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Matrix information:
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ADAN-name: MYO5_1RUW-16.PDB
Scoring matrix: MYO5_1RUW-16_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.92
Foldx random average score for Saccharomyces cerevisiae: 14.741 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3206331
Proteins after random average filtering: 7178
Total fragments: 1740126
Proteins after disorder filtering: 4674
Total fragments: 104253
Proteins after pattern filtering: 2225
Total fragments: 11596
Proteins after MINT filtering: 44
Total fragments: 630
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
14.92
|
2.09 |
0.00 |
| Best peptides |
YRPLPGRRW |
0.00
|
-3.62 |
-5.71 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
NEPLLPPLP |
9.60
|
-3.27 |
-5.36 |
|
LPPLPGQPP |
11.80
|
-3.07 |
-5.16 |
|
LLPPLPGQP |
11.84
|
-2.99 |
-5.08 |
| P39113 |
ASHRGPRRP |
8.00
|
-1.07 |
-3.16 |
|
MSPLGAPPP |
9.45
|
-3.25 |
-5.34 |
|
RGPRRPQKN |
10.35
|
-2.20 |
-4.29 |
| P40073 |
FDGYPQQQP |
10.56
|
-1.10 |
-3.19 |
|
GYPQQQPSH |
11.66
|
-1.68 |
-3.77 |
| P25604 |
PKPKSPHLK |
10.88
|
-1.03 |
-3.12 |
|
QAPSLPPKP |
10.95
|
-0.77 |
-2.86 |
|
QEQNTPPLP |
12.24
|
-1.74 |
-3.83 |
| P25623 |
SSNLPKTVP |
10.84
|
-1.61 |
-3.70 |
|
PLPVEPASP |
11.01
|
-2.08 |
-4.17 |
|
PSEVPPSTP |
11.71
|
-1.74 |
-3.83 |
| Q05933 |
TKFRGPAYP |
10.66
|
-1.41 |
-3.50 |
|
NFTLPGTPG |
11.31
|
-3.30 |
-5.39 |
|
TFPVDPNTD |
12.51
|
-2.78 |
-4.87 |
| P53094 |
AFPQSPIRA |
10.11
|
-0.92 |
-3.01 |
|
REPNEPPPP |
10.48
|
-3.85 |
-5.94 |
|
NVPLPPQTR |
10.80
|
-3.72 |
-5.81 |
| Q12451 |
PHLLPWLPP |
11.34
|
-2.35 |
-4.44 |
|
AAPKHAPPP |
11.81
|
-1.15 |
-3.24 |
|
LLPWLPPTD |
12.17
|
-2.65 |
-4.74 |
| P15891 |
RRATPEKKP |
6.56
|
-1.22 |
-3.31 |
|
KSFTPSKSP |
9.18
|
-0.91 |
-3.00 |
|
ISPKPFSKP |
9.20
|
-1.22 |
-3.31 |
| P48562 |
PSPLNPYRP |
9.18
|
-1.92 |
-4.01 |
|
QFPRGPMHP |
9.36
|
-2.40 |
-4.49 |
|
TMRQAPKRP |
9.78
|
-1.52 |
-3.61 |
| P40341 |
SRNIPPPPP |
10.33
|
-2.33 |
-4.42 |
|
RNIPPPPPP |
12.66
|
-2.18 |
-4.27 |
|
NDPSNPVSK |
13.70
|
-0.68 |
-2.77 |
| Q08912 |
YTPSWGPSP |
10.46
|
-1.26 |
-3.35 |
|
VCYTPSWGP |
11.24
|
-1.04 |
-3.13 |
|
HGDHPKGPP |
12.50
|
-1.13 |
-3.22 |
| P17555 |
SKSGPPPRP |
11.06
|
-0.77 |
-2.86 |
|
RPKKPSTLK |
13.37
|
-0.89 |
-2.98 |
|
KSGPPPRPK |
13.69
|
-0.08 |
-2.17 |
| Q12342 |
RKAKAPPPP |
8.80
|
-3.10 |
-5.19 |
|
KAKAPPPPP |
12.69
|
-1.62 |
-3.71 |
|
KAPPPPPPP |
13.39
|
-1.83 |
-3.92 |
| P47068 |
YHPMPNTAP |
8.13
|
-2.61 |
-4.70 |
|
SRTLPPHVP |
8.53
|
-2.28 |
-4.37 |
|
KYYVPPGIP |
10.21
|
-2.65 |
-4.74 |
| P38822 |
RGPAPEVPP |
12.39
|
-1.63 |
-3.72 |
|
PEVPPPRRS |
12.68
|
-0.91 |
-3.00 |
|
VGDTPTTTP |
13.48
|
-1.32 |
-3.41 |
| P04050 |
YSPTSPNYS |
11.73
|
0.00 |
-2.09 |
|
YSPTSPSYS |
12.24
|
-1.00 |
-3.09 |
|
GVSSPGFSP |
12.32
|
-1.23 |
-3.32 |
| P40450 |
KLPQLPPPP |
10.44
|
-2.08 |
-4.17 |
|
HDLVTPPAP |
11.06
|
-1.79 |
-3.88 |
|
VSSSPKLFP |
12.51
|
0.64 |
-1.45 |
| P40453 |
RLRKRPPPP |
8.79
|
-2.93 |
-5.02 |
|
LRKRPPPPP |
9.01
|
-2.77 |
-4.86 |
|
RKRPPPPPP |
11.52
|
-1.94 |
-4.03 |
| Q12168 |
KVQHPVPKP |
11.73
|
-2.17 |
-4.26 |
|
VDNDDPYFP |
13.31
|
-0.25 |
-2.34 |
|
NDDPYFPQF |
13.57
|
-0.93 |
-3.02 |
| P41832 |
LSSQPPPPP |
11.36
|
-1.46 |
-3.55 |
|
KGETPPPPP |
11.86
|
-2.57 |
-4.66 |
|
TDGVIPPAP |
12.65
|
-1.25 |
-3.34 |
| P36006 |
KSNKKPKNP |
10.23
|
-1.39 |
-3.48 |
|
NIPIPPPPP |
11.47
|
-4.37 |
-6.46 |
|
MGQPKDPKF |
11.69
|
-3.12 |
-5.21 |
| P38753 |
YSPYPSNLP |
9.09
|
-0.57 |
-2.66 |
|
NLPIQHPTN |
10.37
|
-4.04 |
-6.13 |
|
PSNLPIQHP |
11.41
|
-2.45 |
-4.54 |
| P38237 |
ENFQIPSKP |
11.76
|
-0.96 |
-3.05 |
|
NFQIPSKPE |
11.84
|
-0.94 |
-3.03 |
|
PDLNDPFVP |
12.99
|
-1.08 |
-3.17 |
| P34245 |
YSTPFGPWP |
10.34
|
-0.21 |
-2.30 |
|
AYSTPFGPW |
11.55
|
-0.71 |
-2.80 |
|
FGPWPGPAE |
12.25
|
-1.36 |
-3.45 |
| Q01389 |
RYPQTPSYY |
9.55
|
-2.15 |
-4.24 |
|
KRSKPLPPQ |
10.13
|
-1.43 |
-3.52 |
|
TEPSTPSRP |
11.09
|
-0.65 |
-2.74 |
| Q03306 |
NKSIPRTKP |
8.04
|
-3.18 |
-5.27 |
|
GEEKPFRIP |
8.89
|
-1.97 |
-4.06 |
|
LGTVPSTTP |
9.65
|
-2.82 |
-4.91 |
| P34758 |
QLPLEPLKP |
8.35
|
-4.34 |
-6.43 |
|
QSIKPSSTP |
9.90
|
-1.45 |
-3.54 |
|
LSSSPSPNP |
10.15
|
-0.72 |
-2.81 |
| P53933 |
YNDLPMELP |
7.96
|
-2.52 |
-4.61 |
|
RRPPPPPIP |
10.51
|
-3.50 |
-5.59 |
|
TRRRPPPPP |
10.57
|
-1.57 |
-3.66 |
| P32381 |
LLTEPPMNP |
10.31
|
-1.39 |
-3.48 |
| Q00453 |
YFPHPMPSA |
9.32
|
-1.77 |
-3.86 |
|
SAPIPLPHQ |
9.78
|
-1.75 |
-3.84 |
|
YAPPYFPHP |
10.31
|
-1.35 |
-3.44 |
| P40021 |
NYVISPNLP |
9.86
|
-2.05 |
-4.14 |
|
FLPSTPSQM |
10.55
|
-3.27 |
-5.36 |
|
SESHPPNHP |
10.92
|
-1.50 |
-3.59 |
| P36150 |
PIVVNPSSP |
12.64
|
-2.86 |
-4.95 |
| Q12446 |
FAPLPDPPQ |
9.18
|
-4.70 |
-6.79 |
|
PFPVPQQQF |
9.51
|
-2.76 |
-4.85 |
|
RLPAPPPPP |
10.22
|
-3.34 |
-5.43 |
| Q01560 |
PEPQPYYPP |
12.32
|
-0.51 |
-2.60 |
|
HHQPPEPQP |
12.33
|
-0.27 |
-2.36 |
|
SAPQEPPAP |
12.55
|
-0.41 |
-2.50 |
| P00950 |
RSFDVPPPP |
12.49
|
-1.34 |
-3.43 |
| P53735 |
LVPPPPRTR |
11.35
|
-3.28 |
-5.37 |
|
PKLVPPPPR |
12.05
|
-2.57 |
-4.66 |
|
PAPKLVPPP |
13.18
|
-1.87 |
-3.96 |
| P33334 |
MSGLPPPPP |
9.50
|
-3.78 |
-5.87 |
|
LFFDPSLNP |
9.64
|
-2.10 |
-4.19 |
|
DLALPPPPP |
10.32
|
-3.18 |
-5.27 |
| P40523 |
YMHNSPRNP |
7.23
|
-1.70 |
-3.79 |
|
GGPLASPTH |
10.59
|
-3.77 |
-5.86 |
|
ENITPLPTP |
10.96
|
-0.68 |
-2.77 |
| P40563 |
PSERPKRRA |
8.67
|
-0.79 |
-2.88 |
|
KRRAPPPVP |
10.75
|
-1.92 |
-4.01 |
|
GMVNPGQLP |
10.95
|
-1.16 |
-3.25 |
| Q08989 |
DHPKGPPPP |
12.63
|
-1.24 |
-3.33 |
|
TNGDHPKGP |
13.30
|
-0.79 |
-2.88 |
|
NGDHPKGPP |
13.80
|
-1.60 |
-3.69 |
| P37370 |
VSQMPKPRP |
8.58
|
-2.20 |
-4.29 |
|
LAPLPPPPP |
8.79
|
-3.97 |
-6.06 |
|
RPHMPSVRP |
9.92
|
-3.41 |
-5.50 |
| P39743 |
NATIPEDNP |
10.19
|
-1.83 |
-3.92 |
|
AYSNPLTSP |
11.08
|
-0.80 |
-2.89 |
|
SNPLTSPVA |
11.81
|
-1.44 |
-3.53 |
| Q03900 |
HLPNTPSGA |
11.74
|
-0.14 |
-2.23 |
|
LPNTPSGAP |
14.06
|
0.79 |
-1.30 |
|
GSHLPNTPS |
14.57
|
-1.14 |
-3.23 |
|
