-0.19 |
|
DVPPPPIDAS |
19.69
|
-1.80 |
0.95 |
| P53735 |
PKLVPPPPRT |
12.18
|
-5.58 |
-2.83 |
|
APKLVPPPPR |
15.70
|
-6.87 |
-4.12 |
|
LVPPPPRTRS |
17.48
|
-3.04 |
-0.29 |
| P33334 |
MPTRFPPAVF |
10.18
|
-5.49 |
-2.74 |
|
FLPPPPPPPS |
14.70
|
-5.71 |
-2.96 |
|
FTLPPPPPPP |
15.08
|
-4.51 |
-1.76 |
| P40523 |
YMHNSPRNPD |
15.49
|
-3.61 |
-0.86 |
|
PLAPPPHGPF |
15.76
|
-4.68 |
-1.93 |
|
NITPLPTPVP |
16.33
|
-2.06 |
0.69 |
| P40563 |
PKRRAPPPVP |
7.88
|
-5.11 |
-2.36 |
|
PSERPKRRAP |
14.87
|
-2.16 |
0.59 |
|
KRRAPPPVPK |
15.35
|
-6.86 |
-4.11 |
| Q08989 |
PKGPPPPPPP |
11.91
|
-5.58 |
-2.83 |
|
HPKGPPPPPP |
13.66
|
-6.83 |
-4.08 |
|
DHPKGPPPPP |
14.79
|
-4.43 |
-1.68 |
| P37370 |
NRPHMPSVRP |
11.85
|
-2.61 |
0.14 |
|
PKPRPFQNKT |
12.35
|
-2.53 |
0.22 |
|
NPTKSPPPPP |
12.89
|
-6.43 |
-3.68 |
| P39743 |
PNATIPEDNP |
19.77
|
-2.33 |
0.42 |
|
PAYSNPLTSP |
21.37
|
-3.51 |
-0.76 |
| Q03900 |
HLPNTPSGAP |
16.32
|
-5.81 |
-3.06 |
|
TPSGAPKLKN |
20.77
|
-2.61 |
0.14 |
|
LPNTPSGAPK |
20.94
|
-4.13 |
-1.38 |
|
