ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1RUW-4.PDB
Scoring matrix: MYO5_1RUW-4_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.21
Foldx random average score for Saccharomyces cerevisiae: 21.647

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1502678
Proteins after disorder filtering: 4534
 Total fragments: 107926
Proteins after pattern filtering: 2291
 Total fragments: 21298
Proteins after MINT filtering: 44
 Total fragments: 1399


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.21

0.34

0.00
Best peptides

RRPRRFIPAW

0.00

-1.77

-2.11
         
Interactors      
P53145

LLPPLPGQPP

13.30

-4.78

-5.12

LPPLPGQPPL

15.33

-3.79

-4.13

NEPLLPPLPG

16.66

-3.88

-4.22
P39113

PLGAPPPPPH

12.26

-7.45

-7.79

HRGPRRPQKN

12.82

-2.95

-3.29

RGPRRPQKNR

12.82

-1.91

-2.25
P40073

FDGYPQQQPS

16.80

-2.23

-2.57

DGYPQQQPSH

17.01

-0.55

-0.89

QFDGYPQQQP

17.54

-0.09

-0.43
P25604

LKPPLPPPPP

10.01

-5.81

-6.15

PLPPKPKSPH

11.70

-5.86

-6.20

PPPPPPQPAS

12.39

-4.82

-5.16
P25623

PPSTPQQSSP

15.52

-2.36

-2.70

PLPVEPASPS

15.88

-5.77

-6.11

SQPPLQPQSK

16.18

-0.83

-1.17
Q05933

FRGPAYPSNS

12.36

-4.81

-5.15

TKFRGPAYPS

13.93

-2.94

-3.28

TLPGTPGFPL

15.51

-4.22

-4.56
P53094

FKSSAFPQSP

10.57

-3.56

-3.90

AFPQSPIRAY

12.50

-2.72

-3.06

NEPPPPCPAM

13.49

-2.19

-2.53
Q12451

PKHAPPPVPN

14.29

-5.78

-6.12

KHAPPPVPNE

14.46

-0.52

-0.86

QPHLLPWLPP

15.95

-3.40

-3.74
P15891

RRATPEKKPK

11.65

-4.96

-5.30

APPPPPRRAT

12.73

-3.30

-3.64

EPVKTPSPAP

12.82

-2.52

-2.86
P48562

RQAPKRPDAD

10.32

-3.61

-3.95

KPPISAPRAP

12.82

-3.90

-4.24

NIGPAPRPPS

13.09

-4.98

-5.32
P40341

RNIPPPPPPP

11.37

-4.70

-5.04

NIPPPPPPPP

11.77

-5.61

-5.95

SRNIPPPPPP

12.02

-5.83

-6.17
Q08912

PKGPPPPPPP

11.87

-5.44

-5.78

HPKGPPPPPP

12.03

-6.68

-7.02

DHPKGPPPPP

12.62

-4.25

-4.59
P17555

SKSGPPPRPK

12.89

-4.83

-5.17

PAPPPPPPAP

13.21

-4.39

-4.73

PRPKKPSTLK

14.06

-4.95

-5.29
Q12342

RKAKAPPPPP

9.46

-4.74

-5.08

AKAPPPPPPP

11.94

-4.63

-4.97

APPPPPPPPP

13.99

-5.85

-6.19
P47068

PLPRAPPVPP

10.61

-7.11

-7.45

HPVPSAPSAP

12.49

-2.96

-3.30

PPAPPAPPAP

13.70

-4.62

-4.96
P38822

DRGPAPEVPP

13.32

-3.75

-4.09

RGPAPEVPPP

16.33

-1.16

-1.50

PAPEVPPPRR

17.54

-5.04

-5.38
P04050

PPPVRPSISF

14.98

-3.31

-3.65

LPVPPPPVRP

15.51

-4.69

-5.03

PVPPPPVRPS

15.87

-3.67

-4.01
P40450

KLPQLPPPPP

11.19

-6.52

-6.86

QLPPPPPPPP

11.48

-5.70

-6.04

LPPPPPPPPP

12.73

-6.27

-6.61
P40453

LRKRPPPPPP

7.24

-6.17

-6.51

RLRKRPPPPP

9.45

-6.41

-6.75

RKRPPPPPPV

10.60

-4.87

-5.21
Q12168

NRGPPPLPPR

12.56

-5.09

-5.43

NKVQHPVPKP

14.22

-2.80

-3.14

GPPPLPPRAN

14.39

-4.60

-4.94
P41832

PPPPPPVPAK

11.51

-5.85

-6.19

PKGETPPPPP

12.20

-5.40

-5.74

PPPPPPPMAL

12.82

-6.15

-6.49
P36006

PKDPKFEAAY

9.96

-3.25

-3.59

NIPIPPPPPP

11.82

-5.21

-5.55

ANIPIPPPPP

14.02

-3.70

-4.04
P38753

AHISPPVPGP

13.47

-2.89

-3.23

HANNTPVMPP

14.48

-3.21

-3.55

PVMPPQRQSY

16.00

-2.40

-2.74
P38237

DLNDPFVPPP

11.71

-3.68

-4.02

FVPPPNVPKK

16.59

-3.19

-3.53

ENFQIPSKPE

16.75

-0.55

-0.89
P34245

PFGPWPGPAE

16.81

-3.00

-3.34

AYSTPFGPWP

17.49

-0.67

-1.01

YSTPFGPWPG

19.67

-1.94

-2.28
Q01389

PKREAPKPPA

13.27

-4.69

-5.03

SRPVPPDSSY

13.73

-4.00

-4.34

APKREAPKPP

14.29

-5.24

-5.58
Q03306

YRQPTPSPPL

10.67

-5.45

-5.79

MNGRLPNSAP

10.84

-3.23

-3.57

PRTKPNVPPL

12.59

-3.50

-3.84
P34758

QHLPPPPPPR

12.02

-5.64

-5.98

LPPPPPPRAQ

12.18

-6.37

-6.71

HLPPPPPPRA

12.92

-5.91

-6.25
P53933

TRRRPPPPPI

9.22

-5.05

-5.39

VRTRRRPPPP

9.67

-4.90

-5.24

RRPPPPPIPS

9.87

-5.23

-5.57
P32381

LLTEPPMNPL

13.91

-6.77

-7.11
Q00453

PIPLPHQPPP

11.94

-5.01

-5.35

FPHPMPSAPI

13.50

-4.95

-5.29

YFPHPMPSAP

14.22

-3.34

-3.68
P40021

TKNTGPPPPL

13.39

-4.47

-4.81

NSPPLPPPAR

13.68

-4.10

-4.44

LPPPLFPSSS

14.35

-6.48

-6.82
P36150

PIVVNPSSPS

15.08

-4.39

-4.73

NPIVVNPSSP

17.55

-2.11

-2.45
Q12446

RRGPAPPPPP

8.66

-5.42

-5.76

NRNNRPVPPP

10.22

-3.45

-3.79

NRPVPPPPPM

10.26

-5.55

-5.89
Q01560

HQPPEPQPYY

12.42

-1.88

-2.22

HHQPPEPQPY

13.47

-5.23

-5.57

EPQPYYPPPP

13.50

-4.34

-4.68
P00950

DVPPPPIDAS

13.33

-3.41

-3.75

RSFDVPPPPI

14.32

-4.56

-4.90

RRSFDVPPPP

18.23

-3.39

-3.73
P53735

PKLVPPPPRT

14.85

-4.84

-5.18

APKLVPPPPR

15.00

-7.46

-7.80

LVPPPPRTRS

16.20

-3.84

-4.18
P33334

KMPTRFPPAV

9.37

-5.31

-5.65

FLPPPPPPPS

11.66

-7.49

-7.83

ALPPPPPPPP

12.29

-6.15

-6.49
P40523

PLAPPPHGPF

13.09

-5.00

-5.34

YMHNSPRNPD

13.37

-5.45

-5.79

PPHGPFSTSM

15.11

-3.28

-3.62
P40563

KRRAPPPVPK

10.70

-5.96

-6.30

RRAPPPVPKK

10.72

-3.59

-3.93

PKRRAPPPVP

13.13

-2.91

-3.25
Q08989

PKGPPPPPPP

11.87

-5.44

-5.78

HPKGPPPPPP

12.03

-6.68

-7.02

DHPKGPPPPP

12.62

-4.25

-4.59
P37370

EKPPSPPVAA

11.42

-2.98

-3.32

THVSNPPQAP

11.58

-2.22

-2.56

PKPRPFQNKT

11.67

-3.14

-3.48
P39743

PNATIPEDNP

16.81

-1.89

-2.23

PAYSNPLTSP

19.13

-0.92

-1.26
Q03900

HLPNTPSGAP

9.24

-3.33

-3.67

LPNTPSGAPK

18.27

-3.79

-4.13

TPSGAPKLKN

19.74

-3.44

-3.78

 


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